Review
Psychiatry
Aleksander Kwasny, Adam Wlodarczyk, Alicja Dywel, Joanna Szarmach, Olivia Strandberg, Wieslaw Jerzy Cubala
Summary: The ultimate goal in MDD treatment is recovery, but some patients still experience residual symptoms such as insomnia, affecting their daily functioning. Residual insomnia, especially mid-nocturnal insomnia, is common in MDD patients and is associated with earlier relapse and poor prognosis. Several non-pharmacological treatments such as CBT-I, MBCT, BA, and pharmacological treatments like gabapentin and clonazepam have proven to be effective in mitigating residual insomnia. CBT-D has limited effectiveness in improving insomnia complaints. More research is needed to explore treatment options and understand different subtypes of insomnia in MDD.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Clinical Neurology
Myriam Tanguay-Sela, Colleen Rollins, Tamara Perez, Vivian Qiang, Grace Golden, Jingla-Fri Tunteng, Kelly Perlman, Jade Simard, David Benrimoh, Howard C. Margolese
Summary: This study aims to identify known predictors of individual response to psychological therapy. By synthesizing various predictors, it can help in selecting therapy and developing machine learning models to predict patient responses to different treatment options.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Psychiatry
Yufei Wu, Danni Yan, Jianli Yang
Summary: This study aimed to explore further the efficacy of yoga for patients with MDD. Analysis of 34 RCT studies showed that yoga had a moderate effect on improving depressive symptoms and severity, but had a negligible effect on anxiety levels. No adverse events occurred in the yoga group during treatment.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Multidisciplinary
Irene Ramos-Grille, Nuria Aragay, Sergi Valero, Gemma Garrido, Marti Santacana, Roser Guillamat, Vicenc Valles, Montserrat Goma-I-Freixanet
Summary: Neuroticism-Anxiety is closely related to a diagnosis of depression, while the activity trait is associated with a reduced likelihood of being depressed. These findings help to clarify the links between personality and depression.
CURRENT PSYCHOLOGY
(2022)
Article
Clinical Neurology
Alasdair Vance, Jo Winther
Summary: The study revealed that MDD is associated with more severe SWM impairment compared to DD, and there is no additive effect of MDD and DD on SWM deficits. Furthermore, these findings are consistent across different age groups.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Clinical Neurology
Priscila R. Toledo, Francisco Lotufo-Neto, Helen Verdeli, Alessandra C. Goulart, Andrea Horvath Marques, Ana Cristina de Oliveira Solis, Yuan-Pang Wang
Summary: The study compared the effects of different interventions on weight loss, binge eating behaviors, and depressive symptoms in patients with overweight/obesity and depression. The results showed that interpersonal psychotherapy (IPT) had some benefits for these patients compared to other interventions.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Clinical Neurology
Kody G. Kennedy, Megan Mio, Benjamin I. Goldstein, Paolo Brambilla, Giuseppe Delvecchio
Summary: This review and meta-analysis found that individuals with severe mental illness, especially schizophrenia, have wider retinal venules compared to controls, indicating a potential connection between cerebrovascular health and mental illness.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Psychiatry
Damien Etchecopar-Etchart, Theo Korchia, Anderson Loundou, Pierre-Michel Llorca, Pascal Auquier, Christophe Lancon, Laurent Boyer, Guillaume Fond
Summary: This study found a high prevalence of comorbid major depressive disorder in schizophrenia patients, with factors like publication year, study size, assessment tools, comorbid conditions, demographics, hospitalizations, and antidepressant use influencing the prevalence rate. Further research is needed to explore other potential factors contributing to the high prevalence of SZ-MDD.
SCHIZOPHRENIA BULLETIN
(2021)
Review
Psychiatry
Shurui Chen, Hong Wang, Jihui Yue, Nianhong Guan, Xianglan Wang
Summary: This study conducted a systematic review and meta-analysis on the improvement effects of clinical treatments on low heart rate variability (HRV) in patients with major depressive disorder (MDD). The results showed that psychotherapy was effective in improving low HRV in MDD patients, while the effects of pharmacotherapy and physical therapy remained unclear.
COMPREHENSIVE PSYCHIATRY
(2022)
Review
Clinical Neurology
Marie Crowe, Maree Inder, Jenni Manuel, Dave Carlyle
Summary: This review aimed to identify the characteristics of effective psychotherapy delivered by videoconference for adults in primary care with a primary diagnosis of depression. The findings suggest that teletherapy has similar outcomes to in-person therapy for people with depression, but no evidence was found regarding the superiority of one therapy model over others.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Pan Chen, Yuan Feng, Xiao-Hong Li, Jia-Xin Li, Yue-Ying Wang, Wan-Ying Zheng, Zhaohui Su, Teris Cheung, Gabor S. Ungvari, Chee H. Ng, Sha Sha, Yu-Tao Xiang
Summary: This study explored and mapped the research outputs of major depressive disorder (MDD)-related systematic reviews and meta-analyses (SR/MA) using a bibliometric approach. The results showed a rapid increase in the number of SR/MA in recent years, highlighting the importance of this research field. Psychiatric comorbidities, clinical interventions, and treatment of MDD were identified as hot topics, while biological mechanisms in MDD are likely to be an emerging research priority.
FRONTIERS IN PSYCHIATRY
(2023)
Review
Behavioral Sciences
Julie Kristine Knudsen, Caspar Bundgaard-Nielsen, Simon Hjerrild, Rene Ernst Nielsen, Peter Leutscher, Suzette Sorensen
Summary: Gut microbiota in patients with MDD differs significantly from healthy controls, with variations in alpha and beta diversity, as well as specific changes in the relative abundance of certain bacteria. The heterogeneity in findings may be attributed to differences in study design and methodology.
BRAIN AND BEHAVIOR
(2021)
Review
Ergonomics
Sohrab Amiri
Summary: This study found a clear association between unemployment and depressive symptoms and major depressive disorder, with higher prevalence among the unemployed, indicating negative impacts on their mental health.
INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
(2022)
Review
Psychiatry
Aline J. Waclawovsky, Edineia de Brito, Lee Smith, Davy Vancampfort, Antonio M. da Silva, Felipe B. Schuch
Summary: Individuals diagnosed with depression show impaired endothelial dysfunction compared to controls, with HDL cholesterol levels and differences in FMD assessment modalities moderating the difference. The study suggests that clinical depression may lead to greater dysfunction in endothelial function.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Article
Clinical Neurology
Stephan Heinzel, Melanie Schwefel, Alba Sanchez, Darlene Heinen, Lydia Fehm, Romy Henze, Christina Teran, Gunnar Kallies, Michael A. Rapp, Thomas Fydrich, Andreas Strohle, Andreas Heissel
Summary: The study found that high-intensity physical exercise did not universally enhance the outcome of CBT, but higher levels of physical fitness improvement seem to aid in symptom change during CBT. Therefore, future research and clinical practice might consider more individually tailored exercise programs.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Surgery
Thea Kreutzburg, Frederik Peters, Jenny Kuchenbecker, Ursula Marschall, Regent Lee, Levente Kriston, E. Sebastian Debus, Christian-Alexander Behrendt
Summary: The GermanVasc score was developed to predict worse five year amputation free survival for patients with peripheral arterial occlusive disease (PAOD), showing good predictive accuracy stratified for intermittent claudication (IC) and chronic limb threatening ischaemia (CLTI).
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2021)
Review
Psychiatry
Moritz Koehnen, Mareike Dreier, Tharanya Seeralan, Levente Kriston, Martin Haerter, Harald Baumeister, Sarah Liebherz
Summary: This study aims to structure evidence on TBIs by considering different application areas and treatment characteristics in order to provide a comprehensive evidence base and identify research gaps in TBIs for diagnosed depression. The research has given little attention to studying TBIs for aftercare and for bridging waiting periods, highlighting the need for high quality studies in these areas. Additionally, future studies should use specific guidelines to systematically assess and report negative events associated with TBIs.
JMIR MENTAL HEALTH
(2021)
Article
Behavioral Sciences
Rebecca Philipp, Lisa Lebherz, Goetz Thomalla, Martin Haerter, Hannes Appelbohm, Marc Frese, Levente Kriston
Summary: This study examined the psychometric properties of patient-reported outcome measures assessing global health, anxiety, depression, and functioning in German stroke patients. The PROMIS-10 was found to be valid and reliable for measuring HRQoL, while the PHQ-4 was confirmed as a screening tool for mental disorders. Further research is needed on items assessing self-reported functioning in stroke patients with minimal functional deficits.
BRAIN AND BEHAVIOR
(2021)
Article
Oncology
Sigrun Vehling, Anja Mehnert-Theuerkauf, Rebecca Philipp, Martin Harter, Klaus Kraywinkel, Ronny Kuhnert, Uwe Koch
Summary: The study showed that patients with cancer have significantly higher prevalence rates of mental disorders, especially mood disorders and mental disorders due to general medical conditions. Lower occurrence of anxiety disorders in cancer patients was unexpected and may be worth exploring in future research.
Article
Biochemistry & Molecular Biology
Martino Belvederi Murri, Luigi Grassi, Rosangela Caruso, Maria Giulia Nanni, Luigi Zerbinati, Sylke Andreas, Berta Ausin, Alessandra Canuto, Martin Haerter, Manuel Munoz Lopez, Kerstin Weber, Hans-Ulrich Wittchen, Jana Volkert, George S. Alexopoulos
Summary: Late-life depression presents with diverse and heterogeneous clinical features, which were identified in this study as eight symptom complexes through network psychopathology. The study found reciprocal interactions between different symptom complexes, providing potential targets for personalized treatment and biomarker research in late-life depression.
MOLECULAR PSYCHIATRY
(2022)
Article
Health Care Sciences & Services
Eva Christalle, Stefan Zeh, Pola Hahlweg, Levente Kriston, Martin Haerter, Jordis Zill, Isabelle Scholl
Summary: This study aimed to develop and select items for the Experienced Patient-Centeredness (EPAT) Questionnaire to assess patient-centered care from the perspective of adult patients with chronic diseases in Germany. The study used a mixed-method design and generated 125 items assessing 16 dimensions of patient-centered care. The EPAT questionnaire holds promise for evaluating patient-centered care in routine clinical practice and for research and quality improvement purposes.
HEALTH EXPECTATIONS
(2022)
Article
Psychiatry
Hauke Felix Wiegand, Anna-Lena Broecker, Mandy Fehr, Niklas Lohmann, Birgit Maicher, Nikolaus Roethke, Mike Rueb, Paula Wessels, Moritz de Greck, Andrea Pfennig, Stefan Unterecker, Oliver Tuescher, Henrik Walter, Peter Falkai, Klaus Lieb, Lars Peer Hoelzel, Kristina Adorjan
Summary: Psychiatric inpatient treatment in Germany was significantly impacted during the COVID-19 pandemic, with reductions in both inpatient and day hospital treatment observed in many departments. Problems such as lack of integration of patients into their living environment and disease exacerbations were reported due to reduced capacities and insufficient outpatient treatment options.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Health Care Sciences & Services
Leonie Gerke, Soenke Ladwig, Franz Pauls, Manuel Trachsel, Martin Haerter, Yvonne Nestoriuc
Summary: This study describes a randomized controlled web-based trial to investigate the efficacy of a one-session optimized informed consent consultation. By providing information on the setting, efficacy, mechanisms, and negative effects of psychotherapy, the consultation can meet ethical and legal obligations and strengthen contributing factors to psychotherapy outcome.
JMIR RESEARCH PROTOCOLS
(2022)
Article
Multidisciplinary Sciences
Levente Kriston, Lea Schumacher, Pola Hahlweg, Martin Haerter, Isabelle Scholl
Summary: The study found that using the skills network approach allows for the prediction of observer-rated SDM competence from physicians' self-reported SDM skills. By constructing an SDM skills network for each physician and using network parameters, observer-rated SDM competence could be accurately predicted. It is important to note that patient assessments and input are also crucial for predicting physicians' SDM competence.
Article
Health Care Sciences & Services
Linda Baumbach, Marc Frese, Martin Haerter, Hans-Helmut Koenig, Andre Hajek
Summary: This study examined the association between patient satisfaction with physician- and nurse-related care and quality of life and self-rated health among inpatients in a German hospital. The results suggested that higher satisfaction with care was associated with better quality of life and self-rated health.
Article
Psychology, Clinical
Leonie Gerke, Franz Pauls, Soenke Ladwig, Sarah Liebherz, Klaus Michael Reininger, Levente Kriston, Manuel Trachsel, Martin Haerter, Yvonne Nestoriuc
Summary: Optimizing the informed consent consultation can effectively enhance treatment expectations and decision-making in psychotherapy, leading to improved treatment consent capacity and satisfaction. This research highlights the importance of informed consent in psychotherapy.
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
(2023)
Letter
Medicine, General & Internal
Levente Kriston, Sarah Liebherz, Moritz Koehnen
Article
Psychiatry
Hauke F. Wiegand, Birgit Maicher, Mike Rueb, Paula Wessels, Bianca Besteher, Sabine Hellwig, Andrea Pfennig, Henrik Rohner, Stefan Unterecker, Lars P. Hoelzel, Alexandra Philipsen, Katharina Domschke, Peter Falkai, Klaus Lieb, Kristina Adorjan
Summary: The study found that vaccination rates in hospitalized patients with mental illness were lower compared to the general population. Risk factors for nonvaccination included an ICD-10 group F1, F2, or F4 main diagnosis, younger age, and coercive accommodation. By targeting at-risk groups with low-threshold vaccination programs in all health institutions they get in contact with, vaccination rates comparable to those in the general population can be achieved.
EUROPEAN PSYCHIATRY
(2022)