标题
N-Heterocyclic carbene metal complexes in medicinal chemistry
作者
关键词
-
出版物
DALTON TRANSACTIONS
Volume 42, Issue 10, Pages 3269-3284
出版商
Royal Society of Chemistry (RSC)
发表日期
2012-11-27
DOI
10.1039/c2dt32617e
参考文献
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- (2012) Malay Patra et al. CHEMBIOCHEM
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- (2012) Laure Eloy et al. ChemMedChem
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- (2011) J. G. Leid et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
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- (2009) C. L. Cannon et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
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- (2009) Khadijah M. Hindi et al. BIOMATERIALS
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- (2009) Ingo Ott COORDINATION CHEMISTRY REVIEWS
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- (2009) Jessica Lemke et al. DALTON TRANSACTIONS
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- (2009) Marie-Laure Teyssot et al. DALTON TRANSACTIONS
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- (2009) Sriparna Ray et al. JOURNAL OF ORGANOMETALLIC CHEMISTRY
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- (2007) Ulrike E. I. Horvath et al. NEW JOURNAL OF CHEMISTRY
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