期刊
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY
卷 16, 期 3, 页码 205-210出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MOO.0b013e3282febd3a
关键词
speech disorders and Parkinson disease; swallowing disorders and Parkinson disease; voice disorders and Parkinson disease
资金
- National Institutes of Health -National Institute of Deafness [R01 DC 1150]
Purpose of review To review recent research and clinical studies pertaining to the nature, diagnosis, and treatment of speech and swallowing disorders in Parkinson disease. Recent findings Although some studies indicate improvement in voice and speech with dopamine therapy and deep brain stimulation of the subthalamic nucleus, others show minimal or adverse effects. Repetitive transcranial magnetic stimulation of the mouth motor cortex and injection of collagen in the vocal folds have preliminary data supporting improvement in phonation in people with Parkinson disease. Treatments focusing on vocal loudness, specifically LSVT LOUD (Lee Silverman Voice Treatment), have been effective for the treatment of speech disorders in Parkinson disease. Changes in brain activity due to LSVT LOUD provide preliminary evidence for neural plasticity. Computer-based technology makes the Lee Silverman Voice Treatment available to a large number of users. A rat model for studying neuropharmacologic effects on vocalization in Parkinson disease has been developed. New diagnostic methods of speech and swallowing are also available as the result of recent studies. Summary Speech rehabilitation with the LSVT LOUD is highly efficacious and scientifically tested. There is a need for more studies to improve understanding, diagnosis, prevention, and treatment of speech and swallowing disorders in Parkinson disease. Keywords
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