期刊
CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
卷 26, 期 3, 页码 145-150出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GCO.0000000000000065
关键词
endometriosis; fertility; in-vitro fertilization; polycystic ovary syndrome; vitamin D
Purpose of reviewApart from the well known effects of vitamin D on maintaining calcium homeostasis and promoting bone mineralization, there is some evidence suggesting that vitamin D also modulates human reproductive processes. We will review the most interesting and relevant studies on vitamin D and female fertility published over the past year.Recent findingsIn the past year, several observational studies reported a better in-vitro fertilization outcome in women with sufficient vitamin D levels (30ng/ml), which was mainly attributed to vitamin D effects on the endometrium. One randomized controlled trial found an increased endometrial thickness in women with polycystic ovary syndrome (PCOS) receiving vitamin D during intrauterine insemination cycles. Further, vitamin D supplementation had a beneficial effect on serum lipids in PCOS women. Vitamin D treatment improved endometriosis in a rat model and increased vitamin D intake was related to a decreased risk of incident endometriosis. Vitamin D was also favorably associated with primary dysmenorrhea, uterine leiomyoma, and ovarian reserve in late reproductive aged women.SummaryIn women undergoing in-vitro fertilization, a sufficient vitamin D level (30ng/ml) should be obtained. Vitamin D supplementation might improve metabolic parameters in women with PCOS. A high vitamin D intake might be protective against endometriosis.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据