Article
Physiology
Pierre Tawfik, Muhammad K. Hayat Syed, Firas S. Elmufdi, Michael D. Evans, David J. Dries, John J. Marini
Summary: This study compared four different methods for measuring compliance and driving pressure and found that using plateau pressure for static measurements may underestimate the maximum pressure experienced by compromised lung units during dynamic inflation. Utilizing the pressure at zero flow or the inspiratory slope as dynamic measurements may provide a more accurate estimate of the maximum alveolar pressure.
FRONTIERS IN PHYSIOLOGY
(2022)
Review
Chemistry, Multidisciplinary
Wenyan Xie, Xi Wei, Heemin Kang, Hong Jiang, Zhiqin Chu, Yuan Lin, Yong Hou, Qiang Wei
Summary: This review provides an introductory overview of key players in mechanobiology and discusses the state-of-the-art manipulation techniques and novel materials in designing static and dynamic ECM-mimicking biomaterials. It also compares the effects of different static and dynamic mechanical cues on cellular mechanosensing and functions. This review is expected to benefit the development of engineering biomechanical systems to regulate cell functions.
Article
Chemistry, Physical
Dibyajyoti Mohanta
Summary: In this study, we investigated the melting process of dsDNA under varying confinement and found structural transitions and the emergence of local denatured zones. By using enumeration and Fokker-Planck formalism, we determined the survival time of single bubbles and the effect of DNA sequences on the melting process.
Article
Mathematics, Applied
Gianni Dal Maso, Francesco Sapio
Summary: The study focuses on the behavior of solutions to a viscoelastic model with long memory as the rate of change of data approaches zero, and it is proven that a rescaled version of the solutions converges to the solution of the corresponding stationary problem.
MILAN JOURNAL OF MATHEMATICS
(2021)
Article
Automation & Control Systems
Yeqing Yuan, Weichao Sun
Summary: In this article, we propose an integrated calibration and identification method that can simultaneously identify kinematic and dynamic parameters. This method only requires a series of static experiments, which can greatly simplify the experimental operation and improve the accuracy of identification. We develop a novel calibration model based on axis configuration space and adjoint error model considering joint compliance with only position measurements, and include both joint compliance and joint zero-offset errors in the proposed model. Identifiability analysis shows which joint compliance can be identified and the relationships between the identifiability of joint compliance and the number of measurement points. We also derive a recursive algorithm considering physical consistency to obtain the derivatives of estimated inertial matrix and gravity vector with respect to joint twists. By solving the coupling between kinematic and dynamic model, the optimal kinematic and dynamic parameters can be derived using a gradient-based optimizer. Comparative study with experiments is reported to demonstrate the effectiveness of our algorithm.
IEEE-ASME TRANSACTIONS ON MECHATRONICS
(2023)
Article
Mechanics
Alessandro Cabboi, Othman Harrass, Sergio Sanchez Gomez, Mladena Lukovi
Summary: The study characterizes delamination and assesses interface failure mechanism of hybrid concrete beam using static and dynamic tests, involving SHCC beams with different preparation and curing methods. It demonstrates the potential of using frequency-based monitoring technique for early-stage delamination detection in civil structures.
COMPOSITE STRUCTURES
(2022)
Article
Orthopedics
Han Eol Cho, Won Ah Choi, Sang-Yoep Lee, Seong-Woong Kang
Summary: This study aimed to standardize the method of air stacking by identifying the optimal pressure and number of squeezes performed by professional physicians, and to investigate the current status of air stacking implementation in patients. The study found that caregivers often perform air stacking inappropriately, leading to complications, and introduced a new method, manometry, to achieve optimal air stacking.
Article
Physics, Multidisciplinary
Andrey Melnikov, Alison E. Malcolm, Kristin M. Poduska
Summary: A comparison of three different isotropic non-linear elastic models reveals subtle differences in the acoustoelastic responses of a material slab during a pump-probe experiment, highlighting the importance of accurately predicting probe wave speeds under different pump wave types.
Article
Engineering, Biomedical
Girish B. Nair, Sayf Al-Katib, Robert Podolsky, Thomas Quinn, Craig Stevens, Edward Castillo
Summary: This study introduces a novel method for computing dynamic lung compliance imaging from CT scans to monitor compliance in patients with lung disease. Results show that patients with idiopathic pulmonary fibrosis have significantly lower LCI values compared to non-IPF patients.
PHYSICS IN MEDICINE AND BIOLOGY
(2021)
Article
Engineering, Geological
Samuel Chapman, Jerome Fortin, Ariel Gallagher, Jan V. M. Borgomano
Summary: Numerous experimental studies have shown that there are significant differences between the static and dynamic elastic moduli of rocks, which are attributed to the presence of cracks and uncemented grain contacts. This study investigated the impact of strain amplitude on the bulk modulus of different rock types and observed a transition from dynamic to static modulus with increasing strain amplitude. The presence of slip at grain contacts explains this transition.
ROCK MECHANICS AND ROCK ENGINEERING
(2023)
Article
Cardiac & Cardiovascular Systems
Ahmet Baydur, Richard Barbers, Darren May
Summary: Bronchial thermoplasty (BT) reduces bronchoconstriction and symptoms in severe asthmatics, but has little effect on spirometric variables. This study evaluated the changes in lung compliance and resistance before and after BT using the esophageal balloon technique. The results showed improvement in symptoms and variations in dynamic lung compliance and resistance among patients.
RESPIRATORY MEDICINE
(2023)
Article
Computer Science, Interdisciplinary Applications
Jovana Andrejevic, Chris H. Rycroft
Summary: This work presents a method for simulating the deformation and crumpling of thin, elastoplastic sheets. Two different formulations, quasistatic and dynamic, are used to describe the motion of the sheets. The method shows effectiveness in simulating various crumpling phenomena and is consistent with experimental observations.
JOURNAL OF COMPUTATIONAL PHYSICS
(2022)
Article
Engineering, Multidisciplinary
Javad Ghorbani, Majidreza Nazem, Jayantha Kodikara, Peter Wriggers
Summary: By employing a mortar-type contact algorithm, a theoretical and numerical framework was developed for elastoplastic interaction of unsaturated granular soils with a rigid cylindrical object. The constitutive model based on the effective stress concept offers the ability to simulate the effect of stress-induced anisotropy on the plastic response, as demonstrated in several numerical examples for verification and sensitivity analysis.
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING
(2021)
Article
Engineering, Multidisciplinary
H. Wei, J. L. Zheng, J. Sladek, V. Sladek, P. H. Wen
Summary: This paper presents the development of Erdogans fundamental solution (MFS) method for solving a 2D in-plane crack problem under static and dynamic loads. Erdogan's analytical solutions for a cracked infinite domain with static concentrated force using complex variables are extended to 2D elasticity. Both Laplace transform technique and Durbin inversion technique are used to determine the time-dependent variables in the case of dynamic loads. The accuracy and convergence of the MFS are demonstrated through numerical examples, with comparisons to analytical solutions and finite element method.
ENGINEERING ANALYSIS WITH BOUNDARY ELEMENTS
(2023)
Article
Physiology
Magali Boucher, Cyndi Henry, Fatemeh Khadangi, Alexis Dufour-Mailhot, Sophie Tremblay-Pitre, Liah Fereydoonzad, David Brunet, Annette Robichaud, Ynuk Bosse
Summary: The study found that LPS and methacholine challenges both increased static elastance (E-st); LPS decreased A but did not affect K, while methacholine decreased both A and K in the multiple-dose challenge and decreased K but not A in the single-dose challenge. These results suggest that lung tissue compliance, assessed using the parameter K of Salazar-Knowles' equation, is insensitive to inflammation but sensitive to ASM contraction.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
(2022)
Article
Critical Care Medicine
Erik Norberg, Helena Odenstedt-Herges, Bertil Rydenhag, Jonatan Oras
NEUROCRITICAL CARE
(2018)
Article
Anesthesiology
K. Lowhagen, S. Lindgren, H. Odenstedt, O. Stenqvist, S. Lundin
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2011)
Article
Anesthesiology
B. Andersson, S. Lundin, S. Lindgren, O. Stenqvist, H. Odenstedt Herges
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2011)
Article
Anesthesiology
K. Lowhagen, S. Lindgren, H. Odenstedt, O. Stenqvist, S. Lundin
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2011)
Article
Anesthesiology
L. Sand, M. Rizell, E. Houltz, K. Karlsen, J. Wiklund, H. Odenstedt Herges, O. Stenqvist, S. Lundin
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2011)
Article
Behavioral Sciences
Ann Sorbo, Ingrid Eiving, Pia Lowhagen Henden, Silvana Naredi, Johan Ljungqvist, Helena Odenstedt Herges
BRAIN AND BEHAVIOR
(2019)
Article
Anesthesiology
Linda Block, Max Petzold, Alma Nordenskjoeld Syrous, Birgitta Lindqvist, Helena Odenstedt Herges, Silvana Naredi
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2019)
Article
Anesthesiology
Sandra Bjerkne Wenneberg, Pia M. Lowhagen Henden, Jonatan Oras, Silvana Naredi, Linda Block, Johan Ljungqvist, Helena Odenstedt Herges
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2020)
Article
Anesthesiology
Linda Block, Ali El-Merhi, Jaquette Liljencrantz, Silvana Naredi, Miroslaw Staron, Helena Odenstedt Herges
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2020)
Article
Clinical Neurology
Sandra Bjerkne Wenneberg, Helena Odenstedt Herges, Pernilla Svedin, Carina Mallard, Thomas Karlsson, Martin Adiels, Silvana Naredi, Linda Block
Summary: The study identified an association between elevated serum concentrations of inflammatory markers and poor neurological outcome 1-year after aSAH. However, these results may be influenced by other clinical events, and after adjustments, only IL-1Ra remained significantly associated with poor outcome. Further testing in larger trials is needed to confirm the robustness of these findings.
ACTA NEUROLOGICA SCANDINAVICA
(2021)
Article
Anesthesiology
Alma Nordenskjold Syrous, Johan Malmgren, Helena Odenstedt Herges, Sepideh Olausson, Maria Kock-Redfors, Anders Agard, Linda Block
Summary: This study investigates factors contributing to physician-related variability in end-of-life decision-making, identifying different assessments of patient preferences, intensivists' personalities and values, and strategies for avoiding criticism and conflicts as key factors. The ethical challenges faced by intensivists have been exacerbated by the COVID-19 pandemic, highlighting the importance of addressing variability in end-of-life decision-making in a formal and transparent manner.
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2021)
Article
Emergency Medicine
Djino Khaki, Virpi Hietanen, Alba Corell, Helena Odenstedt Herges, Johan Ljungqvist
Summary: Traumatic brain injuries (TBI) are often associated with high morbidity and mortality rates. This study aimed to analyze different CT classification systems and prognostic calculators in a representative population of TBI patients, finding that the Stockholm CT score showed the strongest relationship to actual outcomes and would be the preferred method for continued research using CT score models.
SCANDINAVIAN JOURNAL OF TRAUMA RESUSCITATION & EMERGENCY MEDICINE
(2021)
Article
Clinical Neurology
Helena Odenstedt Herges, Richard Vithal, Ali El-Merhi, Silvana Naredi, Miroslaw Staron, Linda Block
Summary: This study analyzed HRV data from aSAH patients using machine learning to identify specific patterns in patients developing DCI. While the machine learning process identified 71% of all DCI cases, it also demonstrated a low specificity in identifying DCI in non-DCI patients. Further research is needed to develop a robust method for detecting DCI using real-time HRV data.
ACTA NEUROLOGICA SCANDINAVICA
(2022)
Article
Clinical Neurology
Sandra Bjerkne Wenneberg, Linda Block, Ann Sorbo, Silvana Naredi, Jonatan Oras, Pia Lowhagen Henden, Johan Ljungqvist, Jaquette Liljencrantz, Helena Odenstedt Herges
Summary: This study aimed to evaluate long-term outcomes for patients with aSAH at 1 and 3 years, finding improvements and deteriorations in patient conditions. It revealed cognitive dysfunction, particularly mental fatigue, common in aSAH patients, impacting quality of life and recovery, emphasizing the importance of longer follow-up periods and broad outcome assessments.
ACTA NEUROLOGICA SCANDINAVICA
(2022)
Article
Anesthesiology
Alma Nordenskjold Syrous, Gudny Gudnadottir, Jonatan Oras, Thalia Ferguson, David Lilja, Helena Odenstedt Herges, Emma Larsson, Linda Block
Summary: This study aimed to compare end-of-life decision making in critically ill patients with COVID-19 and patients with other diagnoses. It found that the Charlson comorbidity index was independently associated with the decision to withdraw or withhold life-sustaining treatments in COVID-19 patients, while age and SAPS 3 were associated with the decision in non-COVID-19 patients.
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2023)