期刊
DEVELOPMENTAL CELL
卷 19, 期 6, 页码 791-792出版社
CELL PRESS
DOI: 10.1016/j.devcel.2010.11.014
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资金
- Howard Hughes Medical Institute Funding Source: Medline
- NIGMS NIH HHS [R01 GM060124] Funding Source: Medline
Many inhibitor of apoptosis proteins (IAPs) function as E3 ligases to ubiquitinate important cell death proteins, including caspases. Broemer et al. (2010) report recently in Molecular Cell that IAPs can also inhibit caspases by promoting conjugation of the UBL NEDD8.
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