期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 20, 期 4, 页码 428-432出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2010.04.006
关键词
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资金
- the European Research Council
- Agencia de Gestio d'Ajuts Universitaris i de Recerca de Catalunya [2009_SGR_305]
- Ministerio de Ciencia c Innovacion of Spain [SAF2009_09199]
The collective migration of cells is essential for organogenesis. It requires the establishment of spatial information within the cellular group and a mechanism that controls the onset of cell movement and migratory arrest. In this review I will use two examples of collective cell migration, from Drosophila and the zebrafish, to discuss how genetic analyses have helped to unravel some basic aspects of collective cell migration. Following, I will suggest some general experimental approaches to further advance our understanding of the mechanisms that control the migration of cellular collectives.
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