期刊
CURRENT OPINION IN GENETICS & DEVELOPMENT
卷 19, 期 1, 页码 12-17出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.gde.2008.11.011
关键词
-
资金
- National Cancer Institute
Research on PI 3-kinase (PI3K) is undergoing significant shifts in emphasis. Questions that have been dormant for some time are coming to the forefront, such as the relationship of PTEN to PI3K and the role of AKT in PI3K-driven oncogenesis. Two non-alpha isoforms of Class I PI3K are now established as important determinants in cancer: p110 beta and p110 delta. The oncogenic activities of p110 beta include a non-catalytic function, a finding that will have immediate consequences for drug development.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据