期刊
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
卷 17, 期 5, 页码 363-372出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOO.0b013e3283303513
关键词
apoptosis; direct transdifferentiation; endocochlear potential; gene therapy; stem cells
Purpose of review In evaluating strategies to preserve or regenerate the cochlea, understanding the process of labyrinthine injury on a cellular and molecular level is crucial. Examination of inner ear injury reveals mechanism-specific types of damage, often at specific areas within the cochlea. Site-specific interventions can then be considered. Recent findings The review will briefly summarize the historical perspective of advancements in hearing science through 2006. Areas of research covered include hair cell protection, hair cell regeneration, spiral ganglion cell regeneration, and stria vascularis metabolic regulation. Summary The review will briefly summarize the early development of a few such site-specific interventions for inner ear functional rehabilitation, for work done prior to 2006. The outstanding reviews of cutting edge research from this year's and last year's Hearing Science section of Current Opinion in Otolaryngology - Head and Neck Surgery can then be understood and appreciated in a more informed manner.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据