期刊
CURRENT OPINION IN NEUROBIOLOGY
卷 22, 期 4, 页码 704-708出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2012.03.007
关键词
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资金
- NIMH NIH HHS [R01 MH090188] Funding Source: Medline
Many neural circuits process information in multiple distinct modes. For example, the hippocannpus is involved in memory encoding, retrieval, and consolidation processes. These different mnemonic computations require processing of differing balances of current sensory input and previously stored associations. Here we explore patterns of activity in hippocampal output area CA1 associated with different information processing states. We discuss the evidence linking these patterns to specific inputs to CA1 and describe behavioral factors that are related to the balance of synaptic drive. We suggest that understanding the factors that influence information flow in the hippocampal circuit could provide important new insights into how neural circuits are reconfigured on the fly to perform different functions at different times.
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