Article
Allergy
Ralf Baumann, Eva Untersmayr, Ulrich M. Zissler, Stefanie Eyerich, Ian M. Adcock, Knut Brockow, Tilo Biedermann, Markus Ollert, Adam M. Chaker, Oliver Pfaar, Holger Garn, Ryan S. Thwaites, Alkis Togias, Marek L. Kowalski, Trevor T. Hansel, Constanze A. Jakwerth, Carsten B. Schmidt-Weber
Summary: Allergic diseases are increasing, and local sampling methods can improve sensitivity, reduce costs, and aid in prevention and treatment.
Review
Nutrition & Dietetics
Alexandru Cosmin Pantazi, Cristina Maria Mihai, Adriana Luminita Balasa, Tatiana Chisnoiu, Ancuta Lupu, Corina Elena Frecus, Larisia Mihai, Adina Ungureanu, Mustafa Ali Kassim Kassim, Antonio Andrusca, Maria Nicolae, Viviana Cuzic, Vasile Valeriu Lupu, Simona Claudia Cambrea
Summary: The intestinal microbiota is a diverse and complex microecosystem that stabilizes by the age of three and plays a crucial role in human health, particularly in early childhood. Dysbiosis has been linked to the development of allergic diseases, such as atopic dermatitis, asthma, and food allergies. Next-generation sequencing methods have improved our understanding of the relationship between dysbiosis and allergic diseases. This review paper aims to synthesize the current knowledge on the development of the intestinal microbiota, its long-term impact on health, and the connection between dysbiosis and allergic diseases, as well as interventions for prevention and treatment.
Review
Allergy
Sayantani B. Sindher, Andrew Long, Andrew R. Chin, Angela Hy, Vanitha Sampath, Kari C. Nadeau, R. Sharon Chinthrajah
Summary: The incidence of food allergy is increasing, and significant advancements have been made in the diagnosis, prevention, and treatment of FA. Highly sensitive assays and early intervention have been studied to decrease the risk of FA. Additionally, there has been a rise in clinical trials for innovative therapeutic strategies aimed at treating FA.
Review
Immunology
Carlo Maria Rossi, Marco Vincenzo Lenti, Stefania Merli, Giovanni Santacroce, Antonio Di Sabatino
Summary: Allergic disorders are increasing in young people and are associated with significant disease burden. The altered immune system response in the gut is recognized as a relevant step in the pathogenesis of these disorders. Allergic disorders have a high prevalence in gastrointestinal autoimmune diseases, and comprehensive care for autoimmune gastrointestinal disorders should include evaluation and treatment of allergic disorders.
AUTOIMMUNITY REVIEWS
(2022)
Review
Food Science & Technology
Hanieh Malmir, Bagher Larijani, Ahmad Esmaillzadeh
Summary: This meta-analysis found that maternal fish consumption during pregnancy is associated with a lower risk of wheeze, eczema, and food allergy in children. However, there is no significant association between maternal fish consumption and the risk of offspring's asthma, allergic rhinitis, and inhalant allergy.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Chemistry, Multidisciplinary
Ignacio Esteban-Gorgojo, Manuel Jorge Rial, Joaquin Sastre
Summary: This study analyzed the relationship between eosinophilia and asthma, finding that eosinophilia is associated with rhinitis, atopy, and decreased lung function, specifically in persistent asthma.
APPLIED SCIENCES-BASEL
(2022)
Review
Allergy
Samidi Navaratna, Marie J. Estcourt, John Burgess, Nilakshi Waidyatillake, Elizabeth Enoh, Adrian J. Lowe, Rachel Peters, Jennifer Koplin, Shyamali C. Dhamage, Caroline J. Lodge
Summary: The study found that childhood vaccination with commonly administered vaccines was not associated with increased risk of later allergic disease. Vaccination with BCG and measles vaccines were associated with a reduced risk of eczema.
Article
Immunology
Tiago Azenha Rama, Diana Martins, Nuno Gomes, Jorge Pinheiro, Ana Nogueira, Luis Delgado, Jose Luis Placido, Alice Coimbra
Summary: Mastocytosis is a rare and heterogeneous group of disorders characterized by expansion and accumulation of clonal mast cells, presenting mainly with cutaneous lesions and anaphylaxis. Due to its unusual features, the diagnosis of mastocytosis may be delayed for several years.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Environmental Sciences
Abigail Gaylord, Emily S. Barrett, Sheela Sathyanarayana, Shanna H. Swan, Ruby H. N. Nguyen, Nicole R. Bush, Kecia Carroll, Drew B. Day, Kurunthachalam Kannank, Leonardo Trasande
Summary: This study investigated the influence of prenatal exposure to the endocrine disrupting chemical bisphenol A on childhood atopic disease. The results showed that there were inverse associations between first trimester bisphenol A concentration and food allergy, while second trimester bisphenol A concentration was positively associated with food allergy. Additionally, prenatal exposure to bisphenol S was found to increase the risk of asthma among males.
ENVIRONMENTAL RESEARCH
(2023)
Review
Nutrition & Dietetics
Anna Debinska, Barbara Sozanska
Summary: The global prevalence of allergic diseases and asthma has significantly increased in the last few decades. Diet has been hypothesized to be an important immunomodulatory factor influencing susceptibility to these diseases. Fermented food, as a natural source of living microorganisms and bioactive compounds, has been shown to have health-promoting potentials and is considered a promising strategy to reduce the risk of immune-related diseases such as allergic diseases and asthma.
Article
Allergy
Isabel J. Skypala, Hannah Hunter, Mamidipudi Thirumala Krishna, Helena Rey-Garcia, Stephen J. Till, George du Toit, Elizabeth Angier, Sarah Baker, Kostadin V. Stoenchev, David K. Luyt
Summary: Pollen food syndrome (PFS) is a common food allergy caused by the homology between pollen allergens and proteins in certain foods. Diagnosing PFS can usually be done based on clinical history, but additional tests may be needed in some cases. Management involves avoiding trigger foods, which can be challenging for individuals with other food allergies or those on a vegetarian/vegan diet. Currently, there is no effective treatment for PFS, but oral or sublingual immunotherapy may hold promise.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Allergy
Lucy E. Bradshaw, Laura A. Wyatt, Sara J. Brown, Rachel H. Haines, Alan A. Montgomery, Michael R. Perkin, Sandra Lawton, Tracey H. Sach, Joanne R. Chalmers, Matthew J. Ridd, Carsten Flohr, Joanne Brooks, Richard Swinden, Eleanor J. Mitchell, Stella Tarr, Nicola Jay, Kim S. Thomas, Hilary Allen, Michael J. Cork, Maeve M. Kelleher, Eric L. Simpson, Stella T. Lartey, Susan Davies-Jones, Robert J. Boyle, Hywel C. Williams
Summary: The study found that daily emollient application during the first year of life does not prevent atopic dermatitis, food allergy, asthma, or hay fever. The difference in incidence rates of atopic dermatitis, food allergy, asthma, and hay fever between the emollient group and the control group was relatively small.
Article
Allergy
Peter Schmid-Grendelmeier, Melinda J. Gooderham, Karin Hartmann, George N. Konstantinou, Marc Fellmann, Christopher Koulias, Claire Clibborn, Pinaki Biswas, Patrick M. Brunner
Summary: This article evaluated the efficacy and safety of abrocitinib in patients with moderate-to-severe atopic dermatitis and allergic comorbidities. The results showed that abrocitinib was effective and safe in managing atopic dermatitis in patients with or without allergic comorbidities.
Review
Nutrition & Dietetics
Anna Debinska, Barbara Sozanska
Summary: This review discusses the potential anti-allergic actions of dietary polyphenols, including their ability to reduce protein allergenicity, regulate immune response, and modify gut microbiome. It reviews current evidence that various polyphenols can attenuate allergic inflammation and alleviate symptoms of allergic diseases. It suggests that dietary polyphenols have great anti-allergic potential and could be used for preventive or therapeutic interventions.
Review
Immunology
Haocheng Zheng, Yi Zhang, Jiachuang Pan, Nannan Liu, Yu Qin, Linghui Qiu, Min Liu, Tieshan Wang
Summary: Allergic diseases have been on the rise due to environmental changes and social development, leading to a significant public health burden. Recent studies suggest that ILC2s play important roles in allergic diseases, but further research is needed to fully understand their impact and potential treatment avenues.
FRONTIERS IN IMMUNOLOGY
(2021)
