Bisphosphonate metal complexes as selective inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase

Update in treatment of Chagas disease

(2011) Guillaume Le Loup et al.   CURRENT OPINION IN INFECTIOUS DISEASES

New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents

(2011) Bruno Demoro et al.   DALTON TRANSACTIONS

Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry

(2011) Artur Mucha et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting Isoprenoid Biosynthesis for Drug Discovery: Bench to Bedside

(2010) Eric Oldfield   ACCOUNTS OF CHEMICAL RESEARCH

Biochemical and molecular mechanisms of action of bisphosphonates

(2010) Michael J. Rogers et al.   BONE

Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

(2010) Maribel Navarro et al.   DRUG DISCOVERY TODAY

Risedronate metal complexes potentially active against Chagas disease

(2010) Bruno Demoro et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Chagas disease

(2010) Anis Rassi et al.   LANCET

In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds

(2010) Adriana M. C. Canavaci et al.   PLoS Neglected Tropical Diseases

Specific chemotherapy of Chagas disease: Relevance, current limitations and new approaches

(2009) Julio A. Urbina   ACTA TROPICA

Chagas disease: A Latin American health problem becoming a world health problem

(2009) Gabriel A. Schmunis et al.   ACTA TROPICA

New Therapeutic Targets for Drug Design Against Trypanosoma cruzi, Advances and Perspectives

(2009) Gildardo Rivera et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action

(2009) Marisol Vieites et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The Acidocalcisome as a Target for Chemotherapeutic Agents in Protozoan Parasites

(2008) Roberto Docampo et al.   CURRENT PHARMACEUTICAL DESIGN

Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite-specific fumarate reductase

(2008) Marisol Vieites et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Metal compounds for the treatment of parasitic diseases

(2008) Simon P. Fricker et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Design of vanadium mixed-ligand complexes as potential anti-protozoa agents

(2008) Julio Benítez et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Platinum-based complexes of bioactive 3-(5-nitrofuryl)acroleine thiosemicarbazones showing anti-Trypanosoma cruzi activity

(2008) Marisol Vieites et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Structure–Activity Relationships Among the Nitrogen Containing Bisphosphonates in Clinical Use and Other Analogues: Time-Dependent Inhibition of Human Farnesyl Pyrophosphate Synthase

(2008) James E. Dunford et al.   JOURNAL OF MEDICINAL CHEMISTRY

Spectroscopic and DFT study of 3-quinolyl-α-aminophosphonates

(2008) Marina Juribašić et al.   JOURNAL OF MOLECULAR STRUCTURE

Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents

(2007) Marisol Vieites et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

ESR, electrochemical and reactivity studies of antitrypanosomal palladium thiosemicarbazone complexes

(2007) Lucía Otero et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY