Article
Pharmacology & Pharmacy
Aleen Khoury, Jennette A. Sakoff, Jayne Gilbert, Shawan Karan, Christopher P. Gordon, Janice R. Aldrich-Wright
Summary: Four platinum(IV) prodrugs incorporating a biotin moiety showed exceptional cytotoxicity against cancer cell lines. One of the prodrugs exhibited the lowest cytotoxicity in prostate cancer cells, while another prodrug showed higher activity in colon cancer cells. Some prodrugs also demonstrated selectivity towards breast cancer cells compared to healthy cells, which was not observed with their platinum(II) precursors.
Article
Chemistry, Inorganic & Nuclear
Paride Papadia, Alessandra Barbanente, Nicoletta Ditaranto, James D. Hoeschele, Giovanni Natile, Cristina Marzano, Valentina Gandin, Nicola Margiotta
Summary: Six enantiomerically pure, oxaliplatin-like platinum compounds with unsaturated cyclic diamine as a substitute for oxaliplatin were investigated for their promising antiproliferative activities, showing potential in overcoming resistance to platinum-based drugs. The R,R enantiomer was found to be most effective in Pt(ii) complexes while the S,S enantiomer showed greater efficacy in Pt(iv) derivatives, suggesting potential for further preclinical investigation.
DALTON TRANSACTIONS
(2021)
Article
Chemistry, Applied
Nicholas Wong, Eileen Zhao, Jiangyin Bao, Stefan G. Koenig, Carmela Molinaro, Jacob C. Timmerman, Haiming Zhang, C. Gregory Sowell, Francis Gosselin
Summary: Herein, we describe the evolution of synthesis of a single enantiomer of immuno-PET linker-chelator (1R,2R)-RESCA-TFP (1) from commercially available (1R,2R)-1,2-diaminocyclohexane. The syntheses involve reductive amination, trialkylation, saponification followed by EDCI-promoted TFP ester formation, and t-Bu ester global deprotection. The second-generation synthesis eliminates preparative purification operations by implementing salt formation and direct isolation by filtration.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2023)
Article
Biochemistry & Molecular Biology
Jana Hildebrandt, Norman Haefner, Helmar Goerls, Marie-Christin Barth, Matthias Duerst, Ingo B. Runnebaum, Wolfgang Weigand
Summary: Platinum(II) compounds have attracted significant attention in the development of anticancer drugs, with recent breakthroughs in structure-activity relationships. This study synthesized and characterized 17 complexes with beta-hydroxydithiocinnamic acid esters, revealing promising cytotoxic activity in palladium complexes against platinum-resistant tumors. The identified SARs may guide future research in targeting specific cancer cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Inorganic & Nuclear
Ayan Chakraborty, Souryadip Roy, Manas Pratim Chakraborty, Shantanu Saha Roy, Kallol Purkait, Tuhin Subhra Koley, Rahul Das, Moulinath Acharya, Arindam Mukherjee
Summary: Eight new ruthenium(II) complexes were synthesized and characterized, showing good solution stability and potential activity against hydrolysis and cytotoxicity. Additionally, these complexes have the ability to bind to DNA bases and inhibit the phosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2).
INORGANIC CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Antonino N. Fallica, Valeria Ciaffaglione, Maria N. Modica, Valeria Pittala, Loredana Salerno, Emanuele Amata, Agostino Marrazzo, Giuseppe Romeo, Sebastiano Intagliata
Summary: The overexpression of sigma receptors in tumors has prompted a deep investigation of their role in cancer pathophysiology. Sigma receptor ligands are gaining attention due to their potential as anticancer agents and imaging tracers.
BIOORGANIC & MEDICINAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Jana Hildebrandt, Norman Hafner, Daniel Kritsch, Helmar Goerls, Matthias Duerst, Ingo B. Runnebaum, Wolfgang Weigand
Summary: This study investigates the anticancer activity and resistance evasion ability of 17 ruthenium complexes and four osmium analogues with cinnamic acid derivatives as O,S bidentate ligands. The results show that these compounds exhibit high cancer cell selectivity and cytotoxicity without strong effects on DNA damage and cell cycle, suggesting another mode of action.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Inorganic & Nuclear
Wai-Hong Yu, Sze-Chun Yiu, Mei-Tung Lau, Po-Yu Ho, Pik-Ling Lam, Chung-Hin Chui, Wai-Yeung Wong
Summary: In this study, a series of neutral cyclometalated platinum(II) complexes were synthesized and their structural, photophysical, electrochemical, and aggregation induced emission (AIE) properties were systematically studied. One of the complexes showed bactericidal activity against Staphylococcus aureus (S. aureus) and methicillin-resistant S. aureus (MRSA) without noticeable cytotoxicity to human skin cells, suggesting its potential use for antibacterial therapy against S. aureus and MRSA-infected skin diseases.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Bojidarka Ivanova, Michael Spiteller
Summary: The study focuses on the crystallographic and theoretical electron density analyses of a zinc(II) bis((1R,2R)-1,2-diaminocyclohexane) dinitrate complex, revealing an atypical geometrical feature of the metal chromophore. It explores the diverse coordination modes of the ligand 1,2-diaminocyclohexane with transition metal ions and its potential in designing new metal-organic anticancer drugs. The research sheds light on the molecular and environmental factors influencing the observed geometry of the chromophore in the complex.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Multidisciplinary
Prateek Bhamboo, Anjali Sharma, S. S. Rithu Sai, Subhasree Sahoo, Dhananjoy Mondal, Smritilekha Bera
Summary: The enantioselective synthesis of (1R,2R)-chloramphenicol and its similar compounds was successfully achieved through the Evans asymmetric aldol reaction, with diastereoselectivity control of the reaction and transformation of aldol products into the clinically used chloramphenicol using a three-step method.
Article
Biochemistry & Molecular Biology
Zahra Shabaninejad, Maryam Nikkhah, S. Masoud Nabavizadeh
Summary: The DNA binding capacity and cytotoxic effects of two cycloplatinated complexes (C1 and C2) were evaluated. Both complexes exhibited high DNA binding affinity and were able to quench the fluorescence of ethidium bromide. They also induced DNA viscosity increase, confirming their intercalative interactions with DNA. C2 showed the highest cytotoxicity, particularly on a cisplatin resistant-cell line, and induced apoptosis comparable or higher than cisplatin in all cell lines.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Laia Rafols, Dana Josa, David Aguila, Leoni A. Barrios, Olivier Roubeau, Jordi Cirera, Vanessa Soto-Cerrato, Ricardo Perez-Tomas, Manuel Martinez, Arnald Grabulosa, Patrick Gamez
Summary: The newly synthesized compounds showed poor cytotoxic activities in cell cultures, but displayed improved activities in aged DMSO solutions. It was found that the compounds underwent transformation reactions in DMSO, ultimately forming cyclometalated species.
INORGANIC CHEMISTRY
(2021)
Review
Cell Biology
Nadya M. Morrow, Antonio A. Hanson, Erin E. Mulvihill
Summary: Enteroendocrine cells play a crucial role in regulating nutrient intake and disposal through the production and secretion of peptides. Understanding the identity of cells expressing Glp1r, Glp2r, and Gipr in different models can provide insights into dysregulation seen in obesity and diabetes. Further research on G-protein coupled receptor circuits in the intestine and their alterations with high-fat diet feeding is also important in understanding metabolic diseases.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Sophie A. Fitzgerald, Xiao Xiao, Jianzhang Zhao, Peter N. Horton, Simon J. Coles, Richard C. Knighton, Benjamin D. Ward, Simon J. A. Pope
Summary: A series of 2-phenylquinoxaline ligands with CF3 or OCF3 groups were synthesized and investigated as cyclometalating reagents for platinum(II). The resulting complexes displayed efficient visible absorption and orange-red photoluminescence, which could be tuned by the ligand. The complexes also showed good upconversion efficiencies as photosensitizers for triplet-triplet annihilation energy upconversion.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Alaa Elwan, Helmy Sakr, Abdel-Ghany A. El-Helby, Ahmed El-Morsy, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Mohamed El-Sherbiny, Khaled El-Adl
Summary: Sixteen [1, 2, 4]triazolo[4,3-a]quinoxalines were synthesized and evaluated for their anticancer activities as DNA intercalators and Topo II inhibitors. Compounds 7e, 7c, and 7b exhibited the highest anticancer activities and showed strong DNA affinities and Topo II inhibition.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Dale L. Ang, Celine Kelso, Jennifer L. Beck, Stephen F. Ralph, David G. Harman, Janice R. Aldrich-Wright
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
(2020)
Article
Chemistry, Applied
Christian Dankers, Joseph Tadros, David G. Harman, Janice R. Aldrich-Wright, Thanh Nguyen, Christopher P. Gordon
ACS COMBINATORIAL SCIENCE
(2020)
Article
Chemistry, Organic
Maria Menti-Platten, Janice R. Aldrich-Wright, Christopher P. Gordon
Summary: Orthogonal deprotection methodologies are an important tool for modifying peptides. The researchers have developed a method using Pd/CaCO3 to selectively remove a specific protecting group from peptide sequences.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Pharmacology & Pharmacy
Aleen Khoury, Jennette A. Sakoff, Jayne Gilbert, Kieran F. Scott, Shawan Karan, Christopher P. Gordon, Janice R. Aldrich-Wright
Summary: Platinum(IV) prodrugs showed outstanding activity against various cancer cell lines, with nanomolar activities observed. Cellular accumulation of the complexes was correlated with increased cytotoxicity. COX inhibition or lipophilicity did not solely determine the cytotoxicity of these prodrugs.
Article
Biochemistry & Molecular Biology
Brondwyn S. McGhie, Janice R. Aldrich-Wright
Summary: Cancer is responsible for over 9 million deaths worldwide each year. Current treatment options have low success rates, especially for late-stage cancers. Researchers globally are continuously searching for alternative treatment options. This study focuses on innovations in inorganic anticancer therapies with photoactive and luminescent properties. Transition metals offer advantages in both chemotherapeutics and luminescence. The study explores the effects of structural changes on the properties and the use of inherent luminescent properties for monitoring cellular localization in photodynamic therapy.
Article
Biochemistry & Molecular Biology
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Summary: The DNA-alkylating derivative chlorambucil was coordinated with atypical cytotoxic platinum(IV) complexes, resulting in prodrugs with remarkable antitumor potential. The prodrug 56CLB showed exceptionally high activity in multiple cancer cell lines and induced significant production of reactive oxygen species in treated cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Brondwyn S. McGhie, Jennette Sakoff, Jayne Gilbert, Christopher P. Gordon, Janice R. Aldrich-Wright
Summary: This paper describes the development of novel quadruplex DNA-stabilizing metal complexes and demonstrates their stability-enhancing effects on quadruplex DNA. Furthermore, these complexes exhibit cytotoxic effects and show good selectivity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Summary: A new series of cytotoxic platinum(IV) complexes incorporating halogenated phenylacetic acid derivatives were synthesized and evaluated for their biological activity. The results showed that two of the complexes exhibited superior cytotoxicity, with one of them being significantly more potent than cisplatin and the lead complex in a prostate cancer cell line. Further studies were conducted to analyze the physicochemical properties and reactive oxygen species production of the complexes.
Article
Pharmacology & Pharmacy
Aleen Khoury, Jennette A. Sakoff, Jayne Gilbert, Shawan Karan, Christopher P. Gordon, Janice R. Aldrich-Wright
Summary: Four platinum(IV) prodrugs incorporating a biotin moiety showed exceptional cytotoxicity against cancer cell lines. One of the prodrugs exhibited the lowest cytotoxicity in prostate cancer cells, while another prodrug showed higher activity in colon cancer cells. Some prodrugs also demonstrated selectivity towards breast cancer cells compared to healthy cells, which was not observed with their platinum(II) precursors.
Article
Biochemistry & Molecular Biology
Brondwyn S. McGhie, Jennette Sakoff, Jayne Gilbert, Christopher P. Gordon, Janice R. Aldrich-Wright
Summary: Cancer is a significant global health threat and new treatments are needed to improve patient prognosis. Unconventional platinum complexes, consisting of polypyridyl ligands and diaminocyclohexane, have shown anticancer activity in previously undruggable KRAS mutated cells, with cytotoxicity values up to 100 times better than cisplatin. Inspired by these complexes, six novel cyclometallated examples were designed and their fluorescence was used to study the mechanism of action of platinum drugs. The cytotoxicity results showed that these cyclometallated complexes have different activity compared to the inspiring complexes, but are as cytotoxic as cisplatin and have higher selectivity indices in breast cancer cell lines. Complexes 1b, 2a, and 3b exhibited particularly high selectivity indexes. Further investigation revealed their good affinity to ctDNA, especially CMCs 1a and 3b. The fluorescence of these complexes was successfully utilized in calculating their DNA binding affinity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Medicinal
Hana Kostrhunova, Brondwyn S. McGhie, Lenka Markova, Olga Novakova, Jana Kasparkova, Janice R. Aldrich-Wright, Viktor Brabec
Summary: The platinum(II) complex Pt(II)56MeSS exhibits high potency against cancer cells but also displays side toxicity and in vivo activity. The synthesis of new platinum(IV) prodrugs combining Pt(II)56MeSS with diclofenac (DCF) is described. These Pt(IV) complexes show similar mechanisms of action as Pt(II)56MeSS and DCF, promoting antiproliferative activity and inducing cell death and immunogenic cell death in cancer cells.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Oncology
Angelico D. Aputen, Maria George Elias, Jayne Gilbert, Jennette A. Sakoff, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich-Wright
Summary: The development of new and versatile platinum(IV) complexes is a rapidly evolving research strategy for cancer drug discovery. In this study, platinum(IV) complexes conjugated with non-steroidal anti-inflammatory molecules were synthesized and showed significantly improved anti-tumor potential compared to traditional platinum(II) chemotherapy drugs. These complexes also demonstrated the ability to reduce cellular and mitochondrial activity, decrease cancer cell resistance to chemotherapy, and inhibit COX-2 enzyme, thereby reducing inflammation in cancer cells.
Article
Chemistry, Multidisciplinary
Aleksandra Bjelosevic, Jennette Sakoff, Jayne Gilbert, Yingjie Zhang, Christopher Gordon, Janice R. Aldrich-Wright
AUSTRALIAN JOURNAL OF CHEMISTRY
(2020)
Article
Chemistry, Inorganic & Nuclear
Li Li, Alexander R. Craze, Outi Mustonen, Hikaru Zenno, Jacob J. Whittaker, Shinya Hayami, Leonard F. Lindoy, Christopher E. Marjo, Jack K. Clegg, Janice R. Aldrich-Wright, Feng Li
DALTON TRANSACTIONS
(2019)
Article
Chemistry, Multidisciplinary
Lawson K. Spare, Maria Menti, David G. Harman, Janice R. Aldrich-Wright, Christopher P. Gordon
REACTION CHEMISTRY & ENGINEERING
(2019)
Article
Chemistry, Inorganic & Nuclear
Vaibhav Bedi, Dipendu Mandal, Zahid Hussain, Shi-Ming Chen, Yile Wu, Zheng-Wang Qu, Stefan Grimme, Douglas W. Stephan
Summary: The reaction of (tBuO(2)CN)(2) with 9-BBN leads to the formation of a bicyclic heterocyclic compound, while its reactions with BF3 or [Et3Si][B(C6F5)(4)] result in the isolation of different compounds. Computational studies reveal that the steric and electronic properties of the Lewis acid are important in the formation of one of the compounds.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Chisa Itoh, Haruka Yoshino, Taku Kitayama, Wataru Kosaka, Hitoshi Miyasaka
Summary: A new synthetic route for constructing functional paddlewheel diruthenium(II,II) complexes was developed, utilizing Schiff base condensation reactions. The attached Schiff base groups significantly affected the electronic states of the resulting complexes, as revealed by cyclic voltammetry and DFT calculations.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Danrui Ni, Haozhe Wang, Xianghan Xu, Weiwei Xie, Robert J. Cava
Summary: A layered rhombohedral polymorph of indium(iii) triiodide is synthesized at high pressure and temperature. It has an orange color, which is different from ambient pressure InI3, which has a monoclinic molecular structure and a light-yellow color.
DALTON TRANSACTIONS
(2024)
Review
Chemistry, Inorganic & Nuclear
Juan Carlos Perez-Sanchez, Raquel P. Herrera, M. Concepcion Gimeno
Summary: Gold(II) complexes have been less utilized in catalysis compared to their gold(I) and gold(III) counterparts. However, gold(II) complexes offer potential in homo-coupling and cross-coupling reactions, as they are more easily accessible through simplified oxidation and reduction processes. Gold(II) exhibits characteristics of both soft acid gold(I) and hard acid gold(III). This review explores the unique reactivity and potential applications of gold(II) species, highlighting their significance in catalytic transformations.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Nighat Yousuf, Yanping Ma, Qaiser Mahmood, Wenjuan Zhang, Yizhou Wang, Hassan Saeed, Wen-Hua Sun
Summary: In this study, a series of structurally rigid cyclooctyl-fused iminopyridine iron complexes were synthesized and used with methylaluminoxane for isoprene polymerization. The extent of steric hindrance of the ligand framework was found to significantly affect catalytic performance, with less hindrance leading to better activity and stability.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Chenghao Song, Huiwei Du, Menglei Xu, Jie Yang, Xinyu Zhang, Jungan Wang, Yuanfang Zhang, Chengjun Gu, Rui Li, Tao Hong, Jingji Zhang, Jiangying Wang, Yongchun Ye
Summary: This study improves the performance of perovskite solar cells by using a dual-hole transport layer strategy. This strategy enhances the charge transfer efficiency of the transport layer, reduces charge recombination, and improves the quality of the perovskite film layer. Ultimately, the stability of the device is enhanced.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Mahender Singh, Aakash Yadav, Ranjit Singh, Chullikkattil P. Pradeep
Summary: A new aryl selenonium polyoxometalate hybrid was developed and compared with an aryl sulfonium polyoxometalate hybrid in terms of their photocatalytic properties. It was found that the aryl selenonium hybrid exhibited better catalytic performance, which could be attributed to the larger atomic radii of selenium stabilizing the photogenerated electron-hole pair more efficiently. Additionally, the generation of elemental selenium through cleavage of C-Se bonds during catalysis was observed.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Yuhan Xie, Boyu Dong, Xuemin Wang, Siyuan Wang, Jinxi Chen, Yongbing Lou
Summary: This study successfully fabricated visible-light-responsive three-dimensional core-shell CoSe2/ZnIn2S4 heterostructures and achieved attractive activity in photocatalytic hydrogen evolution. The presence of CoSe2 improved light absorption and accelerated charge transfer kinetics. The strong interaction between CoSe2 and ZnIn2S4 reduced charge recombination, further enhancing photocatalytic activity for hydrogen evolution.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Andre L. de O. Batista, Joao Marcos T. Palheta, Mauricio J. Piotrowski, Celso R. C. Rego, Diego Guedes-Sobrinho, Alexandre C. Dias
Summary: This study presents a simulation protocol that provides a solid foundation for exploring two-dimensional materials. Using the TiBr2 2H monolayer as an example, the study reveals its promising properties for optoelectronic and valleytronic applications, including its stability, spin-orbit coupling effects, and optical helicity selection rule.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Jiang Jiang, Zi-Wei Li, Zhi-Zhuan Zhang, Bin Tan, Zhao-Feng Wu, Xiao-Ying Huang
Summary: In this work, two metal organic frameworks (MOFs) containing {Cu2I2} clusters, Eu-CuI-INA and Sr-K-CuI-INA, were synthesized and characterized. Both materials have a three-dimensional structure with {Cu2I2} clusters coordinated by INA(-) ligands and Eu3+ or Sr2+ ions. The Sr-K-CuI-INA material exhibited sensitive fluorescence sensing behaviors towards cysteine and nitro-bearing molecules, showing potential applications in bio and explosive molecule sensing. This work provides a good reference for designing fluorescent MOF probes containing CuI molecules.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Zhiya Lin, Jiasheng Wu, Qianwen Ye, Yulong Chen, Hai Jia, Xiaohui Huang, Shaoming Ying
Summary: Na-ion batteries (NIBs) have attracted great interest as a potential technology for grid-scale energy storage due to the wide distribution, low cost, and environmental friendliness of sodium resources. However, their implementation is hindered by low rate capability and cycling stability caused by the large ionic size of Na+. In this study, a three-dimensional nanoarchitectured coral-like CoSe2@N-doped carbon (CL-CoSe2@NC) was synthesized, and it exhibited improved sodium storage properties with better electrode kinetics and a stable SEI film.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Ya-Qiong Zhang, Yu Zhang, Guoping Zeng, Rong-Zhen Liao, Man Li
Summary: The mechanism and selectivity of CO2 reduction under visible light were investigated using density functional calculations. The results showed that a tetradentate PNNP-type Iridium(III) complex exhibited high activity and selectivity in the reaction.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Sanyukta Ghosh, Shubhanth Jain, Soumya Ranjan Mishra, Gerda Rogl, Peter Rogl, Ernst Bauer, B. S. Murty, A. Govindaraj, Ramesh Chandra Mallik
Summary: In this study, reduced graphene oxide (rGO) was uniformly dispersed in the In0.5Co4Sb12 bulk material by ultrasonication, which effectively reduced the lattice thermal conductivity and improved the thermoelectric efficiency.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Mika Takeuchi, Yutaka Amao
Summary: This study developed an effective visible-light driven system for fumaric acid production using renewable resources such as biomass derivatives, providing an alternative to the current petroleum-based synthesis methods.
DALTON TRANSACTIONS
(2024)
Article
Chemistry, Inorganic & Nuclear
Juan Jian, Meiting Wang, Zhuo Wang, Jingwen Meng, Yuqin Yang, Limin Chang
Summary: Developing low-cost and self-supported bifunctional catalysts is crucial for highly efficient water splitting devices. In this study, nano-NiFe2O4 was directly grown onto iron foil surface and Sn4+ was introduced into the NiFe2O4. The resulting Sn-NiFe2O4/IF showed low overpotentials and high current densities during oxygen evolution reaction (OER) and hydrogen evolution reaction (HER), making it a promising catalyst for large-scale hydrogen production.
DALTON TRANSACTIONS
(2024)