Article
Engineering, Environmental
Yinkun Sun, Dongwei Lu, Hui Zhang, Guanjin Liu, Yichao Hu, Haijiao Xie, Jun Ma
Summary: Oxygen vacancies in metal oxide electrocatalytic membranes have a dual role in generating and transforming ROS, acting as promoters at low concentrations but as inhibitors at high concentrations.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Swati Sachdev, Shamim Akhtar Ansari, Mohammad Israil Ansari, Masayuki Fujita, Mirza Hasanuzzaman
Summary: Climate change has devastating effects on plants, leading to the production of reactive oxygen species (ROS) as byproducts of oxygen consumption. While excessive ROS can disrupt cellular homeostasis, moderate levels can activate growth and stress responses in plants, though the exact mechanisms are not fully understood. Advancements in modern techniques like molecular priming and crop modeling offer potential solutions for managing ROS levels in plants under stress.
Article
Biochemistry & Molecular Biology
Chih-Hsing Hung, Yi-Ching Lin, Yi-Giien Tsai, Yu-Chih Lin, Chia-Hong Kuo, Mei-Lan Tsai, Chao-Hung Kuo, Wei-Ting Liao
Summary: Acrylamide promoted mitochondria-specific ROS generation, increased gene expression of mitochondrial respiratory chain complex II SDHA, induced histone modifications and upregulated PINK1 expression, leading to a macrophage M2 polarization shift in THP-1 cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Geriatrics & Gerontology
Yasunori Fujita, Masumi Iketani, Masafumi Ito, Ikuroh Ohsawa
Summary: Mitochondrial dysfunction and excessive generation of mitochondrial ROS do not predominantly occur in the transition phase and may not play a role in the development of replicative senescence in normal diploid TIG-1 fibroblasts.
EXPERIMENTAL GERONTOLOGY
(2022)
Review
Chemistry, Analytical
Wanchao Yu, Lixia Zhao
Summary: ROS, as important oxidizing species in ecosystems, play various roles and monitoring their concentration is crucial for the environment. The chemiluminescence method has attracted attention for ROS detection due to its high sensitivity and simplicity, showing advances in recent years.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Yoshitaka Kimura, Daisuke Tsukui, Hajime Kono
Summary: Hyperuricemia is associated with numerous diseases such as gout, hypertension, chronic kidney diseases, and cardiovascular diseases. Research has shown that intracellular uric acid production can lead to the generation of reactive oxygen species, which regulate intracellular signaling pathways and may contribute to the development of atherosclerosis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Marco Antonio Lacerda-Abreu, Jose Roberto Meyer-Fernandes
Summary: This review explores the impact of Pi-induced ROS production on physiological processes and disease development, highlighting potential pharmacological targets for conditions such as cardiovascular disease and muscle atrophy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biotechnology & Applied Microbiology
Danling Cheng, Xiaoying Wang, Xiaojun Zhou, Jingchao Li
Summary: Immunotherapy is a promising strategy for cancer treatment, but it faces challenges of low immune responses and immune-related adverse events. Sonodynamic therapy combined with immunotherapy can enhance antitumor immunity, and research on nanosonosensitizers for ROS generation is ongoing.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Hichem Maslah, Charles Skarbek, Catherine Gourson, Marie-Aude Plamont, Stephanie Pethe, Ludovic Jullien, Thomas Le Saux, Raphael Labruere
Summary: A new platform capable of generating cytotoxic agents through intramolecular cyclization has been reported, showing rapid and effective action against cancer cells. This innovative method offers potential for prodrug development in anticancer therapy.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Nanoscience & Nanotechnology
Pin Lyu, Jian Zhu, Chongchong Han, Lei Qiang, Linlin Zhang, Bingbao Mei, Jiehong He, Xiaoyan Liu, Zhenfeng Bian, Hexing Li
Summary: The novel method introduces a way to activate O-2 spontaneously through interfacial oxygen vacancies on carbon-coated TiO2-x, generating reactive oxygen species with versatile applications. The reactive oxygen species exhibit excellent performance in oxidation reactions and inhibition of MCF-7 cancer cells, providing new insight into the effective utilization of O-2 via oxygen vacancies on metal oxides.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Environmental
Rui Liu, Mu-cheng Xu, Jin-yan Yang
Summary: This study investigated the degradation and mechanism of heterogeneous V2O3-activated sodium percarbonate (SPC) process in the presence of oxalic acid (OA). The results showed that SMX degradation strongly depended on SPC dosage and had a wide adaptability to ambient pH in the V2O3/SPC/OA system. Mechanistic experiments revealed the crucial role of (OH)-O-center dot in SMX degradation, and the introduction of OA facilitated the removal process. The presence of certain substances inhibited the decontamination of SMX to varying degrees.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Patryk Szymaszek, Patrycja Sroda, Malgorzata Tyszka-Czochara, Anna Chachaj-Brekiesz, Tomasz Swiergosz, Joanna Ortyl
Summary: Here we report the synthesis of a novel fluorescent probe P182 for quantitative measurement of H2O2. This fluorometric probe displays a fluorescence turn-on response in the presence of H2O2. It offers good performances in terms of sensitivity and response time, and shows non-toxic activity for in vivo studies. This study provides research on molecular fluorescence probe for the detection of H2O2.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Environmental
Jiaming Liu, Zhangwei Yao, Genping Qiu, Yinhua Wan, Weijie Song, Huifeng Zeng, Feifei Yang, Da Zhao, Wenjing Yuan, Peihai Ju, Ruixi Lin, Hengcheng Zhou, Lili Shi, Kang Hu
Summary: Defected porous carbon is developed to sustainably release ROS for the effective degradation of antibiotics, achieving a removal rate of 98% for common antibiotics.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Analytical
Hao Yu, Binjie Chen, Huiming Huang, Zhentao He, Jiangman Sun, Guan Wang, Xinggui Gu, Ben Zhong Tang
Summary: Photodynamic therapy is a non-invasive approach for tumor elimination that is gaining increasing attention. The development of aggregation-induced emission (AIE) active photosensitizers has opened up new possibilities for overcoming the limitations of traditional photodynamic therapy.
Article
Biochemistry & Molecular Biology
Ausra Mongirdiene, Laurynas Skrodenis, Leila Varoneckaite, Gerda Mierkyte, Justinas Gerulis
Summary: This article summarizes the importance of ROS in HFrEF and HFpEF, and discusses treatment strategies including neuroendocrine inhibition and ROS-induced metabolic pathways, providing new insights for HF treatment.