期刊
CURRENT OPINION IN CELL BIOLOGY
卷 25, 期 3, 页码 378-386出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2013.03.002
关键词
-
类别
资金
- American Heart Association [10SDG2610290]
- Pew Charitable Trust
Maintaining genome integrity is crucial for successful organismal propagation and for cell and tissue homeostasis. Several processes contribute to safeguarding the genomic information of cells. These include accurate replication of genetic information, detection and repair of DNA damage, efficient segregation of chromosomes, protection of chromosome ends, and proper organization of genome architecture. Interestingly, recent evidence shows that nuclear pore complexes, the channels connecting the nucleus with the cytoplasm, play important roles in these processes suggesting that these multiprotein platforms are key regulators of genome integrity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据