Skeletal Diversity from Carbohydrates: Use of Mannose for the Diversity-Oriented Synthesis of Polyhydroxylated Compounds

The application of d-mannose as a multipurpose building block from the chiral pool enabled the diversity-oriented synthesis of an array of cyclic and bicyclic scaffolds with polyhydroxylated appendages with the aim to expand the skeletal diversity in the panorama of glycopeptidomimetic compounds.