Review
Immunology
Yuji Nozaki
Summary: Biologics targeting inflammation-related molecules have revolutionized the treatment of rheumatoid arthritis and ANCA-associated vasculitis. However, challenges remain in treating vasculitis effectively. New drugs in clinical trials offer promising options for vasculitis treatment.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Plant Sciences
Ana Lopez-Moral, Carlos Agusti-Brisach, Antonio Trapero
Summary: This study evaluated the effects of 32 products on Verticillium wilt of olive, showing wide ranging responses and disease reduction levels among the products tested, suggesting multiple modes of action.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Plant Sciences
Yun Long, Yun Yang, Guangtang Pan, Yaou Shen
Summary: This review summarizes two regenerative pathways in tissue culture, along with the environmental factors influencing plant regeneration. The molecular mechanisms underlying these pathways are also analyzed. This knowledge is crucial for the application of plant micropropagation and genetic modification.
FRONTIERS IN PLANT SCIENCE
(2022)
Review
Plant Sciences
Gourav Sharma, Jacob N. Barney, James H. Westwood, David C. Haak
Summary: Weeds, as a unique group of stress tolerators, have evolved traits that enable them to rapidly adapt to harsh environments. Studying weeds can provide insights into weed management and crop improvement by gaining a deeper understanding of their mechanisms, adaptations, and genetic and physiological bases for stress tolerance.
TRENDS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Siarhei A. Dabravolski, Stanislav V. Isayenkov
Summary: Our study elucidates the evolution of the voltage-independent TPK (two-pore K+-channels) family, represented in some species by one pore, K+-inward rectifier (Kir)-like channels. Through a comprehensive investigation of existing databases and modern bioinformatic tools, we have gained insight into the evolutionary origin of TPK family proteins by conducting a detailed phylogenetic inventory of TPK/KCO3 (KCO: potassium channel, outward rectifying) channels across many taxa.
Review
Plant Sciences
Chunyue Guo, Jun Zhou, Dengwen Li
Summary: IQ67-domain (IQD) proteins are plant-specific calmodulin-binding proteins that play a critical role in plant growth, development, and drought tolerance. Although they have been characterized in several plant species, the precise molecular mechanisms underlying their biological functions remain incompletely understood.
FRONTIERS IN PLANT SCIENCE
(2021)
Editorial Material
Plant Sciences
Ulrike Bauer, Simon Poppinga
Summary: Mechanical ecology is an emerging interdisciplinary field that explores the mechanical aspects of plant ecology, with recent advancements in portable devices allowing for more in-depth biomechanical field studies.
JOURNAL OF EXPERIMENTAL BOTANY
(2022)
Review
Cell & Tissue Engineering
Qingyin Lin, Jiaqi Chen, Lifang Gu, Xingang Dan, Cheng Zhang, Yanzhou Yang
Summary: Mitophagy is a crucial autophagic process that plays a key role in clearing damaged mitochondria and maintaining the health and longevity of stem cells. Decreased mitophagy can impact the regenerative capacity of stem cells, which is essential for preventing tissue aging.
STEM CELL RESEARCH & THERAPY
(2021)
Article
Environmental Sciences
Kalpana Bhatt, Deep Chandra Suyal, Saurabh Kumar, Kuldeep Singh, Priya Goswami
Summary: Rapid industrialization and overutilization of organic pollutants have altered the environment, and the interaction between plants and microbes has the potential for sustainable removal of pollutants and enhancement of crop productivity.
Review
Medicine, Research & Experimental
Qi Fan, He Nan, Zhe Li, Bingtong Li, Fangze Zhang, Liqi Bi
Summary: Mucosal-associated invariant T (MAIT) cells are T cells that reside in mucosal tissues, expressing semi-invariant TCR chains and being restricted by monomorphic MHC class I-related molecules (MR1). They can be activated by microbial-specific metabolites or cytokines. Activated MAIT cells display pro-inflammatory, migratory, and cytolytic properties through the production of chemokines, cytotoxic molecules, and pro-inflammatory cytokines. In autoimmune diseases, MAIT cells contribute to inflammation and disease progression. This review summarizes the biological characteristics, activation mechanism, dynamic migration, and dual functions of MAIT cells, and focuses on their potential applications in the diagnosis and treatment of autoimmune diseases.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Editorial Material
Plant Sciences
Navneet Kaur, Swapna Nayakoti, Natasha Brock, Nigel G. Halford
Summary: Epigenetic modifications, particularly the presence of 5mC oxidation derivatives, have been found to play an important role in regulating gene expression in plants. Kalinka et al. (2023) discovered the presence of 5-hydroxy-methylcytosine (5hmC) and other derivatives in the rye genome, and demonstrated their association with coding regions of DNA, suggesting a potential role in plant genome regulation.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Review
Immunology
Dapeng Cheng, Xiaochen Zhu, Shaochen Yan, Linli Shi, Zhi Liu, Xin Zhou, Xinling Bi
Summary: Inflammatory memory is a form of innate immune memory that is associated with cell epigenetic modification or metabolic transformation. Cells with inflammatory memory function show enhanced or tolerated inflammatory response when re-encountering similar stimuli. Various stem cells, including hematopoietic stem cells and fibroblasts, as well as stem cells from barrier epithelial tissues, can generate and maintain inflammatory memory. Epidermal stem cells, especially hair follicle stem cells, play a crucial role in wound healing, immune-related skin diseases, and skin cancer development. Recent research has shown that hair follicle epidermal stem cells can remember inflammatory responses and exhibit a faster response to subsequent stimuli. This review provides an update on the advances of inflammatory memory and focuses on its mechanisms in epidermal stem cells. Further research on inflammatory memory is eagerly awaited to develop precise strategies for manipulating host responses to infection, injury, and inflammatory skin diseases.
FRONTIERS IN IMMUNOLOGY
(2023)
Editorial Material
Biochemistry & Molecular Biology
W. Scott Armbruster
Summary: This study shows that rapid movements of stamens can enhance male fitness by deterring pollinators after pollen transfer.
Article
Plant Sciences
Yifan Chen, Changjuan Jiang, Shixin Yin, Juhua Zhuang, Yue Zhao, Lingjie Zhang, Xiaolan Jiang, Yajun Liu, Liping Gao, Tao Xia
Summary: In this study, it was discovered that tannase in tea plants is not only a hydrolase, but also an acyltransferase. Through enzyme and metabolic analysis, it was found that overexpression of tannase increased the total contents of simple galloyl glucoses and flavan-3-ol gallates in strawberry, tea, and Chinese bayberry.
Review
Biochemistry & Molecular Biology
Jing Guo, Chang Shan, Jiao Xu, Mei Li, Jiayu Zhao, Wei Cheng
Summary: This review summarizes the expressions and functions of TRP ion channels in stem cells, including cancer stem cells, highlighting their role in sensory functions and regulation of stem cell characteristics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)