Article
Cell Biology
Wei Zhang, Wenqun Zhong, Beike Wang, Jiegang Yang, Jingbo Yang, Ziyan Yu, Zhiyuan Qin, Alex Shi, Wei Xu, Cathy Zheng, Lynn M. Schuchter, Giorgos C. Karakousis, Tara C. Mitchell, Ravi Amaravadi, Meenhard Herlyn, Haidong Dong, Phyllis A. Gimotty, George Daaboul, Xiaowei Xu, Wei Guo
Summary: This study reveals the co-localization of ICAM-1 and PD-L1 on exosomes, both of which are upregulated by interferon-y. The adhesion between TEVs and T cells mediated by ICAM-1-LFA-1 is crucial for exosomal PD-L1-mediated immune suppression.
DEVELOPMENTAL CELL
(2022)
Review
Oncology
Yueyuan Wang, Jingyu Peng, Xiao Xie, Zhihao Zhang, Mingxi Li, Ming Yang
Summary: GSDME, an effector of secondary necrosis, has been identified as a tumor suppressor in cancer tissues. It interacts with multiple pathways of cell death, including apoptosis and autophagy, demonstrating potential anti-cancer activity.
Review
Microbiology
Darshika J. Udawatte, Alan L. Rothman
Summary: RIPK1 serves as a key regulator of cell death and inflammation, affecting the outcome of virus infections through activation of different signaling pathways. Viruses manipulate host immune responses by targeting RIPK1, highlighting potential directions for future research.
Article
Fisheries
Charles P. Madenjian
Summary: This study investigated the temporal trends in the biomass density of yearling and older alewife in Lake Michigan, and found that predation was the main driver of the changes in biomass density.
CANADIAN JOURNAL OF FISHERIES AND AQUATIC SCIENCES
(2022)
Article
Ecology
H. Andres Araujo, William D. P. Duguid, Ruth Withler, Janine Supernault, Angela D. Schulze, Jessica L. Mckenzie, Kevin Pellett, Terry D. Beacham, Kim Jonsen, Anna Gummer
Summary: Between 2013 and 2019, 63 presumed hybrid Chinook-Coho salmon were identified in the Georgia Strait, primarily resulting from the hybridization of Coho salmon females and Chinook salmon males. These hybrids were found to have abnormal scale arrangements and an intermediate pyloric caeca count. The prevalence of hybrids in the watershed is a naturally occurring event, potentially exacerbated by prolonged low water levels and differential abundance of parental species. This research is the first to document ongoing natural hybridization and its links to habitat and climatic changes, highlighting the importance of hybrid identification as an ecosystem monitoring tool.
ECOLOGY AND EVOLUTION
(2021)
Article
Food Science & Technology
Lijin Duan, Shasha Zhang, Yingxia Yang, Qian Wang, Qingkuo Lan, Yong Wang, Wentao Xu, Wujun Jin, Liang Li, Rui Chen
Summary: This study introduces a novel GMO testing method, "SSH-seq", based on suppressive subtractive hybridization and next-generation sequencing, which can be used to detect unknown GMOs and has shown promising results in experiments. Although the method may be influenced by multiple factors, further optimizations could make SSH-seq a powerful tool in the field of GMO testing.
Article
Fisheries
Huaxing Su, Yitong Zhang, Zhongwei He, Yucong Yang, Yuqin Ren, Wei Cao, Yufeng Liu, Jiangong Ren, Yufen Wang, Guixing Wang, Jilun Hou
Summary: It has been found that the flatfish farming industry is threatened by Chinook salmon bafinivirus (CSBV) induced hemorrhagic disease. Therefore, the development of a rapid and efficient diagnostic method is crucial for disease control in aquaculture. This research evaluated the loop-mediated isothermal amplification (LAMP) technique for the detection of CSBV, and it showed high specificity and sensitivity, with a positive detection rate of 100% in naturally infected flatfish samples.
AQUACULTURE INTERNATIONAL
(2023)
Article
Plant Sciences
Ting Yang, Yi Xin, Tongyao Liu, Zhengfeng Li, Xingzhong Liu, Yunpeng Wu, Mingfeng Wang, Meichun Xiang
Summary: This study identified a rhizosphere bacterium, strain NC1, which showed strong inhibition against root-knot nematodes. Gas chromatography-mass spectrometry analysis revealed that the strain produced volatile compounds, DMDS and benzaldehyde, that exhibited nematicidal activity. A greenhouse trial demonstrated that the strain effectively controlled root-knot nematodes.
Article
Agriculture, Dairy & Animal Science
Pedro Luis Castro, Fran Barac, Tom Johnny Hansen, Per Gunnar Fjelldal, Ivar Hordvik, Havard Bjorgen, Erling Olaf Koppang
Summary: In this study, the distribution of IgT and pIgR mRNA(+) cells in the gut of Atlantic salmon was investigated using RNAscope in situ hybridization. The results showed that the distribution of IgT mRNA(+) cells is region-specific and varies with fish age, while intraperitoneal vaccination had no significant impact on the number of IgT(+) transcripts.
Article
Multidisciplinary Sciences
Kojiro Tsujihana, Kosuke Tanegashima, Yasuko Santo, Hiroyuki Yamada, Sota Akazawa, Ryuta Nakao, Keiko Tominaga, Risa Saito, Yasumasa Nishito, Ryu-Ichiro Hata, Tomonori Nakamura, Iori Murai, Yuka Kono, Maho Sugawa, Miki Tanioka, Gyohei Egawa, Masao Doi, Tadashi Isa, Kenji Kabashima, Takahiko Hara, Hitoshi Okamura
Summary: The epidermis, the outermost layer of skin, acts as a primary barrier against external pathogens. The early immune response in the epidermis is still not well understood, but research has shown that keratinocytes exhibit circadian fluctuations and can activate innate immunity. In nocturnal mice, the expression of CXCL14, a chemokine, is associated with clearance of the skin pathogen Staphylococcus aureus, with high expression during the subjective daytime and low expression at night. However, in diurnal primates like marmosets, CXCL14 expression is reversed. These findings suggest that the circadian production of CXCL14 plays a role in suppressing skin bacterial proliferation by activating the innate immune system.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Fisheries
Liming Xu, Jingzhuang Zhao, Miao Liu, Guangming Ren, Shi Cheng Han, Yizhi Shao, Yongsheng Cao, Hongbai Liu, Tongyan Lu
Summary: IHNV enhances the multiplication of IPNV during co-infection, with the enhancement becoming stronger with increasing infection time interval, regardless of the infection order.
Article
Immunology
Mario Fernandez-Ruiz, Beatriz Olea, Estela Gimenez, Rocio Laguna-Goya, Hernando Trujillo, Fernando Caravaca-Fontan, Eduardo Gutierrez, Francisco Lopez-Medrano, Maria Jose Remigia, Patricia Almendro-Vazquez, Natalia Polanco, Esther Gonzalez, Tamara Ruiz-Merlo, Patricia Parra, Rafael San Juan, Amado Andres, David Navarro, Jose Maria Aguado
Summary: Although still exploratory and limited by small sample size, the present study suggests that a substantial proportion of kidney transplant recipients exhibited detectable SARS-CoV-2-specific cell-mediated immunity after 6 months from COVID-19 diagnosis.
Article
Biochemistry & Molecular Biology
Marta Robledo, Beatriz Alvarez, Ana Cuevas, Sheila Gonzalez, David Ruano-Gallego, Luis Angel Fernandez, Fernando de la Cruz
Summary: This study presents a synthetic bacterial adhesion system that enhances the delivery of genetic cargo to targeted recipients, overcoming the challenges of genetic interventions on microbiomes. The system allows for efficient conjugation and transfer of plasmids, particularly in liquid media, and enables selective gene delivery to desired hosts.
NUCLEIC ACIDS RESEARCH
(2022)
Article
Multidisciplinary Sciences
G. Rizzuto, J. F. Brooks, S. T. Tuomivaara, T. I. McIntyre, S. Ma, D. Rideaux, J. Zikherman, S. J. Fisher, A. Erlebacher
Summary: The recognition and tolerance of the placenta by the maternal immune system is crucial for a healthy pregnancy. This study provides evidence that glycan-mediated B cell suppression plays a key role in establishing fetomaternal tolerance in mice. The release of trophoblast-derived sialoglycoproteins into the maternal circulation during pregnancy suggests potential implications for immune-mediated pregnancy complications and tumor immune evasion.
Article
Biochemistry & Molecular Biology
Julian Gruetzner, Bernhard Remes, Katrin M. H. Eisenhardt, Daniel Scheller, Jonas Kretz, Ramakanth Madhugiri, Matthew McIntosh, Gabriele Klug
Summary: Tightly controlled cell division is crucial for most organisms' survival. The small non-coding sRNA StsR is shown to play a significant role in regulating cell division and growth in the alpha-proteobacterium Rhodobacter sphaeroides. StsR interacts with UpsM and dcw mRNA to affect the level of dcw mRNA and ultimately limit growth.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Environmental Sciences
Zack S. Oyafuso, Anne E. Baxter, Jason E. Hall, Sean M. Naman, Correigh M. Greene, Linda D. Rhodes
JOURNAL OF WATER AND HEALTH
(2015)
Article
Fisheries
Linda D. Rhodes, Ronald B. Johnson, Mark S. Myers
Article
Ecology
Sean M. Naman, Correigh M. Greene, Casimir A. Rice, Joshua Chamberlin, Letitia Conway-Cranos, Jeffery R. Cordell, Jason E. Hall, Linda D. Rhodes
ECOLOGY AND EVOLUTION
(2016)
Article
Fisheries
L. L. Gustafson, L. H. Creekmore, K. R. Snekvik, J. A. Ferguson, J. V. Warg, M. Blair, T. R. Meyers, B. Stewart, K. I. Warheit, J. Kerwin, A. E. Goodwin, L. D. Rhodes, J. E. Whaley, M. K. Purcell, C. Bentz, D. Shasa, J. Bader, J. R. Winton
JOURNAL OF FISH DISEASES
(2018)
Article
Fisheries
Paul Hershberger, Linda Rhodes, Gael Kurath, James Winton
Article
Ecology
Ola Brynildsrud, Edward J. Feil, Jon Bohlin, Santiago Castillo-Ramirez, Duncan Colquhoun, Una McCarthy, Iveta M. Matejusova, Linda D. Rhodes, Gregory D. Wiens, David W. Verner-Jeffreys
Article
Ecology
Linda D. Rhodes, Casimir A. Rice, Correigh M. Greene, David J. Teel, Shelly L. Nance, Paul Moran, Colleen A. Durkin, Surafel B. Gezhegne
MARINE ECOLOGY PROGRESS SERIES
(2011)
Article
Multidisciplinary Sciences
Nathaniel L. Scholz, Mark S. Myers, Sarah G. McCarthy, Jana S. Labenia, Jenifer K. McIntyre, Gina M. Ylitalo, Linda D. Rhodes, Cathy A. Laetz, Carla M. Stehr, Barbara L. French, Bill McMillan, Dean Wilson, Laura Reed, Katherine D. Lynch, Steve Damm, Jay W. Davis, Tracy K. Collier
Article
Multidisciplinary Sciences
Stephen A. Raverty, Linda D. Rhodes, Erin Zabek, Azad Eshghi, Caroline E. Cameron, M. Bradley Hanson, J. Pete Schroeder
SCIENTIFIC REPORTS
(2017)
Review
Fisheries
Aaron D. Jackson, Mary L. Moser, Sam T. Onjukka, Scott LaPatra, Kenneth M. Lujan, Corie Samson, Melissa G. White, Marilyn Blair, Linda Rhodes, Ralph Lampman, Alexa N. Maine, Jeffrey C. Jolley
REVIEWS IN FISH BIOLOGY AND FISHERIES
(2019)
Article
Environmental Sciences
Jessica L. Huggins, Michael M. Garner, Stephen A. Raverty, Dyanna M. Lambourn, Stephanie A. Norman, Linda D. Rhodes, Joseph K. Gaydos, Jennifer K. Olson, Martin Haulena, M. Bradley Hanson
FRONTIERS IN MARINE SCIENCE
(2020)
Article
Environmental Sciences
Sarah A. Morley, Linda D. Rhodes, Anne E. Baxter, Giles W. Goetz, Abigail H. Wells, Katherine D. Lynch
Summary: This study introduces a new urban floodplain restoration technique - engineered hyporheic zone - which shows potential in improving temperature moderation, habitat diversity, and biological health of restored urban streams. The research quantifies the positive responses of hyporheic biological communities to restoration efforts, indicating enhanced hydrologic and chemical functioning of the engineered hyporheic zone.
Article
Environmental Sciences
Stephanie A. Norman, Jessica L. Huggins, Dyanna M. Lambourn, Linda D. Rhodes, Michael M. Garner, Jennie L. Bolton, Joseph K. Gaydos, Alyssa Scott, Stephen Raverty, John Calambokidis
Summary: Mucorales infections are increasing in frequency and pose a concern as a One Health pathogen. Risk factors for these infections in harbor porpoises are still unknown, but a risk factor analysis found elevated liver iron, decreased blubber thickness, and the decreased ratio of PCB congeners/PBDE congeners to be strongly associated with the infection. The study suggests that harbor porpoises may face a high risk of Mucorales infections based on the prevalence and severity of observed lesions.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Biodiversity Conservation
Linda D. Rhodes, Candice K. Emmons, GabrielS Wisswaesser, Abigail H. Wells, M. Bradley Hanson
Summary: Opportunities to assess the health of odontocetes are limited, but this study demonstrates the value of analyzing non-invasive samples such as expelled mucus and exhaled breath. The research focused on the bacterial microbiomes of southern resident killer whales and identified differences between mucus, breath, and seawater samples. The study also emphasized the importance of genotyping mucus samples to better understand an individual animal's health.
CONSERVATION PHYSIOLOGY
(2022)
Article
Genetics & Heredity
Ola Brynildsrud, Snorre Gulla, Edward J. Feil, Simen Foyn Norstebo, Linda D. Rhodes
MICROBIAL GENOMICS
(2016)
Article
Fisheries
Ratiporn Thongsoi, Siriluk Maskaew, Panumas Puechpon, Benjaporn Noppradit, Napassawan Inaek, Prapaporn Utarabhand, Phanthipha Runsaeng
Summary: In this study, a PPAE gene called FmPPAE1 was cloned and analyzed in banana shrimp. FmPPAE1 plays a vital role in regulating the proPO system, exhibits antibacterial properties, and contributes to the suppression of bacterial proliferation.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Jishuang Tan, Paizelaiti Sahaer, Huan Li, Wei Han, Hongyan Sun
Summary: Circular RNAs (circRNA) are involved in gene expression and affect cellular processes such as transcription, splicing, and translation by interacting with microRNA and RNA binding proteins. A study identified circDNAJB6 as a circular RNA abundant in chicken macrophages after bacterial infection, and found that circDNAJB6 exacerbates cellular injury and interacts with multiple miRNAs and target genes, potentially impacting autophagy and MAPK signaling pathways.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Rodrigo Guabiraba, Damaris Ribeiro Rodrigues, Paul T. Manna, Melanie Chollot, Vincent Saint-Martin, Sascha Trapp, Marisa Oliveira, Clare E. Bryant, Brian J. Ferguson
Summary: The innate immune response relies on the ability of host cells to detect and respond to microbial nucleic acids. Toll-like receptors (TLRs) play a crucial role in this process by distinguishing self from non-self. This study focused on TLR21, an avian TLR that recognizes bacterial DNA motifs. The findings suggest that avian TLR21 shares similar activation mechanisms to mammalian TLR9, highlighting the conservation of nucleic acid sensing mechanisms across species.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Safieh Zeinali, Kate Sutton, Lonneke Vervelde
Summary: Chickens have a unique immune structure characterized by the absence of draining lymph nodes and the presence of well-developed mucosa-associated lymphoid tissue. The structure and development of chicken lymphoid tissues in the intestine, particularly Peyer's patches, have been poorly studied. However, the use of CSF1R-eGFP reporter transgenic chickens has allowed for the visualization and investigation of the development and distribution of these tissues. This research provides insights that could benefit mucosal vaccination strategies and the development of targeted vaccine delivery systems.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Retraction
Fisheries
G. -g. Li, Z. -z. Guo, X. -f. Ma, N. Cao, S. -n. Geng, Y. -q. Zheng, M. -j. Meng, H. -h. Lin, G. Han, G. -j. Du
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Jinyue Yang, Peng Zhou, Wanrong Wu, Qingxiang Zhang, Dong Chen, Rui Luo
Summary: This study cloned and characterized the full-length sequence of duck MRE11 (duMRE11) for the first time, and found that this protein plays an important role in the innate immune response of ducks.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Mengjiao Guo, Jiaqi Zhang, Mingtao Li, Xiaorong Zhang, Yantao Wu
Summary: rNLRC3 negatively regulates the NF -KB signaling pathway induced by P. multocida in rabbits by inhibiting the activation of NF -KB, reducing the expression of inflammatory cytokines, and interacting with rTRAF4 and rTRAF6. The NACHT-LRR domain is the functional domain of rNLRC3. These findings provide insights into the important role of rNLRC3 in combating P. multocida infection.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Yinan Li, Xingye Lian, Wenwen Yang, Jinyuan Leng, Jiejie Sun, Yu Liu, Siqi Fan, Lingling Wang, Linsheng Song
Summary: The DM9-containing protein CgDM9CP-7 plays an important role in the innate immune response of molluscs. It is constitutively expressed in various tissues and is up-regulated in haemocytes after stimulation by Vibrio splendidus and lipopolysaccharide (LPS). CgDM9CP-7 binds to various pathogens and exhibits antimicrobial activity, while also regulating the expression of CgMyD88 and CgIL-17.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)
Article
Fisheries
Xiuwen Bao, Haoran Song, Liying He, Yong Li, Shuqi Niu, Jinlin Guo
Summary: This study focuses on the interaction between Hepialus xiaojinensis larvae and Ophiocordyceps sinensis during the infection process. The results show that the infected third instar larvae enhance antioxidant defense ability, while the infected fourth instar larvae reduce this ability and allocate more energy to growth and development.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2024)