4.7 Article

Copper-Catalyzed N-Cyanation of Sulfoximines by AIBN

期刊

JOURNAL OF ORGANIC CHEMISTRY
卷 80, 期 5, 页码 2822-2826

出版社

AMER CHEMICAL SOC
DOI: 10.1021/jo502607c

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资金

  1. National Natural Science Foundation of China [21272028, 21202013]
  2. Innovation & Entrepreneurship Talents Introduction Plan of Jiangsu Province
  3. Jiangsu Key Laboratory of Advanced Catalytic Materials Technology [BM2012110]
  4. Jiangsu Province Key Laboratory of Fine Petrochemical Engineering
  5. Priority Academic Program Development of Jiangsu Higher Education Institutions
  6. Open Research Fund of Top Key Discipline of Chemistry in Zhejiang Provincial Colleges

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The direct copper-catalyzed N-cyanation of sulfoximines was achieved by using AIBN as a safe cyanide source. It represents a simple and environmentally benign procedure for the construction of the N-CN bond. Furthermore, some sec-amines can also be tolerated well under this procedure.

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