Article
Medicine, General & Internal
Andreea Igna, Cornel Igna, Mariana Ioana Miron, Larisa Schuszler, Roxana Dascalu, Mihaela Moldovan, Adrian Aristide Voicu, Carmen Darinca Todea, Marius Boariu, Maria-Alexandra Martu, Stefan-Ioan Stratul
Summary: This study aimed to evaluate the pulpal response of primary teeth using pulse-oximetry in a canine model after direct pulp capping. The results showed correlations between pulse-oximetry, laser Doppler flowmetry, computer tomographic densitometry, and histological analysis. Different pulp capping materials resulted in varying degrees of pulpal inflammation, which were not correlated with the obtained pulse-oximetry values.
Article
Medicine, General & Internal
Andreea Igna, Darian Rusu, Emilia Ogodescu, Stefania Dinu, Marius Boariu, Adrian Voicu, Stefan-Ioan Stratul
Summary: The study aimed to investigate the age-related variation of blood oxygen saturation from the dental pulp during different stages of tooth development in children. The results showed that blood oxygen saturation tended to decrease with age progression, and there were significant differences between different tooth types and clinical conditions.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Heeresh Shetty, Shishir Shetty, Adesh Kakade, Aditya Shetty, Mohmed Isaqali Karobari, Ajinkya M. Pawar, Anand Marya, Artak Heboyan, Adith Venugopal, The Hanh Nguyen, Dinesh Rokaya
Summary: This study compared the accuracy of two artificial intelligence-based medical imaging programs, OsiriX MD and 3D Slicer, in estimating the volume of pulp space following regenerative endodontic procedures (REPs). The results showed a significant decrease in pulp space volume measured by both programs, with no significant difference in accuracy between them. 3D Slicer, an open-source software program, was found to be as accurate as the commercially available OsiriX MD in volumetric assessment of post-REP pulp space.
SCIENTIFIC REPORTS
(2021)
Article
Multidisciplinary Sciences
Amrita Banerjee, Neha Bhattacharyya, Ria Ghosh, Soumendra Singh, Aniruddha Adhikari, Susmita Mondal, Lopamudra Roy, Annie Bajaj, Nilanjana Ghosh, Aman Bhushan, Mahasweta Goswami, Ahmed S. A. Ahmed, Ziad Moussa, Pulak Mondal, Subhadipta Mukhopadhyay, Debasis Bhattacharyya, Arpita Chattopadhyay, Saleh A. Ahmed, Asim Kumar Mallick, Samir Kumar Pal
Summary: The study evaluated the accuracy of a newly developed spectroscopy-based non-invasive device called SAMIRA for measuring hemoglobin, bilirubin, and oxygen saturation in newborns as an alternative to invasive blood sampling. Transcutaneous values obtained by SAMIRA were compared to biochemical blood tests, and the device was trained using Artificial Neural Network Analysis. The results showed high correlation coefficients and acceptable measurement limits for all three parameters.
SCIENTIFIC REPORTS
(2023)
Article
Pediatrics
Anup C. Katheria, Ana Morales, Sanjay Shashank, Wade D. Rich, Neil N. Finer
Summary: Current guidelines recommend using a cardiac monitor during neonatal resuscitation. Infants assigned to a novel electrocardiogram algorithm had a faster heart rate compared to the conventional algorithm. Although the resuscitation outcomes did not differ, the availability of an earlier heart rate may be beneficial for neonatal providers during high-risk resuscitations.
JOURNAL OF PEDIATRICS
(2022)
Article
Chemistry, Multidisciplinary
Konstantina Kritikou, Marina Imre, Mihaela Tanase, Arina Vinereanu, Alexandra Ripszky Totan, Tudor-Claudiu Spinu, Daniela Miricescu, Iulia-Ioana Stanescu-Spinu, Marilena Bordea, Maria Greabu
Summary: Inflammation in primary teeth often leads to delayed dental treatment due to lower pain sensitivity compared to permanent teeth. This pilot study examined biomarker levels in primary teeth, finding significantly increased levels of various markers in acute and chronically inflamed pulp tissues. Osteocalcin showed particularly higher concentrations in chronically inflamed pulp.
APPLIED SCIENCES-BASEL
(2022)
Review
Dentistry, Oral Surgery & Medicine
Manal Matoug-Elwerfelli, Ahmed S. ElSheshtawy, Monty Duggal, Huei J. Tong, Hani Nazzal
Summary: This systematic review evaluated the success of vital pulp treatment (VPT) in managing traumatic dental injuries involving the pulp. Limited evidence from well-conducted clinical studies supported the overall high success of VPT in managing pulpally involved traumatised permanent teeth.
INTERNATIONAL ENDODONTIC JOURNAL
(2022)
Review
Chemistry, Multidisciplinary
Alicia Almudever-Garcia, Leopoldo Forner, Jose Luis Sanz, Carmen Llena, Francisco Javier Rodriguez-Lozano, Julia Guerrero-Girones, Maria Melo
Summary: This systematic review highlights the potential application of pulse oximetry in diagnosing pulp vitality. While showing good sensitivity and specificity, its clinical use in dentistry is hindered by limitations such as the lack of a specific pulse oximeter for dental practice and insufficient evidence on the impact of different systemic and oral pathologies on pulp oxygen saturation levels.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemical Research Methods
Akshaya V. Annapragada, Joseph L. Greenstein, Sanjukta N. Bose, Bradford D. Winters, Sridevi V. Sarma, Raimond L. Winslow
Summary: Hypoxemia is a major contributing factor to mortality in critically ill patients, including those with conditions like brain injury, cardiac arrest, and COVID-19. The SWIFT deep learning model can accurately predict blood oxygen saturation waveforms in the future, providing valuable information for clinical interventions and patient management.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Cell & Tissue Engineering
S. M. Ziauddin, Misako Nakashima, Hideto Watanabe, Michiyo Tominaga, Koichiro Iohara
Summary: This study compared the stem cell properties and pulp regenerative potential of DT-DPSCs and PT-DPSCs from the same individual. The results showed that DT-DPSCs exhibited higher expression of stem cell markers and angiogenic factors compared to PT-DPSCs. DT-DPSC-derived conditioned medium also promoted increased cell proliferation, migration, and angiogenesis. Furthermore, the regenerated pulp tissues in both DT-DPSCs and PT-DPSCs groups were similar. Therefore, DT-DPSCs could be a potential alternative to PT-DPSCs for pulp regenerative therapy.
STEM CELL RESEARCH & THERAPY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jiaqi Chen, Siyi Liu, Muqing Liu, Yanmei Dong
Summary: In this study, the outcomes of direct pulp capping (DPC) in mature permanent teeth with carious pulp exposure using iRoot BP Plus were evaluated. The results showed that long-term success is possible with DPC using iRoot BP Plus. Patient age and operator experience were identified as potential prognostic factors.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Runzhi Guo, Qianyao Yu, Yifan Lin, Jing Li, Yiping Huang, Weiran Li
Summary: For bimaxillary protrusion patients, the pulpal blood flow of the anterior teeth temporarily increases after orthodontic appliance removal and returns to non-orthodontic levels after 3 months. This effect is more pronounced in adolescent patients.
Article
Respiratory System
Brian Garnet, Rodrigo Diaz-Lankenau, Elie Jean, Michael Campos
Summary: This study evaluated the performance of SpO(2) compared to arterial blood gas analysis in detecting severe resting hypoxemia in patients with COPD. The results showed that using only SpO(2) as a measure of oxygenation had a high false negative rate, and it is recommended to use ABG analysis to evaluate oxygenation in these patients.
ANNALS OF THE AMERICAN THORACIC SOCIETY
(2023)
Article
Health Care Sciences & Services
Xiaoxu Guan, Yi Zhou, Qingxia Yang, Tianer Zhu, Xuepeng Chen, Shuli Deng, Denghui Zhang
Summary: Vital pulp therapy (VPT) with iRoot BP Plus in treating irreversible pulpitis caused by caries in 6-20-year-old patients showed a high success rate of 91.2% during 6-36 months of follow-up. The success rate remained high at 90.5% with an observation time of one year or more.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Medicine, General & Internal
Flavia Iaculli, Francisco Javier Rodriguez-Lozano, Benjamin Briseno-Marroquin, Thomas Gerhard Wolf, Gianrico Spagnuolo, Sandro Rengo
Summary: Vital pulp therapy (VPT) has been proposed as an alternative approach for symptomatic mature permanent teeth with deep caries lesions, aiming to maintain pulp vitality and avoid non-surgical root canal therapy. Pain assessment plays a key role in the success of VPT, and proper assessment of pulp inflammation and choice of appropriate materials are important factors for enhancing VPT success.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Dentistry, Oral Surgery & Medicine
Jessica Conti Reus, Helena Polmann, Beatriz Dulcineia Mendes Souza, Carlos Flores-Mir, Daniela Aparecida Godoi Goncalves, Luiz Paulo de Queiroz, Jeffrey Okeson, Graziela De Luca Canto
Summary: This systematic review examined the association between primary headaches (PHs) and temporomandibular disorders (TMDs) in adults. The study found a positive association between painful TMD and tension-type headache, migraines, and chronic headaches. However, no positive association was found between painless articular TMDs and tension-type headache or migraines. The certainty of evidence for the results varied between very low and low.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yadira V. Boza Oreamuno, Jessie F. Reyes-Carmona
Summary: This study analyzed the expression and spatial distribution of ALDH1A1, FGFR2, caspase-3, and CD44 in OSCC and leukoplakia. The results showed that FGFR2 and ALDH1A1 had significant differences in expression between OSCC and leukoplakia without dysplasia, suggesting that the presence of dysplasia is a significant clinic-pathologic predictor for malignant transformation.
ODOVTOS INTERNATIONAL JOURNAL OF DENTAL SCIENCES
(2023)
Review
Dentistry, Oral Surgery & Medicine
Ana Cristina Scremin Denardin, Luiza Pereira do Nascimento, Ligia Figueiredo Valesan, Cecilia Doebber Da Cas, Patricia Pauletto, Roberto Ramos Garanhani, Eduardo Januzzi, Leandro Augusto Hilgert, Beatriz Dulcineia Mendes de Souza
Summary: This study evaluated different guidance techniques in occlusal splints and found no sufficient evidence to support that any specific guidance could improve outcomes in temporomandibular disorder and sleep bruxism.
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Jessie Reyes-Carmona
Summary: A successful endodontic treatment requires satisfactory mechanical instrumentation, adequate irrigation protocols, and three-dimensional obturation. Sodium hypochlorite (NaOCl) is still considered the gold standard for irrigation. Recent evidence shows that irrigation protocols can cause erosion on radicular dentin. This article aims to describe the clinical features of the effect of irrigation protocols on radicular dentin.
ODOVTOS INTERNATIONAL JOURNAL OF DENTAL SCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Patricia da Agostim Cancelier, Renata Gondo Machado, Julia Menezes Savaris, Eduardo Antunes Bortoluzzi, Cleonice da Silveira Teixeira, Mariana Comparotto Minamisako, Paulo Marcelo Rodrigues, Vicente Ribeiro Netto, Kamile Leonardi Dutra-Horstmann, Lucas da Fonseca Roberti Garcia
Summary: This study investigated the effect of radiation timing on the bond strength of resin cement to intraradicular dentine. The results showed that radiation therapy after root canal treatment or after luting of a dental post significantly decreased the bond strength of resin cement.
AUSTRALIAN ENDODONTIC JOURNAL
(2023)
Article
Cell Biology
Cristina Retana-Lobo, Jessie Reyes-Carmona
Summary: This study evaluated the expression of differentiation markers in the apical papilla and dental pulp of human permanent teeth. The apical papilla had fewer vascular and cellular components compared to the dental pulp. STRO-1 and VEGFR-2 showed higher expression in the early and middle stages, while STRO-1 and NFH showed strong expression in the complete root length stage. Differentiated odontoblast and sub-odontoblastic cells expressed Nestin.
JOURNAL OF HISTOTECHNOLOGY
(2023)
Article
Engineering, Biomedical
Maybell Tedesco, Filipe Colombo Vitali, Eduardo Antunes Bortoluzzi, Lucas da Fonseca Roberti Garcia, Cleonice da Silveira Teixeira
Summary: This study evaluated the physicochemical properties of endodontic sealers containing dry or diluted rhodamine B. The results showed that dry rhodamine decreased bond strength and prolonged the setting time of AH Plus, while diluted rhodamine decreased setting time and increased flowability of MTA Fillapex. The incorporation of rhodamine also caused pH reductions in both sealers. Overall, diluted rhodamine changed the properties of MTA Fillapex, and dry rhodamine changed the properties of AH Plus.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Luiz Carlos de Lima Dias-Junior, Marcio Correa, Cleonice da Silveira Teixeira, Diego Leonardo de Souza, Franklin R. Tay, Carlos Estrela, Lucas da Fonseca Roberti Garcia, Eduardo Antunes Bortoluzzi
Summary: The present study developed a method to induce incomplete root fracture in human extracted teeth for evaluating different diagnostic imaging techniques. The method involved removing tooth crowns, preparing root canals, and applying a customized conical wedge with a specific force to induce fractures. The method was successful in producing fractures that resembled clinical presentation. It is a reproducible and reliable method for laboratory studies on vertical root fractures.
Article
Dentistry, Oral Surgery & Medicine
Sergio Murilo Coelho, Mariana Travi Pandolfo, Eduardo Antunes Bortoluzzi, Hebert Luis Rossetto, Roberta Pinto Pereira, Mariana Comparotto Minamisako, Paulo Marcelo Rodrigues, Vicente Ribeiro Netto, Tatiana da Silva Ramos, Cleonice da Silveira Teixeira, Lucas da Fonseca Roberti Garcia
Summary: This study aimed to evaluate the effect of radiation therapy on the fracture resistance of simulated immature teeth. The results showed that irradiated teeth had a lower fracture resistance compared to non-irradiated teeth. Reinforcement with fibreglass posts increased the fracture resistance, regardless of radiation.
INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY
(2023)
Review
Dentistry, Oral Surgery & Medicine
Filipe Colombo Vitali, Pablo Silveira Santos, Carla Massignan, Lucianne Cople Maia, Mariane Cardoso, Cleonice da Silveira Teixeira
Summary: This study aimed to determine the overall prevalence of maxillary sinusitis of odontogenic origin (MSOO) and verify associations between different odontogenic conditions and MSOO. The study found that the pooled prevalence of MSOO was 51% per maxillary sinus and 50% per patient. Apical lesion, periodontitis, and moderate and severe bone loss were significantly associated with MSOO.
JOURNAL OF ENDODONTICS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Filipe Colombo Vitali, Pablo Silveira Santos, Carla Massignan, Mariane Cardoso, Lucianne Cople Maia, Saul Martins Paiva, Cleonice da Silveira Teixeira
Summary: This study investigates the prevalence of natal and neonatal teeth worldwide. The results show that the prevalence of natal teeth is 34.55 per 10,000 and the prevalence of neonatal teeth is 4.52 per 10,000. The prevalence varies across continents, with Asia having the lowest prevalence and North America having the highest prevalence.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2023)
Review
Dentistry, Oral Surgery & Medicine
Amanda Freitas da Rosa, Bruna Venzke Fischer, Luiz Carlos de Lima Dias-Junior, Anna Victoria Costa Serique, Eduardo Antunes Bortoluzzi, Cleonice da Silveira Teixeira, Lucasda Fonseca Roberti Garcia
Summary: The aim of this study was to identify the most effective supplementary protocols used during endodontic reintervention for removing remaining filling material (FM). After a literature search and qualitative analysis of 46 articles, various supplementary protocols such as sonic and ultrasonic activation, ultrasonic inserts, and new devices were found to be effective in removing remaining FM, although complete removal was not always achieved. Combining these protocols can enhance FM removal and improve the cleaning and disinfection of root canals.
Review
Dentistry, Oral Surgery & Medicine
Rayssa Sabino-Silva, Ihan Vitor Cardoso, Filipe Colombo Vitali, Ana Maria Hecke Alves, Beatriz Dulcineia Mendes Souza, Eduardo Antunes Bortoluzzi, Lucas da Fonseca Roberti Garcia, Cleonice da Silveira Teixeira
Summary: This study investigated the prevalence of postoperative pain after endodontic treatment using low and high concentrations of sodium hypochlorite (NaOCl). The overall prevalence of postoperative pain was 45% in the low concentration group and 39% in the high concentration group.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Lucas Santos de Jesus, Tiago Lopes dos Santos Reis, Bernardo Guerra Mendonca de Melo Machado, Ana Luisa Monteiro da Costa', Julia Menezes Savaris, Claudia Angela Maziero Volpato, Eduardo Antunes Bortoluzzi, Cleonice da Silveira Teixeira, Paula Cristina dos Santos Vaz Fernandes, Lucas da Fonseca Roberti Garcia
Summary: This study aimed to assess the discoloration potential of hydraulic calcium silicate-based cements on dental structures, particularly on composite resin. The results showed that the cement induced significant discoloration on enamel/dentin and composite resin, with an increasing effect over time.
JOURNAL OF APPLIED ORAL SCIENCE
(2023)
Article
Dentistry, Oral Surgery & Medicine
Cristina Retana-Lobo, Tatiana Ramirez-Mora, Fabian Murillo-Gomez, Juliane Maria Guerreiro-Tanomaru, Mario Tanomaru-Filho, Jessie Reyes-Carmona
Summary: The effect of different final irrigation protocols on the microhardness, biochemical composition, and DMP1-CT expression of radicular dentin was evaluated. The results showed that certain protocols had detrimental effects on the expression, composition, and hardness of dentin.
CLINICAL ORAL INVESTIGATIONS
(2022)