期刊
CURRENT OPINION IN CELL BIOLOGY
卷 23, 期 5, 页码 615-620出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2011.04.001
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资金
- FWF [SFB021]
- Federal Ministry for Transport Innovation and Technology (BMVIT)
- Federal Ministry of Economics and Labour the Federal Ministry of Economy, Family and Youth (BMWA/BMWFJ)
- Tiroler Standortagentur
- HFSP
- COMET Center ONCOTYROL
- Austrian Science Fund (FWF) [Y444] Funding Source: Austrian Science Fund (FWF)
- Austrian Science Fund (FWF) [Y 444] Funding Source: researchfish
Cell migration is a complex biological process that is under the tight control of diverse signaling events. While many of the involved signaling molecules diffuse rapidly within cells, it now seems that certain key regulators of cell migration prefer to travel on endosomes. In this review we will discuss the multiple roles of signaling endosomes in regulation of local migration stimuli, dynamics of focal adhesions, cell contractility and locomotion.
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