Article
Chemistry, Multidisciplinary
Xin Li, Dehan Luo, Yu Cheng, Kin-Yeung Wong, Kevin Hung
Summary: This study discusses the selection mechanism of odor perception descriptors and proposes the task of reducing the number of such descriptors. Experimental results show that dozens of odor perception descriptors are redundant, and reducing the size of the odor vocabulary can simplify odor sensory assessment.
APPLIED SCIENCES-BASEL
(2021)
Article
Multidisciplinary Sciences
Naoto Sato, Mana Miyamoto, Risa Santa, Ayaka Sasaki, Kenichi Shibuya
Summary: In this study, we investigated the cross-modal effect between odors and colors, both under recognizable and unrecognizable conditions. By using different concentrations of flavors from strawberries and tomatoes, we compared whether similar cross-modal effects can be obtained. The results showed that each odor, except for the subliminal tomato condition, was significantly associated with at least one color. This study suggests that the flavor of tomatoes produced a cross-modal effect in recognizable conditions, while the flavor of strawberries produced a cross-modal effect even in unrecognizable conditions.
Article
Biochemistry & Molecular Biology
Pankaj Tyagi, Anju Sharma, Rahul Semwal, Uma Shanker Tiwary, Pritish Kumar Varadwaj
Summary: This study developed an XGBoost odor prediction model using machine learning technology, which was able to classify smells of odorant molecules. The results showed that the model could predict all seven basic smells with high precision (>99%) and high sensitivity (>99%), and outperformed other models in predicting common odor descriptors.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Neurosciences
Vittoria Avaro, Thomas Hummel, Federico Calegari
Summary: Olfaction plays a crucial role in the ability of animals to perceive chemicals, and adult neurogenesis has a unique impact on olfactory function. However, the role of newborn neurons in olfactory sensitivity, discrimination, and memory remains controversial.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Rui Xu, Xiaojing Cong, Qian Zheng, Lun Xu, Mengjue J. Ni, Claire A. March, Hiroaki Matsunami, Jerome Golebiowski, Minghong Ma, Yiqun Yu
Summary: This study investigated the heterologous expression and functional assays of over 80 OR variants and chimeras. The results showed that the transmembrane domain 4 (TM4) and its interactions with neighboring residues play important roles in OR functional expression. Modifications in TM4 can rescue ORs that fail to reach the cell membrane. Additionally, modifications in MOR256-3 (Olfr124) were found to alter OR responses to odorants.
Article
Evolutionary Biology
Michael R. Vella, Fred Gould, Alun L. Lloyd
Summary: Research has shown that both single- and two-construct arrangements for genetic approaches to combat insect pests have their advantages, with the former resulting in faster initial population suppression and the latter eventually causing more powerful suppression and local elimination with a smaller release size.
EVOLUTIONARY APPLICATIONS
(2021)
Review
Cell Biology
Andrew J. Modzelewski, Johnny Gan Chong, Ting Wang, Lin He
Summary: This review discusses how sequences introduced by transposon activities contribute to genome innovation and document the evolutionary path of each species.
NATURE CELL BIOLOGY
(2022)
Article
Construction & Building Technology
Juan Wang, Yinping Zhang, Baizhan Li, Zhuohui Zhao, Chen Huang, Xin Zhang, Qihong Deng, Chan Lu, Hua Qian, Xu Yang, Yuexia Sun, Dan Norba
Summary: A questionnaire survey was conducted in eight Chinese cities, involving 40,279 adults with a response rate of 75%. The survey focused on demographic information, allergic rhinitis, asthma, perceived odors, and home environment. The results showed that mold and dampness in dwellings were associated with adult allergic rhinitis, asthma, and odors. Different odors were related to allergic rhinitis and asthma. Odor perception partly mediated the effects of mold and dampness on allergic rhinitis and asthma, but most of the effects were direct.
BUILDING AND ENVIRONMENT
(2023)
Review
Agriculture, Dairy & Animal Science
Amanda J. Barabas, Stephanie R. Dijak, Jane F. Yatcilla, Danielle N. Walker, Brianna N. Gaskill
Summary: Many species use olfaction as a primary form of communication, and odor signals could be a useful tool to improve captive animal welfare. However, existing literature on the effects of mammalian odors on non-reproductive social behavior is limited in quality, with a focus on urine treatments in sexually mature male rodents and their effects on aggression.
APPLIED ANIMAL BEHAVIOUR SCIENCE
(2021)
Article
Engineering, Environmental
Mingmin Zhong, Zhixiong Lao, Jianrong Tan, Guangzhou Yu, Yan Liu, Yong Liang
Summary: This study proposes a method combining PT-GC/MS and GC for the detection of T&O compounds in unknown odorous water. The results show that the method can simultaneously detect multiple T&O compounds and has the potential to be widely used in the detection of unknown odors in smelling water.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Editorial Material
Microbiology
Kaveh Ashrafi
Summary: A recent study in Cell Host & Microbe revealed that signals from Escherichia coli, as well as the host's neural and innate immunity pathways, promote the digestion of Staphylococcus saprophyticus by Caenorhabditis elegans.
CELL HOST & MICROBE
(2022)
Review
Cell Biology
Smija M. Kurian, Rafaella G. Naressi, Diogo Manoel, Ann-Sophie Barwich, Bettina Malnic, Luis R. Saraiva
Summary: Odor detection starts with the activation of odorant receptors in mature olfactory sensory neurons, and different odorants activate unique receptors, providing an explanation for perceiving different odors. Recent studies have found that antagonist interactions play an important role in the formation of combinatorial receptor code.
CELL AND TISSUE RESEARCH
(2021)
Article
Neurosciences
Shiloh L. Echevarria-Cooper, Guangyu Zhou, Christina Zelano, Franco Pestilli, Todd B. Parrish, Thorsten Kahnt
Summary: The human sense of smell plays a crucial role in appetite, detecting threats, social interactions, and memory processing. In this study, we used a novel dMRI method to investigate the connectivity of the human olfactory tracts. Our results revealed an association between the structural integrity of the olfactory tracts and olfactory perceptual function.
JOURNAL OF NEUROSCIENCE
(2022)
Editorial Material
Multidisciplinary Sciences
Karen H. Miga
Summary: Since the publication of the human genome in 2001, advancements in sequencing technology have filled in many of the gaps in the original sequence, leading to a deeper knowledge of genome regulation, structure, and function.
Article
Multidisciplinary Sciences
Alexa Sadier, Neal Anthwal, Andrew L. Krause, Renaud Dessalles, Michael Lake, Laurent A. Bentolila, Robert Haase, Natalie A. Nieves, Sharlene E. Santana, Karen E. Sears
Summary: Tooth classes are an important factor in the evolutionary success of mammals, but the mechanisms behind their diversification are not well understood. Through the study of noctilionoid bats, researchers have shown how the tooth developmental program evolved during adaptation to different diets. They found that tooth classes develop through independent developmental cascades that deviate from classical models, and that the diversification of tooth number and size is driven by jaw growth rate modulation. Mathematical models also supported the hypothesis that growth plays a key role in the evolution of tooth number and size. This study sheds light on the diversification of tooth classes and other repeated structures during adaptive radiations.
NATURE COMMUNICATIONS
(2023)
Article
Biochemical Research Methods
Andrew S. Warren, Cristina Aurrecoechea, Brian Brunk, Prerak Desai, Scott Emrich, Gloria I. Giraldo-Calderon, Omar Harb, Deborah Hix, Daniel Lawson, Dustin Machi, Chunhong Mao, Michael McClelland, Eric Nordberg, Maulik Shukla, Leslie B. Vosshall, Alice R. Wattam, Rebecca Will, Hyun Seung Yoo, Bruno Sobral
Editorial Material
Multidisciplinary Sciences
Leslie B. Vosshall
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2015)
Article
Biotechnology & Applied Microbiology
Benjamin J. Matthews, Carolyn S. McBride, Matthew DeGennaro, Orion Despo, Leslie B. Vosshall
Article
Neurosciences
Andreas Keller, Leslie B. Vosshall
Article
Biochemistry & Molecular Biology
Nilay Yapici, Raphael Cohn, Christian Schusterreiter, Vanessa Ruta, Leslie B. Vosshall
Article
Multidisciplinary Sciences
Julien W. Hsieh, Andreas Keller, Michele Wong, Rong-San Jiang, Leslie B. Vosshall
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2017)
Article
Multidisciplinary Sciences
Andreas Keller, Richard C. Gerkin, Yuanfang Guan, Amit Dhurandhar, Gabor Turu, Bence Szalai, Joel D. Mainland, Yusuke Ihara, Chung Wen Yu, Russ Wolfinger, Celine Vens, Leander Schietgat, Kurt De Grave, Raquel Norel, Gustavo Stolovitzky, Guillermo A. Cecchi, Leslie B. Vosshall, Pablo Meyer
Article
Multidisciplinary Sciences
C. Trimmer, A. Keller, N. R. Murphy, L. L. Snyder, J. R. Willer, M. H. Nagai, N. Katsanis, L. B. Vosshall, H. Matsunami, J. D. Mainland
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2019)
Article
Biology
Benjamin J. Matthews, Meg A. Younger, Leslie B. Vosshall
Review
Biology
Benjamin J. Matthews, Leslie B. Vosshall
JOURNAL OF EXPERIMENTAL BIOLOGY
(2020)
Editorial Material
Biology
Michael H. Dickinson, Leslie B. Vosshall, Julian A. T. Dow
JOURNAL OF EXPERIMENTAL BIOLOGY
(2020)
Article
Biology
Nipun S. Basrur, Maria Elena De Obaldia, Takeshi Morita, Margaret Herre, Ricarda K. von Heynitz, Yael N. Tsitohay, Leslie B. Vosshall
Article
Biology
Trevor R. Sorrells, Anjali Pandey, Adriana Rosas-Villegas, Leslie B. Vosshall
Summary: Mosquitoes can continuously track and feed on blood by utilizing a persistent behavioral state triggered by detection of human cues. This state is observed only in female mosquitoes searching for blood and can last for more than ten minutes.
Article
Biochemistry & Molecular Biology
Maria Elena De Obaldia, Takesh Morita, Laura C. Dedmon, Daniel J. Boehmler, Caroline S. Jiang, Emely Zeledon, Justin R. Cross, Leslie B. Vosshall
Summary: Some individuals produce more carboxylic acids in their skin em- anations, which make them more attractive to mosquitoes. Mutant mosquitoes lacking certain chemosensory co-receptors show impaired attraction to human scent, but can still differentiate between highly and weakly attractive individuals.
Article
Biology
Roman A. Corfas, Leslie B. Vosshall
