Article
Chemistry, Multidisciplinary
Han Gao, Lingfei Hu, Yanlei Hu, Xiangying Lv, Yan-Bo Wu, Gang Lu
Summary: The origins of regioselectivity in Ni-catalyzed alkene hydrofunctionalizations were computationally investigated using energy decomposition analysis. The results indicate that the Markovnikov selectivity with aryl-substituted alkenes is favored due to the stabilizing charge transfer effect, while the anti-Markovnikov selectivity with alkyl-substituted alkenes is favored because of the destabilizing Pauli repulsion effect.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Gayathri B. Gange, Amanda L. Humphries, Mark D. Smith, Dmitry V. Peryshkov
Summary: In this study, we report the reactivity of carboranyl diphosphine with terminal alkynes, resulting in the formation of boron-containing phosphacycles. The reaction combines the activation of electron-deficient alkynes by phosphine groups and the redox behavior of carborane clusters, leading to the formation of a fused product of alkenylphosphonium cycle and reduced carborane cluster.
INORGANIC CHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Antonio Zucca, Maria I. Pilo
Summary: Rollover cyclometalation is a unique reaction where a chelated heterocyclic ligand undergoes internal rotation to activate a remote C-H bond, forming a novel cyclometalated complex with unique properties. The rollover ligand, with an uncoordinated donor atom, displays multiple personalities and enables a series of distinct reactions, leading to potential applications in catalysis, organic synthesis, and advanced materials.
Article
Chemistry, Organic
Shang-You Sun, Selvam Raju, Guganchandar Vedarethinam, Pei-Lin Chen, Shih-Ching Chuang
Summary: The reaction of o-benzofulvene with TfOH leads to intramolecular cyclization through novel C-C and C-N bond formation, resulting in the formation of a new molecular framework with reasonable to excellent yields. The method tolerates various electron-withdrawing/donating substituents and exhibits high diastereoselectivity. Additionally, it is free of bases, oxidants, and metals, and proceeds under mild reaction conditions favorable for synthetic organic chemistry.
Article
Chemistry, Multidisciplinary
Daigo Hayashi, Tomohiro Tsuda, Ryo Shintani
Summary: A palladium-catalyzed skeletal rearrangement has been developed to synthesize highly fused tetrahydrophenanthrosilole derivatives via bond exchange. The reaction conditions can be tuned to produce different products, fused dihydrodibenzosilepin derivatives.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Multidisciplinary Sciences
Suman K. Barman, Meng-Yin Yang, Trenton H. Parsell, Michael T. Green, A. S. Borovik
Summary: This study explores the mechanism of metal-oxido species in C-H bond cleavage, highlighting the importance of basicity in achieving enzymatic function. The research found that proton transfer plays a more dominant role than electron transfer in these reactions.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Chemistry, Multidisciplinary
Lili Fang, Shuaixin Fan, Weiping Wu, Tielei Li, Jin Zhu
Summary: A low-cost, room temperature ruthenium catalytic method was developed for the synthesis of delta-diketones by coupling alpha-keto sulfoxonium ylides with cyclopropanols. The mild protocol showed a broad substrate scope (47 examples) and high product yield (up to 99%), with mechanistic studies supporting a cyclopropanol ring opening, sulfoxonium ylide-derived carbenoid formation, migratory insertion C-C bond formation pathway.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Physical
Samuel Hruby, Jan Ulc, Ivana Cisarova, Martin Kotora
Summary: The scope of Rh-catalyzed C-C bond cleavage/annulation of biphenylene with various aromatic nitriles was investigated. Further Rh- and Ir-catalyzed C-H bond activation/annulation sequence of the resulting 9-arylphenanthridines with alkynes led to the formation of cationic [4], [5], [6] helical quinolizinium salts. The helical arrangement of these compounds was confirmed by single-crystal X-ray analysis. Most of the prepared quinolizinium salts exhibited fluorescence emission with a maximum wavelength in the range of 525-623 nm and absolute quantum yields up to 25%.
Review
Chemistry, Multidisciplinary
Bo Su, John F. Hartwig
Summary: This review discusses the rapid development and significance of enantioselective silylation and borylation of C-H bonds, emphasizing the importance of designing and developing chiral ligands for these reactions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
David Gygi, Miguel Gonzalez, Seung Jun Hwang, Kay T. Xia, Yangzhong Qin, Elizabeth J. Johnson, Francois Gygi, Yu-Sheng Chen, Daniel G. Nocera
Summary: This study overcomes the challenge of activating C-H bonds by synthesizing a specific complex that generates a chlorine radical under light irradiation. The experimental and computational results together reveal the complete reaction profile for the preferential activation of a C-H bond in the solid state.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Review
Spectroscopy
Richard A. J. O'Hair
Summary: Carboxylic acids are valuable organic substrates due to their wide availability, easy handling, and structural diversity. Studies over the past two decades have explored new modes of metal-mediated reactivity of carboxylic acids and their derivatives, with mass spectrometry-based studies providing insights into these new reaction pathways. Recent research highlights the potential role of mechanistic studies integrating both gas- and condensed-phase studies.
MASS SPECTROMETRY REVIEWS
(2021)
Article
Chemistry, Organic
Ran Fang, Lin Zhou, Alexander M. Kirillov, Lizi Yang
Summary: The DFT study investigated a zirconium-catalyzed hydroaminoalkylation reaction, revealing the electrophilic nature of the substrates and the nucleophilic behavior of the zirconaaziridine catalyst. The distortion/interaction analysis showed how distortion and interaction energies control regioselectivity and diastereoselectivity with different alkene substrates. These findings offer insights into the substrate-dependent product selectivity in the reaction.
Review
Chemistry, Inorganic & Nuclear
Seiji Ogo, Takeshi Yatabe, Hidetaka Nakai
Summary: This review discusses whether the ligand design used in catalysts mimicking O2-tolerant [NiFe] hydrogenase can be applied to ligand design in catalysts for C-C bond forming reactions. It explores the possibility of applying the ligand design methodology in reductive C-C coupling and C-H arylation reactions.
COORDINATION CHEMISTRY REVIEWS
(2022)
Article
Chemistry, Multidisciplinary
Chamila Manankandayalage, Daniel K. Unruh, Clemens Krempner
Summary: The intramolecular inverse frustrated Lewis pairs (FLPs) with weakly Lewis acidic boryl and strongly basic guanidino moieties were synthesized and characterized, demonstrating their capability to activate small molecules. These novel FLPs show promising potential in diverse chemical transformations.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Organic
Cheng-Hao Gu, Zhen Zhang, Shuo-Jie Shen, Hua-Jin Xu, Yi Hu
Summary: To further promote the practical application of C-H activation, researchers aim to develop green and mild reaction conditions, especially for remote C-H activation reactions. In this study, a new cheap and powerful (n-Bu)4NNO3 oxidant was reported, which enables Pd(II) catalyzed sp2 and sp3 C-H olefination at room temperature. This advancement contributes to making C-H functionalization more economical and environmentally benign.
Article
Biochemistry & Molecular Biology
Jeremiah N. Betz, Nicholas W. Boswell, Corey J. Fugate, Gemma L. Holliday, Eyal Akiva, Anna G. Scott, Patricia C. Babbitt, John W. Peters, Eric M. Shepard, Joan B. Broderick
Review
Biochemistry & Molecular Biology
John W. Peters, Gerrit J. Schut, Eric S. Boyd, David W. Mulder, Eric M. Shepard, Joan B. Broderick, Paul W. King, Michael W. W. Adams
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2015)
Editorial Material
Biochemistry & Molecular Biology
Roland Lill, Joan B. Broderick, Dennis R. Dean
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
(2015)
Article
Chemistry, Multidisciplinary
Kevin D. Swanson, Michael W. Ratzloff, David W. Mulder, Jacob H. Artz, Shourjo Ghose, Andrew Hoffman, Spencer White, Oleg A. Zadvornyy, Joan B. Broderick, Brian Bothner, Paul W. King, John W. Peters
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2015)
Article
Chemistry, Multidisciplinary
Masaki Horitani, Amanda S. Byer, Krista A. Shisler, Tilak Chandra, Joan B. Broderick, Brian M. Hoffrnan
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2015)
Review
Biochemistry & Molecular Biology
Krista A. Shisler, Joan B. Broderick
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2014)
Article
Biochemistry & Molecular Biology
Eric M. Shepard, Florence Mus, Jeremiah N. Betz, Amanda S. Byer, Benjamin R. Duffus, John W. Peters, Joan B. Broderick
Review
Chemistry, Multidisciplinary
Joan B. Broderick, Benjamin R. Duffus, Kaitlin S. Duschene, Eric M. Shepard
Article
Biochemistry & Molecular Biology
Shourjo Ghose, Jonathan K. Hilmer, Brian Bothner, Joan B. Broderick
Article
Biochemistry & Molecular Biology
Adam V. Crain, Joan B. Broderick
JOURNAL OF BIOLOGICAL CHEMISTRY
(2014)
Review
Biochemistry & Molecular Biology
Amanda S. Byer, Eric M. Shepard, John W. Peters, Joan B. Broderick
JOURNAL OF BIOLOGICAL CHEMISTRY
(2015)
Article
Biochemistry & Molecular Biology
Sunshine C. Silver, David J. Gardenghi, Sunil G. Naik, Eric M. Shepard, Boi Hanh Huynh, Robert K. Szilagyi, Joan B. Broderick
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
(2014)
Review
Biochemistry & Molecular Biology
Joan B. Broderick, Amanda S. Byer, Kaitlin S. Duschene, Benjamin R. Duffus, Jeremiah N. Betz, Eric M. Shepard, John W. Peters
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
(2014)
Article
Chemistry, Multidisciplinary
David W. Mulder, Michael W. Ratzloff, Eric M. Shepard, Amanda S. Byer, Seth M. Noone, John W. Peters, Joan B. Broderick, Paul W. King
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2013)
Article
Chemistry, Multidisciplinary
Benjamin R. Duffus, Shourjo Ghose, John W. Peters, Joan B. Broderick
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2014)
