Rab8 GTPase as a regulator of cell shape

Identification and characterisation of novel Mss4-binding Rab GTPases

(2011) Viktor Wixler et al.   BIOLOGICAL CHEMISTRY

Rab6, Rab8, and MICAL3 Cooperate in Controlling Docking and Fusion of Exocytotic Carriers

(2011) Ilya Grigoriev et al.   CURRENT BIOLOGY

A structural basis for Lowe syndrome caused by mutations in the Rab-binding domain of OCRL1

(2011) Xiaomin Hou et al.   EMBO JOURNAL

Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration

(2011) Zhizhan Gu et al.   JOURNAL OF CELL BIOLOGY

Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures

(2011) Anette Pykäläinen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Screening of OPTN in French familial amyotrophic lateral sclerosis

(2011) Stéphanie Millecamps et al.   NEUROBIOLOGY OF AGING

Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome

(2011) C. J. Westlake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization

(2011) J. T. Roland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virus Entry by Endocytosis

(2010) Jason Mercer et al.   Annual Review of Biochemistry

R-Ras regulates β1-integrin trafficking via effects on membrane ruffling and endocytosis

(2010) Matthew W Conklin et al.   BMC CELL BIOLOGY

Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant

(2010) Ananthamurthy Nagabhushana et al.   BMC CELL BIOLOGY

The fast and slow ups and downs of HCN channel regulation

(2010) Alan S. Lewis et al.   Channels

Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration

(2010) C. A. Murga-Zamalloa et al.   HUMAN MOLECULAR GENETICS

Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice

(2010) Zai-Long Chi et al.   HUMAN MOLECULAR GENETICS

Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model

(2010) Frank M. Ruemmele et al.   HUMAN MUTATION

Collapsin Response Mediator Protein-2 (Crmp2) Regulates Trafficking by Linking Endocytic Regulatory Proteins to Dynein Motors

(2010) Juliati Rahajeng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab8 Interacts with Distinct Motifs in α2B- and β2-Adrenergic Receptors and Differentially Modulates Their Transport

(2010) Chunmin Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

(2010) Shin-ichiro Yoshimura et al.   JOURNAL OF CELL BIOLOGY

Cdc42 localization and cell polarity depend on membrane traffic

(2010) Naël Osmani et al.   JOURNAL OF CELL BIOLOGY

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence

(2010) John A. Follit et al.   JOURNAL OF CELL BIOLOGY

Differential role of Rab proteins in ciliary trafficking: Rab23 regulates Smoothened levels

(2010) C. Boehlke et al.   JOURNAL OF CELL SCIENCE

Retinal Degeneration and Failure of Photoreceptor Outer Segment Formation in Mice with Targeted Deletion of the Joubert Syndrome Gene, Ahi1

(2010) J. E. Westfall et al.   JOURNAL OF NEUROSCIENCE

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

(2010) A. Sakurai et al.   MOLECULAR AND CELLULAR BIOLOGY

Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane

(2010) Lisa M. Bond et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations of optineurin in amyotrophic lateral sclerosis

(2010) Hirofumi Maruyama et al.   NATURE

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

Impairment of Protein Trafficking upon Overexpression and Mutation of Optineurin

(2010) BumChan Park et al.   PLoS One

RhoA Regulates Peroxisome Association to Microtubules and the Actin Cytoskeleton

(2010) Lukas Schollenberger et al.   PLoS One

Coordination of Rab8 and Rab11 in primary ciliogenesis

(2010) A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells

(2010) Y. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GTPases involved in vesicular trafficking: Structures and mechanisms

(2010) Aymelt Itzen et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Myosin VI and Optineurin Are Required for Polarized EGFR Delivery and Directed Migration

(2010) Margarita V. Chibalina et al.   TRAFFIC

Rab8 Regulates ABCA1 Cell Surface Expression and Facilitates Cholesterol Efflux in Primary Human Macrophages

(2009) Matts D. Linder et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The primary cilium as a cellular signaling center: lessons from disease

(2009) Madeline A Lancaster et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Ahi1, whose human ortholog is mutated in Joubert syndrome, is required for Rab8a localization, ciliogenesis and vesicle trafficking

(2009) Yi-Chun Hsiao et al.   HUMAN MOLECULAR GENETICS

Myosin Vc, a Member of the Actin Motor Family Associated with Rab8, Is Involved in the Release of DV2 from HepG2 Cells

(2009) Xiao-Feng Xu et al.   INTERVIROLOGY

Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy

(2009) Norann A. Zaghloul et al.   JOURNAL OF CLINICAL INVESTIGATION

Negative Guidance Factor-Induced Macropinocytosis in the Growth Cone Plays a Critical Role in Repulsive Axon Turning

(2009) A. L. Kolpak et al.   JOURNAL OF NEUROSCIENCE

Myosin Vc Is a Molecular Motor That Functions in Secretory Granule Trafficking

(2009) Damon T. Jacobs et al.   MOLECULAR BIOLOGY OF THE CELL

Mutant Huntingtin Impairs Post-Golgi Trafficking to Lysosomes by Delocalizing Optineurin/Rab8 Complex from the Golgi Apparatus

(2009) Daniel del Toro et al.   MOLECULAR BIOLOGY OF THE CELL

EphA2 Engages Git1 to Suppress Arf6 Activity Modulating Epithelial Cell–Cell Contacts

(2009) Koichi Miura et al.   MOLECULAR BIOLOGY OF THE CELL

MICAL-L1 Links EHD1 to Tubular Recycling Endosomes and Regulates Receptor Recycling

(2009) Mahak Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ARF6-Mediated Endosome Recycling Reverses Lipid Accumulation Defects in Niemann-Pick Type C Disease

(2009) Jill Kuglin Schweitzer et al.   PLoS One

Membrane Organization and Dynamics in Cell Polarity

(2009) K. Orlando et al.   Cold Spring Harbor Perspectives in Biology

Remodeling Epithelial Cell Organization: Transitions Between Front-Rear and Apical-Basal Polarity

(2009) W. J. Nelson   Cold Spring Harbor Perspectives in Biology

Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation

(2008) Shuhei Ishikura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Clathrin-independent endocytosis: A unique platform for cell signaling and PM remodeling

(2008) J DONALDSON et al.   CELLULAR SIGNALLING

CP110 Suppresses Primary Cilia Formation through Its Interaction with CEP290, a Protein Deficient in Human Ciliary Disease

(2008) William Y. Tsang et al.   DEVELOPMENTAL CELL

Rab8b GTPase, a protein transport regulator, is an interacting partner of otoferlin, defective in a human autosomal recessive deafness form

(2008) P. Heidrych et al.   HUMAN MOLECULAR GENETICS

CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium

(2008) Joon Kim et al.   HUMAN MOLECULAR GENETICS

GLUT4 Vesicle Recruitment and Fusion Are Differentially Regulated by Rac, AS160, and Rab8A in Muscle Cells

(2008) Varinder K. Randhawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Splicing in Class V Myosins Determines Association with Rab10

(2008) Joseph T. Roland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab8 Regulates Basolateral Secretory, But Not Recycling, Traffic at the Recycling Endosome

(2008) Lauren Henry et al.   MOLECULAR BIOLOGY OF THE CELL

elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

(2008) Yoshihiro Omori et al.   NATURE CELL BIOLOGY

MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity

(2008) Thomas Müller et al.   NATURE GENETICS

Rab8 is Involved in Zymogen Granule Formation in Pancreatic Acinar AR42J Cells

(2008) Floriane Faust et al.   TRAFFIC

Roles for the recycling endosome, Rab8, and Rab11 in hantavirus release from epithelial cells

(2008) Regina K. Rowe et al.   VIROLOGY

The Interaction of JRAB/MICAL-L2 with Rab8 and Rab13 Coordinates the Assembly of Tight Junctions and Adherens Junctions

(2007) Rie Yamamura et al.   MOLECULAR BIOLOGY OF THE CELL