Recent advances in understanding the STSL locus and ABCG5/ABCG8 biology

Phytosterol Feeding Causes Toxicity in ABCG5/G8 Knockout Mice

(2013) Allison L. McDaniel et al.   AMERICAN JOURNAL OF PATHOLOGY

Acceleration of Biliary Cholesterol Secretion Restores Glycemic Control and Alleviates Hypertriglyceridemia in Obese db / db Mice

(2013) Kai Su et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia

(2013) T. Kanaji et al.   BLOOD

Cooperative transcriptional activation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 genes by nuclear receptors including Liver-X-Receptor

(2013) Su Sun Back et al.   BMB Reports

Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease

(2013) Olga Renner et al.   BMC GASTROENTEROLOGY

Phytosterols Promote Liver Injury and Kupffer Cell Activation in Parenteral Nutrition-Associated Liver Disease

(2013) K. C. El Kasmi et al.   Science Translational Medicine

The ABCG8 G574R Variant, Serum Plant Sterol Levels, and Cardiovascular Disease Risk in the Old Order Amish

(2012) Richard B. Horenstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at theABCG5/8lithogenic locus

(2012) Oliver von Kampen et al.   HEPATOLOGY

The ABCG5 ABCG8 Sterol Transporter Opposes the Development of Fatty Liver Disease and Loss of Glycemic Control Independently of Phytosterol Accumulation

(2012) Kai Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice

(2012) Curzio Solca et al.   JOURNAL OF LIPID RESEARCH

Dietary intake of plant sterols stably increases plant sterol levels in the murine brain

(2012) Tim Vanmierlo et al.   JOURNAL OF LIPID RESEARCH

Inflammatory Dilated Cardiomyopathy in Abcg5-deficient Mice

(2012) Dennis W. Wilson et al.   TOXICOLOGIC PATHOLOGY

The plant sterol brassicasterol as additional CSF biomarker in Alzheimer’s disease

(2011) T. Vanmierlo et al.   ACTA PSYCHIATRICA SCANDINAVICA

ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways

(2011) Jesús Méndez-González et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury

(2011) Karim C. El Kasmi et al.   HEPATOLOGY

Plant Sterols Increased IL-6 and TNF-α Secretion from Macrophages, but to a Lesser Extent than Cholesterol

(2011) Makoto Kurano et al.   Journal of Atherosclerosis and Thrombosis

Cerebral Accumulation of Dietary Derivable Plant Sterols does not Interfere with Memory and Anxiety Related Behavior in Abcg5−/− Mice

(2011) Tim Vanmierlo et al.   PLANT FOODS FOR HUMAN NUTRITION

Genetic variations at ABCG5/G8 genes modulate plasma lipids concentrations in patients with familial hypercholesterolemia

(2010) A. Garcia-Rios et al.   ATHEROSCLEROSIS

Genome-wide association analysis of total cholesterol and high-density lipoprotein cholesterol levels using the Framingham Heart Study data

(2010) Li Ma et al.   BMC Medical Genetics

Competitive solubilization of cholesterol and six species of sterol/stanol in bile salt micelles

(2010) Keisuke Matsuoka et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease

(2010) Daniel Teupser et al.   Circulation-Cardiovascular Genetics

Sterol transporter adenosine triphosphate-binding cassette transporter G8, gallstones, and biliary cancer in 62,000 individuals from the general population

(2010) Stefan Stender et al.   HEPATOLOGY

ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis

(2010) Lily Jakulj et al.   JOURNAL OF LIPID RESEARCH

The mouse mutation "thrombocytopenia and cardiomyopathy" (trac) disrupts Abcg5: a spontaneous single gene model for human hereditary phytosterolemia/sitosterolemia

(2009) T. H. Chase et al.   BLOOD

Single nucleotide polymorphism in theABCG8transporter gene is associated with gallbladder cancer susceptibility

(2009) Anvesha Srivastava et al.   LIVER INTERNATIONAL

Significant association ofABCG5604Q andABCG8D19H polymorphisms with gallstone disease

(2008) K.‐K. Kuo et al.   BRITISH JOURNAL OF SURGERY

Single nucleotide polymorphisms in ABCG5 and ABCG8 genes in Chilean subjects with polygenic hypercholesterolemia and controls

(2008) José M. Caamaño et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Genetic Variation in ABC G5/G8 and NPC1L1 Impact Cholesterol Response to Plant Sterols in Hypercholesterolemic Men

(2008) Hai L. Zhao et al.   LIPIDS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS