期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 80, 期 3, 页码 2024-2031出版社
AMER CHEMICAL SOC
DOI: 10.1021/jo5028886
关键词
-
资金
- CSIR, New Delhi, India (Indus MAGIC project) [CSC-0123]
- DST [SR/S1/OC-67/2010]
- CSIR, New Delhi, India
A highly efficient one-pot [4 + 1]-annulation process for the asymmetric synthesis of densely functionalized pyrrolidine derivatives is described. The in situ generated syn-Mannich adduct obtained via proline catalysis acts as a four-atom component, and Coreys sulfur ylide or ethyl bromoacetate acts as a one-atom carbon source to construct pyrrolidine units in a highly enantio- and diastereoselective manner.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据