Article
Geriatrics & Gerontology
Soheila Rezaei, Mohammad Peikanpour, Leila Zarei, Ghader Mohammadnezhad, Jamshid Salamzadeh
Summary: According to the study, older adult patients with chronic diseases are influenced by socio-economic factors, health system-related factors, healthcare provider-related factors, medication-related factors, disease-related factors, and patient-related factors, which affect their medication adherence.
Article
Pharmacology & Pharmacy
Majed A. Algarni, Meznah S. Althobiti, Sarah A. Alghamdi, Huriyyah A. Alotaibi, Ohoud S. Almalki, Adnan Alharbi, Mohammad S. Alzahrani
Summary: Medication adherence is a crucial factor in managing diseases. Our study found that chronic patients in the Makkah region are more likely to be non-adherent to their medications compared to patients in other regions. Additionally, lower monthly incomes and out-of-pocket medication expenses were significant predictors of medication non-adherence.
Review
Urology & Nephrology
Daniel V. O'Hara, Tae Won Yi, Vincent W. Lee, Meg Jardine, Jessica Dawson
Summary: Non-adherence to medications is a critical challenge in the management of people with chronic kidney disease. This review examines the role of emerging digital health technologies in addressing adherence issues and provides practical strategies for clinicians to support medication adherence.
Review
Health Care Sciences & Services
Mieke H. J. Schulte, Jiska J. Aardoom, Lisa Loheide-Niesmann, Leonie L. L. Verstraete, Hans C. Ossebaard, Heleen Riper
Summary: This review investigates the effects of eHealth interventions on medication adherence in patients with COPD or asthma. The results show mixed effects, possibly due to the type, context, and intensity of the interventions, as well as differences in the operationalization and measurement of adherence outcomes. Further research is needed to fully understand the potential of eHealth in optimizing treatment adherence for COPD and asthma.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Health Care Sciences & Services
Ping-Hsun Wu, Ming-Yen Lin, Teng-Hui Huang, Tien-Ching Lee, Sung-Yen Lin, Chung-Hwan Chen, Mei-Chuan Kuo, Yi-Wen Chiu, Jer-Ming Chang, Shang-Jyh Hwang
Summary: This study aimed to investigate the safety, treatment adherence, renal function effect, and mortality of denosumab in CKD patients. The results showed that high adherence users had better renal function and no decline in renal function. The all-cause mortality rate was lower in high adherence users compared to low adherence users in both the overall cohort and CKD subcohort.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Farida Islahudin, Fei Yee Lee, Tengku Nur Izzati Tengku Abd Kadir, Muhammad Zulhilmi Abdullah, Mohd Makmor-Bakry
Summary: The study aimed to develop an adherence prediction model for CKD patients by collecting patient data from 10 tertiary hospitals in Malaysia. Results showed that the model accurately identified high-risk non-adherent patients based on patient characteristics, medication adherence, and medication knowledge.
RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY
(2021)
Article
Biology
Daopeng Dai, Zhengbin Zhu, Hui Han, Tian Xu, Shuo Feng, Wenli Zhang, Fenghua Ding, Ruiyan Zhang, Jinzhou Zhu
Summary: Chronic kidney disease (CKD) is associated with increased sulfation status, which contributes to monocyte/macrophage activation and may be involved in CKD-related atherosclerosis. Inhibition of sulfation may suppress CKD-related atherosclerosis and deserves further study.
Article
Pediatrics
Rushelle L. Byfield, Rui Xiao, Daichi Shimbo, Ian M. Kronish, Susan L. Furth, Sandra Amaral, Jordana B. Cohen
Summary: Nonadherence to antihypertensive medication is common in children with CKD and does not appear to be associated with kidney function or cardiac structure over time.
PEDIATRIC NEPHROLOGY
(2023)
Article
Nursing
Goncagul Aldan, Aylin Helvaci, Leyla Ozdemir, Seher Satar, Pinar Ergun
Summary: This study aimed to investigate the effects of various factors on medication adherence in patients with COPD. The results showed that medication adherence was mostly affected by patient-, treatment- and condition-related factors. Healthcare professionals should focus on training and counselling programs to improve medication adherence, especially for newly diagnosed patients requiring multiple drugs, or with comorbid diseases or low self-efficacy.
JOURNAL OF CLINICAL NURSING
(2022)
Review
Pharmacology & Pharmacy
Piotr Merks, Jameason Cameron, Krzysztof Bilmin, Damian Swieczkowski, Tomira Chmielewska-Ignatowicz, Tomasz Harezlak, Katarzyna Bialoszewska, Katarina Fehir Sola, Milosz J. Jaguszewski, Regis Vaillancourt
Summary: Pharmaceutical care requires a patient-centered approach to ensure medication adherence, considering factors such as geography, social economic status, age, and low literacy. Various medication counselling and education approaches, including the use of pictograms, have been explored to improve medication adherence and health outcomes.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Pharmacology & Pharmacy
Pia M. Schumacher, Nina Griese-Mammen, Juliana Schneider, Ulrich Laufs, Martin Schulz
Summary: The study analyzed the changes in medication treatment plans for chronic heart failure patients through an interdisciplinary physician-pharmacist medication review, finding that most patients experienced changes in their medication plans, with the addition of previously undocumented drugs being the most common alteration.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Nursing
Yu Chen, Jing Gao, Minmin Lu
Summary: This systematic review synthesized 50 studies on medication adherence trajectories among patients with chronic diseases and identified influencing factors. The medication adherence trajectories were categorized into six types: adherence, non-adherence, decreasing adherence, increasing adherence, fluctuating adherence, and moderate adherence. Various patient-related, healthcare team and system-related, socioeconomic, condition-related, and therapy-related factors were found to influence medication adherence trajectories, with marital status and prior medication adherence behavior having moderate evidence of an effect. Healthcare providers should be aware of these diverse trajectories and take appropriate measures to improve medication adherence patterns.
JOURNAL OF ADVANCED NURSING
(2023)
Article
Medicine, General & Internal
Gye-Gyoung Kim, Sung-Hee Yoo, Man-Seok Park, Hyun-Young Park, Jae-Kwan Cha
Summary: This study aimed to identify factors influencing medication beliefs in stroke survivors. The results showed that type D personality, state anxiety, and knowledge about medication are major mediating factors for improving medication beliefs. These results may help healthcare professionals develop strategies to enhance medication adherence by improving patients' medication beliefs.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cell Biology
Shuangshuang Fu, Xiaoru Hu, Zhengwei Ma, Qingqing Wei, Xiaohong Xiang, Siyao Li, Lu Wen, Yumei Liang, Zheng Dong
Summary: The protein p53 in proximal tubular cells plays an important role in the development of chronic kidney problems following cisplatin chemotherapy.
Review
Urology & Nephrology
Wubshet H. Tesfaye, Daniel Erku, Alemayehu Mekonnen, Yonas Getaye Tefera, Ronald Castelino, Kamal Sud, Jackson Thomas, Kehinde Obamiro
Summary: The review summarized the prevalence, determinants, and outcomes of medication non-adherence in adults with CKD. Modifiable determinants of non-adherence mainly included lack of knowledge on CKD, comorbidities, and medications, as well as polypharmacy and medication side effects.
JOURNAL OF NEPHROLOGY
(2021)
