Article
Multidisciplinary Sciences
Young-Ah Choi, Jung Soo Lee, Yeo Hyung Kim
Summary: We investigated the association between physical activity level and dynapenia in older adults with COPD and found that higher physical activity levels were associated with lower odds of dynapenia. This association was observed only in male patients and individuals with normal weight.
SCIENTIFIC REPORTS
(2022)
Article
Public, Environmental & Occupational Health
Yan Du, Tao Xu, Zenong Yin, Sara Espinoza, Yiqiong Xie, Caleb Gentry, Qing Tian, Lan-Juan Zhao, Hui Shen, Zhe Luo, Hong-Wen Deng
Summary: This study examined the associations between physical activity, obesity, and sarcopenia in middle-aged and older adults. The results showed that the associations varied considerably across gender and age groups. Higher frequency of exercise was associated with lower likelihood of obesity, sarcopenia, and sarcopenia obesity in all groups.
Article
Nutrition & Dietetics
Pablo Jorge Marcos-Pardo, Noelia Gonzalez-Galvez, Abraham Lopez-Vivancos, Alejandro Espeso-Garcia, Luis Manuel Martinez-Aranda, Gemma Maria Gea-Garcia, Francisco Javier Orquin-Castrillon, Ana Carbonell-Baeza, Jose Daniel Jimenez-Garcia, Daniel Velazquez-Diaz, Cristina Cadenas-Sanchez, Emanuele Isidori, Chiara Fossati, Fabio Pigozzi, Lorenzo Rum, Catherine Norton, Audrey Tierney, Ilvis Abelkalns, Agita Klempere-Sipjagina, Juris Porozovs, Heikki Hannola, Niko Niemisalo, Leo Hokka, David Jimenez-Pavon, Raquel Vaquero-Cristobal
Summary: The study determined the prevalence of sarcopenia among European middle-aged and older adults, finding that factors such as being male, age under 65, lower BMI, high levels of vigorous physical activity, and dietary habits could affect the risk of developing sarcopenia.
Article
Health Care Sciences & Services
Hamza Ferhi, Sabri Gaied Chortane, Sylvain Durand, Bruno Beaune, Sebastien Boyas, Wael Maktouf
Summary: This study aimed to investigate the effect of a 24-week posture, strengthening, and motricity program on gait parameters and neuromuscular strategies in older adults with sarcopenic obesity. The trained group showed significant improvements in walking speed, step length, and center of pressure velocity, along with decreased muscle activity during different gait phases. These findings highlight the effectiveness of the program in improving gait and neuromuscular capacities in older adults with sarcopenic obesity.
Article
Physiology
Hun-Young Park, Won-Sang Jung, Sung-Woo Kim, Kiwon Lim
Summary: Among elderly people in Korea, higher levels of physical activity were associated with lower prevalence of cardiometabolic disease, osteoporosis, sarcopenia, obesity, and sarcopenic obesity.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Geriatrics & Gerontology
Ippei Chiba, Sangyoon Lee, Seongryu Bae, Keitaro Makino, Yohei Shinkai, Osamu Katayama, Kenji Harada, Naoto Takayanagi, Hiroyuki Shimada
Summary: The study found that for older adults with sarcopenia, higher levels of light-intensity physical activity were associated with a lower risk of disability, while moderate-to-vigorous intensity physical activity was associated with a lower risk of disability in those with robust and low physical function. This highlights the need for individualized approaches to disability prevention based on muscle condition.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2021)
Article
Nutrition & Dietetics
Yanjie Zhang, Xiaolei Liu, Yongzhi Ma, Xinxing Li
Summary: The purpose of this study was to investigate the association between moderate to vigorous physical activity (MVPA), sedentary behavior, fruit and vegetable intake, and the risk of sarcopenia among older Chinese adults. The results showed that only 32.63% of the participants met the recommendations for MVPA, sedentary behavior, and fruit and vegetable intake, and meeting these recommendations was associated with a lower risk of sarcopenia.
Article
Nutrition & Dietetics
Han-Sol Lim, Dong-Kun Kim, Hyun-Il Gil, Mi-Yeon Lee, Hyun-Seung Lee, Yong-Taek Lee, Kyung Jae Yoon, Chul-Hyun Park
Summary: Osteosarcopenic obesity (OSO) is a newly described condition characterized by the coexistence of osteopenia/osteoporosis, sarcopenia, and obesity. In this study, we investigated the relationship between pulmonary function, OSO, and its composition in adults aged 50 years and above. The results showed that as the number of abnormal body compositions increased, forced volume vital capacity (FVC)%, forced expiratory volume in 1 s (FEV1)%, and FEV1/FVC% significantly decreased. Furthermore, the prevalence of restrictive spirometry pattern (RSP) was positively associated with a higher number of abnormal body composition parameters.
Article
Multidisciplinary Sciences
Nils Georg Niederstrasser, Nina Attridge
Summary: The study found that high levels of physical activity were associated with a reduced risk of suffering from musculoskeletal pain. In addition, low wealth, being female, and being overweight or obese were identified as risk factors for musculoskeletal pain.
Article
Nutrition & Dietetics
Javier Conde-Pipo, Cristina Bouzas, Felix Zurita-Ortega, Fatima Olea-Serrano, Josep A. Tur, Miguel Mariscal-Arcas
Summary: The study found that non-adherence to the Mediterranean dietary pattern and low levels of physical activity are associated with lower levels of physical self-concept in older adults.
Article
Geriatrics & Gerontology
Saliu A. Balogun, Dawn Aitken, Feitong Wu, David Scott, Graeme Jones, Tania Winzenberg
Summary: This study aimed to describe the relationships between physical activity, body composition, and multimorbidity over 10 years in older adults. The results showed a nonlinear relationship between physical activity level and multimorbidity, with lower risk associated with less steps per day, as well as linear associations between higher BMI, fat mass, lower grip strength, and lean mass with higher risk of multimorbidity. Maintaining adequate physical activity levels and muscle function while reducing adiposity may help minimize the risk of multimorbidity in older adults.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Geriatrics & Gerontology
Ewelina Akehurst, David Scott, Juan Pena Rodriguez, Carol Alonso Gonzalez, Jasmaine Murphy, Helen McCarthy, Sandor Dorgo, Alan Hayes
Summary: The study found that older adults attending HUR and conventional gyms had similar self-reported function and nutrition (but different protein intake levels). Inadequate physical activity was associated with decreased gait speed, while inadequate nutrition and low protein intake were associated with decreased lean mass.
Article
Geriatrics & Gerontology
Louis Jacob, Razak M. M. Gyasi, Hans Oh, Lee Smith, Karel Kostev, Guillermo F. Lopez F. Sanchez, Masoud Rahmati, Josep Maria Haro, Mark A. A. Tully, Jae Il Shin, Dong Keon Yon, Ai Koyanagi
Summary: This study found a significant association between leisure-time physical activity (LTPA) and sarcopenia in older adults from low- and middle-income countries (LMICs). Analyzing data from six LMICs, the study showed that low LTPA was associated with higher odds of sarcopenia, particularly in women.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Nutrition & Dietetics
Molly Curtis, Lauren Swan, Rebecca Fox, Austin Warters, Maria O'Sullivan
Summary: This study found a significant association between low body mass index (BMI) and probable sarcopenia, highlighting a high-risk group. However, there were conflicting findings regarding the association between overweight/obesity and probable sarcopenia. It is recommended to assess all older adults at risk of probable sarcopenia, including those with overweight/obesity, to prevent underdetection or the double burden of obesity and sarcopenia.
Review
Cell Biology
Helio Jose Coelho-Junior, Riccardo Calvani, Matteo Tosato, Francesco Landi, Anna Picca, Emanuele Marzetti
Summary: The study found that a protein intake higher than the recommended dietary allowance is cross-sectionally associated with better physical performance and greater muscle strength in older adults. However, over time, a high consumption of proteins does not seem to prevent decline in physical function.
AGEING RESEARCH REVIEWS
(2022)
Review
Endocrinology & Metabolism
A. -L. Borel, R. Tamisier, P. Bohme, P. Priou, A. Avignon, P. -Y. Benhamou, H. Hanaire, J. -L. Pepin, L. Kessler, P. Valensi, P. Darmon, F. Gagnadoux
DIABETES & METABOLISM
(2019)
Article
Respiratory System
A. -L. Borel, R. Tamisier, P. Bohme, P. Priou, A. Avignon, P. -Y. Benhamou, H. Hanaire, J. -L. Pepin, L. Kessler, P. Valensi, P. Darmon, F. Gagnadoux
REVUE DES MALADIES RESPIRATOIRES
(2018)
Editorial Material
Endocrinology & Metabolism
A. J. Scheen, P. Darmon, H. Hanaire, B. Bauduceau, L. Bordier, G. Chabrier, B. Charbonnel, B. Detournay, P. Fontaine, P. Gourdy, A. Grimaldi, B. Guerci, A. Pernfornis, J. P. Riveline
DIABETES & METABOLISM
(2019)
Editorial Material
Cardiac & Cardiovascular Systems
Lisa Ludwig, Patrice Darmon, Bruno Guerci
CARDIOVASCULAR DIABETOLOGY
(2020)
Article
Endocrinology & Metabolism
Bertrand Cariou, Samy Hadjadj, Matthieu Wargny, Matthieu Pichelin, Abdallah Al-Salameh, Ingrid Allix, Coralie Amadou, Gwenaelle Arnault, Florence Baudoux, Bernard Bauduceau, Sophie Borot, Muriel Bourgeon-Ghittori, Olivier Bourron, David Boutoille, France Cazenave-Roblot, Claude Chaumeil, Emmanuel Cosson, Sandrine Coudol, Patrice Darmon, Emmanuel Disse, Amelie Ducet-Boiffard, Benedicte Gaborit, Michael Joubert, Veronique Kerlan, Bruno Laviolle, Lucien Marchand, Laurent Meyer, Louis Potier, Gaetan Prevost, Jean-Pierre Riveline, Rene Robert, Pierre-Jean Saulnier, Ariane Sultan, Jean-Francois Thebaut, Charles Thivolet, Blandine Tramunt, Camille Vatier, Ronan Roussel, Jean-Francois Gautier, Pierre Gourdy
Correction
Endocrinology & Metabolism
Bertrand Cariou, Samy Hadjadj, Matthieu Wargny, Matthieu Pichelin, Abdallah Al-Salameh, Ingrid Allix, Coralie Amadou, Gwenaelle Arnault, Florence Baudoux, Bernard Bauduceau, Sophie Borot, Muriel Bourgeon-Ghittori, Olivier Bourron, David Boutoille, France Cazenave-Roblot, Claude Chaumeil, Emmanuel Cosson, Sandrine Coudol, Patrice Darmon, Emmanuel Disse, Amelie Ducet-Boiffard, Benedicte Gaborit, Michael Joubert, Veronique Kerlan, Bruno Laviolle, Lucien Marchand, Laurent Meyer, Louis Potier, Gaetan Prevost, Jean-Pierre Riveline, Rene Robert, Pierre-Jean Saulnier, Ariane Sultan, Jean-Francois Thebaut, Charles Thivolet, Blandine Tramunt, Camille Vatier, Ronan Roussel, Jean-Francois Gautier, Pierre Gourdy
Editorial Material
Endocrinology & Metabolism
Matthieu Wargny, Pierre Gourdy, Lisa Ludwig, Dominique Seret-Begue, Olivier Bourron, Patrice Darmon, Coralie Amadou, Matthieu Pichelin, Louis Potier, Charles Thivolet, Jean-Francois Gautier, Samy Hadjadj, Bertrand Cariou
Letter
Endocrinology & Metabolism
Bertrand Cariou, Samy Hadjadj, Matthieu Wargny, Matthieu Pichelin, Abdallah Al-Salameh, Ingrid Allix, Coralie Amadou, Gwenaelle Arnault, Florence Baudoux, Bernard Bauduceau, Sophie Borot, Muriel Bourgeon-Ghittori, Olivier Bourron, David Boutoille, France Cazenave-Roblot, Claude Chaumeil, Emmanuel Cosson, Sandrine Coudol, Patrice Darmon, Emmanuel Disse, Amelie Ducet-Boiffard, Benedicte Gaborit, Michael Joubert, Veronique Kerlan, Bruno Laviolle, Lucien Marchand, Laurent Meyer, Louis Potier, Gaetan Prevost, Jean-Pierre Riveline, Rene Robert, Pierre-Jean Saulnier, Ariane Sultan, Jean-Francois Thebaut, Charles Thivolet, Blandine Tramunt, Camille Vatier, Ronan Roussel, Jean-Francois Gautier, Pierre Gourdy
Article
Medicine, General & Internal
Adele Lasbleiz, Bertrand Cariou, Patrice Darmon, Astrid Soghomonian, Patricia Ancel, Sandrine Boullu, Marie Houssays, Fanny Romain, Jean Christophe Lagier, Mohamed Boucekine, Noemie Resseguier, Pierre Gourdy, Matthieu Pichelin, Matthieu Wargny, Anne Dutour, Benedicte Gaborit
JOURNAL OF CLINICAL MEDICINE
(2020)
Article
Cardiac & Cardiovascular Systems
B. Gaborit, P. Ancel, A. E. Abdullah, F. Maurice, I. Abdesselam, A. Calen, A. Soghomonian, M. Houssays, I. Varlet, M. Eisinger, A. Lasbleiz, F. Peiretti, C. E. Bornet, Y. Lefur, L. Pini, S. Rapacchi, M. Bernard, N. Resseguier, P. Darmon, F. Kober, A. Dutour
Summary: Empagliflozin effectively reduced liver fat in mice and humans without impacting myocardial fat or myocardial energetics, contradicting the thrifty substrate hypothesis for cardiovascular protection of SGLT2 inhibitors.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Endocrinology & Metabolism
Ronan Roussel, Patrice Darmon, Matthieu Pichelin, Thomas Goronflot, Yawa Abouleka, Leila Ait Bachir, Ingrid Allix, Deborah Ancelle, Sara Barraud, Lyse Bordier, Aurelie Carlier, Nicolas Chevalier, Christine Coffin-Boutreux, Emmanuel Cosson, Anne Dorange, Olivier Dupuy, Pierre Fontaine, Benedicte Fremy, Florence Galtier, Natacha Germain, Anne-Marie Guedj, Etienne Larger, Stephanie Laugier-Robiolle, Bruno Laviolle, Lisa Ludwig, Arnaud Monier, Nathanaelle Montanier, Philippe Moulin, Isabelle Moura, Gaetan Prevost, Yves Reznik, Nadia Sabbah, Pierre-Jean Saulnier, Pierre Serusclat, Camille Vatier, Matthieu Wargny, Samy Hadjadj, Pierre Gourdy, Bertrand Cariou
Summary: A study on 2449 type 2 diabetes patients with COVID-19 found no significant association between the use of DPP-4 inhibitors and disease severity. Therefore, it is safe to continue using DPP-4 inhibitors for diabetes management during the COVID-19 pandemic.
DIABETES OBESITY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Matthieu Wargny, Louis Potier, Pierre Gourdy, Matthieu Pichelin, Coralie Amadou, Pierre-Yves Benhamou, Jean-Baptiste Bonnet, Lyse Bordier, Olivier Bourron, Claude Chaumeil, Nicolas Chevalier, Patrice Darmon, Blandine Delenne, Delphine Demarsy, Marie Dumas, Olivier Dupuy, Anna Flaus-Furmaniuk, Jean-Francois Gautier, Anne-Marie Guedj, Nathalie Jeandidier, Etienne Larger, Jean-Philippe Le Berre, Myriam Lungo, Nathanaelle Montanier, Philippe Moulin, Francoise Plat, Vincent Rigalleau, Rene Robert, Dominique Seret-Begue, Pierre Serusclat, Sarra Smati, Jean-Francois Thebaut, Blandine Tramunt, Camille Vatier, Fritz-Line Velayoudom, Bruno Verges, Patrice Winiszewski, Audrey Zabulon, Pierre-Antoine Gourraud, Ronan Roussel, Bertrand Cariou, Samy Hadjadj
Summary: The study identified prognostic factors for hospital discharge and death in patients with diabetes hospitalized for COVID-19, finding that younger age, routine metformin therapy, longer symptom duration on admission were positively associated with discharge, while history of microvascular complications, anticoagulant routine therapy, dyspnoea on admission, and higher levels of certain biomarkers were associated with reduced chance of discharge.
Article
Cardiac & Cardiovascular Systems
Ofri Mosenzon, Abdullah Alguwaihes, Jose Luis Arenas Leon, Fahri Bayram, Patrice Darmon, Timothy M. E. Davis, Guillermo Dieuzeide, Kirsten T. Eriksen, Tianpei Hong, Margit S. Kaltoft, Csaba Lengyel, Nicolai A. Rhee, Giuseppina T. Russo, Shinichiro Shirabe, Katerina Urbancova, Sergio Vencio
Summary: The CAPTURE study aimed to estimate the prevalence of established cardiovascular disease in adults with type 2 diabetes across 13 countries from five continents, and to further characterize the study sample regarding demographics, clinical parameters, and medication usage, particularly focusing on glucose-lowering agents with demonstrated cardiovascular benefits.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Patrick Blin, Patrice Darmon, Patrick Henry, Estelle Guiard, Marie-Agnes Bernard, Caroline Dureau-Pournin, Helene Maizi, Florence Thomas-Delecourt, Regis Lassalle, Cecile Droz-Perroteau, Nicholas Moore
Summary: The study compared the efficacy of ticagrelor plus aspirin versus placebo plus aspirin for patients with stable coronary artery disease and type 2 diabetes mellitus, finding a prevalence of 1.5‰ for the THEMIS-like population in French practice, with a median age 5-6 years older than the study group, and significantly higher incidence rates of major outcomes over 2 years compared to the placebo arm of the THEMIS trial.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Medicine, General & Internal
Thierry Hannedouche, Patrick Rossignol, Patrice Darmon, Jean-Michel Halimi, Patrick Vuattoux, Albert Hagege, Ludivine Videloup, Francis Guinard
Summary: Diabetes is the leading cause of end-stage kidney disease (ESKD), accounting for approximately 50% of patients starting dialysis. However, the management of patients with chronic kidney disease (CKD) remains poor, and there are fragmented care pathways among healthcare professionals (HCPs). Laboratory evidence, such as estimated glomerular filtration rate (eGFR), urine albumin-to-creatinine ratio (UACR), Kidney Failure Risk Equation (KFRE), and serum potassium, plays a crucial role in the diagnosis and monitoring of CKD and its complications.
POSTGRADUATE MEDICINE
(2023)