期刊
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
卷 26, 期 5, 页码 416-423出版社
KARGER
DOI: 10.1159/000164797
关键词
Alzheimer's disease; Patient dependence; Costs of care, longitudinal changes
资金
- Elan Pharmaceuticals, Inc.
- Wyeth Pharmaceuticals
- Department of Veterans Affairs, Veterans Health Administration
- [R01 AG07370]
- [M01 RR000645]
- [U01AG010483]
- NATIONAL CENTER FOR RESEARCH RESOURCES [M01RR000645] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE ON AGING [R01AG007370, U01AG010483] Funding Source: NIH RePORTER
Background/Aims: To examine the incremental effect of patients' dependence on others, on cost of medical and non-medical care, and on informal caregiving hours over time. Methods: Data are obtained from 172 patients from the Predictors Study, a large, multicenter cohort of patients with probable Alzheimer disease (AD) followed annually for 4 years in 3 University-based AD centers in the USA. Enrollment required a modified Mini-Mental State Examination score >= 30. We examined the effects of patient dependence (measured by the Dependence Scale, DS) and function (measured by the Blessed Dementia Rating Scale, BDRS) on medical care cost, nonmedical care cost, and informal caregiving time using random effects regression models. Results: A one-point increase in DS score was associated with a 5.7% increase in medical cost, a 10.5% increase in nonmedical cost, and a 4.1% increase in caregiving time. A one-point increase in BDRS score was associated with a 7.6% increase in medical cost, a 3.9% increase in nonmedical cost and an 8.7% increase in caregiving time. Conclusions: Both functional impairment and patient dependence were associated with higher costs of care and caregiving time. Measures of functional impairment and patient dependence provide unique and incremental information on the overall impact of AD on patients and their caregivers. Copyright (C) 2008 S. Karger AG, Basel
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据