☆ 4.7 Editorial Material

Hematopoietic lineage commitment:: miRNAs add specificity to a widely expressed transcription factor

DEVELOPMENTAL CELL (2008)

期刊

DEVELOPMENTAL CELL

卷 14, 期 6, 页码 815-816

出版社

CELL PRESS

DOI: 10.1016/j.devcel.2008.05.011

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Cell Biology Developmental Biology

资金

Medical Research Council [G9818340B] Funding Source: researchfish

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Reagent

摘要

MicroRNAs are important regulators of normal and malignant hematopoiesis. A paper by Lu et al. in this issue of Developmental Cell demonstrates how one microRNA, miR-150, plays a critical role in commitment of the erythroid-megakaryocyte progenitor by modulating the level of the widely expressed transcription factor MYB (or c-Myb).

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