Article
Environmental Studies
Syed Abdul Rehman Khan, Zhang Yu, Arshian Sharif
Summary: In a panel of European Union (EU) member states, this study examined the impact of green supply chain management practices on environmental sustainability and economic growth. The findings suggest that green supply chain practices play a positive role in reducing pollution, improving environmental quality, and attracting foreign investors.
Editorial Material
Computer Science, Hardware & Architecture
David Alan Grier
Summary: Throughout its existence, Computer has been at the center of discussion over how software should be engineered and developed. No article has been more central to this discussion than Frederick P. Brooks' No Silver Bullet.
Review
Plant Sciences
Ying Wu, William Sexton, Bing Yang, Shunyuan Xiao
Summary: Nonhost resistance (NHR) in plants refers to the immunity of most tested genotypes of a plant species against most tested variants of a pathogen species. NHR is a broad spectrum and durable defense mechanism that serves as a major barrier against potentially pathogenic microbes invading plants. Through genetic studies, researchers have made significant progress in understanding the molecular basis of NHR, which includes pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity. This review discusses the challenges in genetic studies of NHR and summarizes the approaches used to identify genes contributing to NHR, with a focus on dissecting multilayered NHR in model plants against filamentous pathogens.
MOLECULAR PLANT PATHOLOGY
(2023)
Article
Engineering, Industrial
Edgar Brea, Jerad A. Ford
Summary: This study investigates whether different learning modes and knowledge integration mechanisms result in different innovation outcomes from cognitive technology use. The findings show that scientific and technology-based innovation firms benefit significantly, while service-based firms only achieve incremental innovations.
Article
Ecology
Kamal Thapa, Natalie Schmitt, Narendra M. B. Pradhan, Hem Raj Acharya, Santosh Rayamajhi
Summary: This study investigated snow leopard prey preference in the Kangchenjunga Conservation Area of eastern Nepal, finding that snow leopards show a higher preference for domestic livestock over wild prey due to the smaller available biomass of wild prey in the region. Recommendations include improving livestock insurance, enhancing livestock guarding, building predator-proof corrals, engaging locals in snow leopard conservation efforts, and promoting ecotourism.
ECOLOGY AND EVOLUTION
(2021)
Article
Environmental Sciences
Muhammad Jawad Sajid, Syed Abdul Rehman Khan, Ernesto D. R. Santibanez Gonzalez
Summary: Renewable energy consumption is crucial for sustainable development. However, the factors influencing China's decreasing share of renewable energy usage have not been well studied. This research addresses the gap by investigating these factors and identifies combustible renewables and waste as the most critical factor.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Li Qin, Lijiang Liu, Jiangying Tu, Guogen Yang, Sheng Wang, Teagen D. Quilichini, Peng Gao, Hong Wang, Gary Peng, Elison B. Blancaflor, Raju Datla, Daoquan Xiang, Kenneth E. Wilson, Yangdou Wei
Summary: The actin cytoskeleton plays a critical role in regulating cellular activities in plant-microbe interactions and immunity. The assembly and turnover of actin filaments at pathogen interaction sites are regulated by the ARP2/3 complex and W/SRC. Phosphatidylinositol-4,5-bisphosphate accumulation at fungal penetration sites modulates actin patch formation.
Article
Multidisciplinary Sciences
Alisha N. Jones, Andre Mourao, Anna Czarna, Alex Matsuda, Roberto Fino, Krzysztof Pyrc, Michael Sattler, Grzegorz M. Popowicz
Summary: The replication complex (RC) of SARS-CoV-2 has a fast RNA-dependent RNA polymerase activity, resulting in highly variable genomic sequences. This study characterized the RNA template recognition and elongation fidelity of SARS-CoV-2 RdRp and the role of the exonuclease, nsp14, through biochemical experiments. The results highlight the importance of the 2' OH group in RdRp template recognition and elongation, and suggest the potential use of 3' deoxy-terminator nucleotides as antivirals against SARS-CoV-2.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
James Bennett Derr, Katarzyna Rybicka-Jasinska, Eli Misael Espinoza, Maryann Morales, Mimi Karen Billones, John Anthony Clark, Valentine Ivanov Vullev
Summary: Biological structure-function relationships provide important paradigms for charge-transfer science, with implications for solar-energy engineering, organic electronics, and photonics. This publication focuses on the synthesis of molecular electrets with ether substituents, highlighting challenges and methods in their production.
Article
Chemistry, Physical
Luca Craciunescu, Eirik M. Liane, Adam Kirrander, Martin J. Paterson
Summary: In this study, the excited state van der Waals (vdW) potential energy surfaces (PESs) of the NO A(2)Sigma(+) + CO2 X-1 Sigma(+)(g) system were thoroughly investigated using advanced computational methods. The results show that the employed methods are efficient and cost-effective in predicting the depth of vdW wells. Furthermore, the study highlights the influence of multi-reference effects and long-range vdW surfaces on rotational energy transfer.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Computer Science, Artificial Intelligence
Joao Marques-Silva, Alexey Ignatiev
Summary: In recent years, there have been several proposals to use interpretable models in various application domains, including high-risk and safety-critical fields. However, some studies have highlighted the limitations of machine learning model interpretability due to the absence of a clear definition for interpretable models. This study introduces the concept of interpretability as the ability of a model to provide explanations for its predictions based on the feature space. It further explores the limitations of interpretable models in domains where human decision makers require explanations for predictions and minimal information. The study argues that in such domains, the answers to why or why not questions can exhibit arbitrary redundancy, as long as these answers are obtained through human inspection of the interpretable ML model representation.
FRONTIERS IN ARTIFICIAL INTELLIGENCE
(2023)
Article
Multidisciplinary Sciences
Xuan Xie, Xia Sun, Yuheng Wang, Ben Lehner, Xianghua Li
Summary: This article discusses how mutations interact to alter phenotypes and concludes that non-additive interactions (epistasis and dominance) are frequent, context-dependent, and challenging to predict even in the simplest biological systems.
NATURE COMMUNICATIONS
(2023)
Article
Behavioral Sciences
Michael Andrew Ranney, Leela Velautham
Summary: Addressing climate change requires a multi-faceted approach in education and communication to gradually increase acceptance and reduce ignorance and denial. Advances in various climate education realms, including in-school and extra-school learning, social-emotional learning, and techniques for addressing misinformation, are crucial in boosting awareness and concern about global warming.
CURRENT OPINION IN BEHAVIORAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Cuiting Peng, Haixia Zhang, Jun Ren, Han Chen, Ze Du, Tong Zhao, Aiping Mao, Ruofan Xu, Yulin Lu, He Wang, Xinlian Chen, Shanling Liu
Summary: Thalassemia is a common hereditary anemia with significant morbidity and mortality worldwide. Precise diagnosis of thalassemia, especially rare variants, remains challenging. This study utilized long-range PCR and long-molecule sequencing to diagnose common and rare types of thalassemia variants. Compared with traditional methods, the study identified rare clinically significant variants that were misdiagnosed previously. The results validated third-generation sequencing as a promising method for rare thalassemia genetic testing.
SCIENTIFIC REPORTS
(2022)
Article
Engineering, Biomedical
Ming-Chen Sun, Ying-Fang Chen, Di Liu, Xiao-Ling Xu, Yu-Chan You, Wei Lu, Yun-Juan Shi, Ming-Yang Ren, Yi-Bin Fan, Yong-Zhong Du, Xiao-Hua Tao
Summary: The widespread use of mupirocin for treating MRSA infections has led to the emergence of mupirocin-resistant Staphylococcus aureus (MuRSA), posing a serious medical threat. In order to combat MuRSA, researchers have developed a modified mupirocin and silver complex (TPGS/Mup-Ag) to enhance its antibacterial activity. The results showed that TPGS/Mup-Ag can effectively eliminate bacterial infection and accelerate wound healing in both in vitro and in vivo experiments.
MATERIALS TODAY BIO
(2023)
Article
Multidisciplinary Sciences
Xiaoxing Liang, Xujun Chen, Cheng Li, Jun Fan, Zejian Guo
SCIENTIFIC REPORTS
(2017)
Article
Plant Sciences
Qi Luo, Wei-Wei Liu, Ke-Di Pan, You-Liang Peng, Jun Fan
FRONTIERS IN PLANT SCIENCE
(2017)
Article
Plant Sciences
Mohamed Hanchi, Marie-Christine Thibaud, Bertrand Legeret, Keiko Kuwata, Nathalie Pochon, Fred Beisson, Aiqin Cao, Laura Cuyas, Pascale David, Peter Doerner, Ali Ferjani, Fan Lai, Yonghua Li-Beisson, Jerome Mutterer, Michel Philibert, Kashchandra G. Raghothama, Corinne Rivasseau, David Secco, James Whelan, Laurent Nussaume, Helene Javot
Article
Plant Sciences
Mario Valerio Giuffrida, Peter Doerner, Sotirios A. Tsaftaris
Article
Multidisciplinary Sciences
Ya-Li Fang, You-Liang Peng, Jun Fan
SCIENTIFIC REPORTS
(2017)
Article
Plant Sciences
Frank Qasim Machin, Malin Beckers, Xin Tian, Alice Fairnie, Teri Cheng, Wolf-Ruediger Scheible, Peter Doerner
Article
Biotechnology & Applied Microbiology
Jun-Zhou Li, Li-Ying Zhou, You-Liang Peng, Jun Fan
MICROBIAL BIOTECHNOLOGY
(2020)
Review
Plant Sciences
Cristobal Concha, Peter Doerner
JOURNAL OF EXPERIMENTAL BOTANY
(2020)
Editorial Material
Plant Sciences
Peter Doerner
JOURNAL OF EXPERIMENTAL BOTANY
(2020)
Article
Plant Sciences
Thibaut Bontpart, Cristobal Concha, Mario Valerio Giuffrida, Ingrid Robertson, Kassahun Admkie, Tulu Degefu, Nigusie Girma, Kassahun Tesfaye, Teklehaimanot Haileselassie, Asnake Fikre, Masresha Fetene, Sotirios A. Tsaftaris, Peter Doerner
Article
Biochemistry & Molecular Biology
Bao-Zhu Dong, Xiao-Qiong Zhu, Jun Fan, Li-Yun Guo
Summary: This study elucidated the mechanism of wart formation induced by B. dothidea invasion and the crucial roles of the cutinase gene Bdo_10846 in pathogen virulence and inducing plant immunity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Jun-Bin Chen, Shu-Wen Bao, Ya-Li Fang, Lu-Yang Wei, Wang-Sheng Zhu, You-Liang Peng, Jun Fan
Summary: NLPs are a superfamily of proteins toxic to dicot plants, and the NTCD4 protein plays an important role in the toxicity of MoNLP1. NTCD4 protein promotes the oligomerization of NLP, which is a key step in causing plant toxicity.
Article
Plant Sciences
Meng-Meng Chen, Si-Ru Yang, Jian Wang, Ya-Li Fang, You-Liang Peng, Jun Fan
Summary: Oxysterol-binding protein-related proteins (ORPs) play important roles in plant-pathogen interactions, triggering oxidative bursts and promoting plant innate immunity; they are also essential for the growth, development, and virulence of fungal pathogens.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Article
Biochemistry & Molecular Biology
Haijiao Xu, Qingle Chang, Luli Huang, Peiyao Wei, Yulu Song, Zejian Guo, You-Liang Peng, Jun Fan
Summary: Agrobacterium-mediated transient expression (AMTE) has been widely used for high-throughput assays of gene function in diverse plant species. However, its efficiency in monocots is limited. In this study, we optimized AMTE on intact barley plants and demonstrated its efficiency on wheat and rice plants as well. We also incorporated AMTE into the functional analysis of plant disease and identified candidate genes promoting blast disease on barley plants using the AMTE protocol. These findings highlight the potential of the optimized AMTE approach as an effective tool for studying plant-microbe interactions in monocots.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Qing-Le Chang, Hai-Jiao Xu, You-Liang Peng, Jun Fan
PHYTOPATHOLOGY RESEARCH
(2019)