Article
Biophysics
Hisao Honda
Summary: This study focuses on the mechanism of chiral helical looping in the embryonic heart development of mammals and birds. Simulations suggest that a biased contractile force of cell boundaries on the ventral surface of the heart guides convergent extension of collective cells, leading to the formation of a left-handed helical loop. The loop formation process involves two distinct phases of preparation and explicit looping.
BIOPHYSICAL JOURNAL
(2021)
Biographical-Item
Developmental Biology
Chris Wylie, Claudio D. Stern
Summary: Ruth Bellairs, a legendary figure in chick embryology, pioneered new techniques and made important discoveries. Her mentorship had a profound impact on us.
Article
Agriculture, Dairy & Animal Science
Xi Sun, Yumeng Wang, Chaohui Wang, Yibin Wang, Zhouzheng Ren, Xin Yang, Xiaojun Yang, Yanli Liu
Summary: The aim of this study was to reveal the epigenetic mechanism of hepatic tran-scriptional reprogramming changes during the embryonic period of chicken. The results showed gradual increase in lipid contents and decline in H3K27ac and H3K4me2 levels with embryonic age. Differential expression genes (DEGs) were determined through transcriptome analysis. Furthermore, the integration of RNA-seq and CUT&Tag data revealed the involvement of H3K27ac histone modification in transcriptional reprogramming regulation and the recruitment of transcription factors (TFs) to mediate differential enhancer activation.
Article
Biology
Kara E. Peak, Shelby R. Mohr-Allen, Jason P. Gleghorn, Victor D. Varner
Summary: During airway branching morphogenesis, the presence of FGF-10 can promote epithelial buckling and the formation of additional buds. The formation of branches induced by FGF-10 can be regulated by epithelial tension and luminal fluid pressure. Increased tension suppresses the formation of ectopic branches, while the collapse of the airway promotes more expansive buckling and the formation of additional buds.
Review
Physiology
Servet Yalcin, Sezen oezkan, Tahir Shah
Summary: During incubation, temperature and light are two key factors that affect embryo development and post-hatch performance. Optimizing incubation temperature can improve hatchability, while light during incubation can enhance embryo development, reduce stress responses, and improve cognitive functions of chickens.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Cell Biology
Benjamin E. Peterson, Rebecca A. Rolfe, Allen Kunselman, Paula Murphy, Spencer E. Szczesny
Summary: The study revealed that during development, the increase in tendon macroscale modulus is accompanied by an increase in collagen fibril length, highlighting the importance of mechanical stimulation in inducing structural and mechanical changes. The multiscale structure and mechanical changes of tendons are significantly influenced by mechanical stimulation.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Maria Isabella Negretti, Nina Boese, Natalia Petri, Stanislav Kremnyov, Nikoloz Tsikolia
Summary: The development of visceral left-right asymmetry in bilateria relies on initial symmetry breaking and subsequent molecular patterning. The expression of the transcription factor pitx2 on the left side is facilitated by the asymmetric expression of the nodal morphogen in the left lateral plate mesoderm. The mechanisms leading to the asymmetric nodal domain differ depending on the mode of symmetry breaking.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Yanqiang Geng, Xiaoming Sun, Lin Lu, Xi Lin, Xiudong Liao, Liyang Zhang, Runlian Wang, Xugang Luo
Summary: This study aimed to investigate the effects of in ovo manganese injection on embryonic development, antioxidant capacity, and performance of offspring broilers. The results showed that in ovo manganese injection can enhance the antioxidant capacity in the chick embryonic heart, but high temperature can negatively affect the growth performance of the offspring broilers.
Article
Cell Biology
Stefanie H. Korntner, Aniket Jana, Elizabeth Kinnard, Emily Leo, Timothy Beane, Xianmu Li, Rohit Sengupta, Lauren Becker, Catherine K. Kuo
Summary: Using chick embryos as a model, this study identified markers involved in limb tendon formation present in jaw tendons during embryonic development. Results suggest potential therapeutic approaches for CF tendon injuries and disorders by understanding the extracellular matrix development of jaw tendons.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Biophysics
Javier Navarro, Antonion Korcari, Phong Nguyen, Ibrahima Bah, Abdulrahman AlKhalifa, Spencer Fink, Mark Buckley, Catherine K. Kuo
Summary: This paper introduces a marking protocol for mechanical testing of chick embryo tendons, addressing the challenges of small and delicate tendon structures. Results from tendons isolated using the marking protocol show non-linear increases in mechanical properties, highlighting the differences compared to tendons isolated by naked eye.
JOURNAL OF BIOMECHANICS
(2022)
Article
Cardiac & Cardiovascular Systems
Nina Kraus, Fabian Placzek, Brian Metscher
Summary: Researchers have introduced a multimodal imaging workflow combining OCT and micro-CT imaging for modeling early chick heart development. Their goal is to provide new insights into normal cardiac development and congenital heart disease through this approach.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2022)
Article
Agriculture, Dairy & Animal Science
Ezaldeen Abdelghani, Mohamed A. Fathi, Li Zhojian, Dai Pengyuan, Yansen Li, Chunmei Li
Summary: This study aimed to evaluate the effects of in ovo injection of soy isoflavones (ISF) on hatchability, body weight, antioxidant status, and intestinal development of newly hatched broiler chicks. The results showed that the in ovo inclusion of 6 mg of ISF significantly increased hatchability and hatch weight. ISF treatments also improved antioxidant status, intestinal development, and modulated the expression of proinflammatory cytokines, tight junctions, and insulin-like growth factor.
JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Elena Koudouna, Robert D. Young, Andrew J. Quantock, James R. Ralphs
Summary: The cornea is the tough and transparent anterior part of the eye that plays a major role in vision. In embryonic chicken corneas, fibronectin and tenascin-C are present in the primary stroma and have distinctive roles in cell migration and adhesion. Fibronectin acts as an adhesive while tenascin-C is antiadhesive and can displace cells from their adhesion to fibronectin, suggesting their involvement in controlling migration and adhesion.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Dong Dai, Hai-jun Zhang, Kai Qiu, Guang-hai Qi, Jing Wang, Shu-geng Wu
Summary: The early colonization of intestinal microbiota in embryonic stage is crucial for intestinal development, and in ovo feeding of L-arginine has been shown to enhance intestinal development and alter microbial composition in chick embryos. Moreover, prenatal Arg supplementation also regulates glucose and lipid homeostasis, shapes microbial assembly patterns, and enriches potential probiotics in embryonic intestine. These findings suggest that manipulating prenatal host-microbe interactions through nutritional strategies may help establish health-promoting microbiota for the healthy development of neonates.
FRONTIERS IN NUTRITION
(2021)
Article
Agriculture, Dairy & Animal Science
Z. Kankova, A. Drozdova, V Hodova, M. Zeman
Summary: The light regime during incubation can influence the development and reactivity of the immune system in chicks, but this effect is not apparent during later development.
BRITISH POULTRY SCIENCE
(2022)
Article
Engineering, Biomedical
Meagan E. Carnes, George D. Pins
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2020)
Article
Cell & Tissue Engineering
Meagan E. Carnes, Cailin R. Gonyea, Rebecca G. Mooney, Jane W. Njihia, Jeannine M. Coburn, George D. Pins
TISSUE ENGINEERING PART C-METHODS
(2020)
Review
Biotechnology & Applied Microbiology
Meagan E. Carnes, George D. Pins
BIOENGINEERING-BASEL
(2020)
Article
Cell & Tissue Engineering
Megan P. O'Brien, Meagan E. Carnes, Raymond L. Page, Glenn R. Gaudette, George D. Pins
CURRENT STEM CELL REPORTS
(2016)