Editorial Material
Endocrinology & Metabolism
Kyriaki Kostoglou, David M. Simpson, Stephen J. Payne
Summary: Studies have shown evidence of asymmetry in the response of cerebral autoregulation (CA) to increasing and decreasing pressure challenges. CA appears to be stronger during transient increases in arterial blood pressure and weaker during decreases. The measurement of this effect and its relevance in clinical settings remain questionable.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Article
Obstetrics & Gynecology
Lina Bergman, Catherine Cluver, Niclas Carlberg, Michael Belfort, Mary C. Tolcher, Ronney B. Panerai, Teelkien van Veen
Summary: Dynamic cerebral autoregulation and cerebral perfusion pressure are altered in pregnancies complicated by preeclampsia, which may be important in the pathophysiological pathway and constitute a therapeutic target in the prevention of cerebral complications in preeclampsia.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Samuel P. Klein, Veerle De Sloovere, Geert Meyfroidt, Bart Depreitere
Summary: This study provides new insights into the quadriphasic physiology of cerebrovascular autoregulation (CA) and reveals substantial intersubject variability in the limits of CA.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Cardiac & Cardiovascular Systems
Rachel J. Skow, R. Matthew Brothers, Jurgen A. H. R. Claassen, Trevor A. Day, Caroline A. Rickards, Jonathan D. Smirl, Patrice Brassard
Summary: This article presents recommended terminology for reporting cerebral hemodynamic data and discusses the current use and misuse of terminology in the field. It provides guidelines for researchers in the study of cerebral hemodynamics.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2022)
Article
Clinical Neurology
Navpreet Reehal, Stephanie Cummings, Michael T. Mullen, Wesley B. Baker, David Kung, William Tackett, Christopher G. Favilla
Summary: This study compared cerebral autoregulation in all major cerebral vessels and found that while the time course of autoregulation was similar in all vessels, the magnitude of hemodynamic regulation was lower in the posterior cerebral artery. However, after adjusting for baseline flow differences, normalized gain was similar in all vessels.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Ashley M. Darling, Rauchelle E. Richey, John D. Akins, Erika F. H. Saunders, R. Matthew Brothers, Jody L. Greaney
Summary: In young adults with major depressive disorder (MDD), cerebral vasodilatory reactivity is blunted and further modulated by current depressive symptomology, suggesting that improving depressive symptoms may have a positive impact on cerebrovascular health.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Endocrinology & Metabolism
Yufan Wang, Stephen J. Payne
Summary: Cerebral autoregulation is the process by which cerebral blood flow remains constant in response to short-term variations in arterial blood pressure. Recent studies challenge the classic view that autoregulation remains constant over a wide range of blood pressure. A comprehensive literature research based on 143 studies found that there is a significant difference in the direction of blood flow sensitivity, with autoregulation being more effective in buffering increases in blood pressure. Regression analysis identified an autoregulatory plateau of approximately 20 mmHg, which is smaller than the widely accepted classical view. Age and sex were found to have no effect on autoregulation strength. This data-driven approach provides a quantitative method for analyzing static autoregulation.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Article
Clinical Neurology
Jie Pan, Huadong Wu, Tingting Wu, Yu Geng, Ruozhen Yuan
Summary: This study aimed to investigate the association between post-procedure cerebral blood flow velocity (CBFV) and severity of brain edema in patients with acute ischemic stroke (AIS) who received early endovascular therapy (EVT). The results suggest that the affected/contralateral ratio of CBFV may be a promising predictor of brain edema severity in patients with AIS who received early EVT.
FRONTIERS IN NEUROLOGY
(2022)
Article
Physiology
Sergei Valkov, Jan Harald Nilsen, Rizwan Mohyuddin, Torstein Schanche, Timofei Kondratiev, Gary C. Sieck, Torkjel Tveita
Summary: The efficacy of cerebral autoregulation during hypothermic CPR is largely unknown and is aim of the present experiment. The results showed that continuous CPR for 3 h at 27 degrees C provided sufficient cerebral oxygen delivery to maintain aerobic metabolism and preserve cerebral autoregulation during the first 2-h period of CPR.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biophysics
Joel S. Burma, Lauren N. Miutz, Kailey T. Newel, Lawrence Labrecque, Audrey Drapeau, Patrice Brassard, Paige Copeland, Alannah Macaulay, Jonathan D. Smirl
Summary: The study showed that valid and reliable dynamic cerebral autoregulation estimates can be obtained from shorter recording durations of squat-stand maneuvers, such as 180 or 240 seconds, when physiological covariates are controlled. However, future studies should aim for 300-second recordings to ensure optimal results.
PHYSIOLOGICAL MEASUREMENT
(2021)
Editorial Material
Endocrinology & Metabolism
Jia Liu, David M. Simpson, Ronney B. Panerai
Summary: This article discusses the method of using transfer function analysis (TFA) to assess dynamic cerebral autoregulation and highlights the issues with fixed banding in current methods. The authors provide evidence against fixed banding, suggest possible alternatives, and call for an open-minded approach to fully utilize the potential of TFA.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2023)
Article
Physiology
Eline Kho, Nicolaas H. Sperna Weiland, Alexander P. J. Vlaar, Denise P. Veelo, Bjorn J. P. van der Ster, Oskar T. Corsmit, Dave R. Koolbergen, Jose Dilai, Rogier Immink
Summary: This study assessed cerebral autoregulation during sustained hypotension, revealing its behavior during hypotension. Results showed that CA was disturbed during sustained hypotension but improved after blood pressure restoration, suggesting the absence of ischemic hyperemia and an unlikely adaptation mechanism during sustained hypotension.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Clinical Neurology
Stefan Duschek, Alexandra Hoffmann, Gustavo A. Reyes del Paso, Casandra Montoro
Summary: This study found evidence of reduced short-term cerebral blood flow (CBF) variability in patients with major depressive disorder (MDD), which may be attributed to neural activity associated with cognitive processing.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Editorial Material
Anesthesiology
Eric L. Vu, Kenneth Brady, Charles W. Hogue
Summary: Growing evidence suggests that deviations of blood pressure from the limits of cerebral blood flow autoregulation can lead to complications in patients with neurological injury or undergoing cardiac surgery. Maintaining mean arterial pressure above the lower limit of cerebral autoregulation during cardiopulmonary bypass may reduce postoperative delirium and improve memory one month after surgery. Continuous measurement of blood pressure using a virtual patient monitoring platform offers potential for bringing this application to clinical practice.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Medicine, General & Internal
Sam-Yeol Ha, Yeonah Kang, Ho-Joon Lee, Moonjung Hwang, Jiyeon Baik, Seongho Park
Summary: In this study, we compared the quantification of blood flow velocity using non-contrast 4D flow MRI and transcranial Doppler ultrasound (TCD). We found a strong correlation between intracranial velocity measurements obtained by both modalities. Mean velocities acquired with 4D flow MRI were slightly lower compared to TCD, but 4D flow MRI offers the advantage of three-dimensional blood flow visualization.
Meeting Abstract
Clinical Neurology
A. Dagal, I. Lesnik, N. Bentov, J. Dong, Q. Qiu, K. Hayes, D. Gordon
Article
Orthopedics
Robert V. O'Toole, Manjari Joshi, Anthony R. Carlini, Robert A. Sikorski, Armagan Dagal, Clinton K. Murray, Michael J. Weaver, Ebrahim Paryavi, Alec C. Stall, Daniel O. Scharfstein, Julie Agel, Mary Zadnik, Michael J. Bosse, Renan C. Castillo
JOURNAL OF ORTHOPAEDIC TRAUMA
(2017)
Article
Anesthesiology
Michael G. Holmes, Armagan Dagal, Bryan A. Feinstein, Aaron M. Joffe
ANESTHESIA AND ANALGESIA
(2018)
Article
Surgery
Sara Khor, Danielle Lavallee, Amy M. Cizik, Carlo Bellabarba, Jens R. Chapman, Christopher R. Howe, Dawei Lu, A. Alex Mohit, Rod J. Oskouian, Jeffrey R. Roh, Neal Shonnard, Armagan Dagal, David R. Flum
Article
Clinical Neurology
Armagan Dagal, Carlo Bellabarba, Richard Bransford, Fangyi Zhang, Randall M. Chesnut, Grant E. O'Keefe, David R. Wright, Timothy H. Dellit, Ian Painter, Michael J. Souter
Article
Clinical Neurology
Christina W. Cheng, Amy M. Cizik, Armagan H. C. Dagal, Larissa Lewis, John Lynch, Carlo Bellabarba, Richard J. Bransford, Haitao Zhou
Article
Clinical Neurology
Daniel A. Carr, Rajiv Saigal, Fangyi Zhang, Richard J. Bransford, Carlo Bellabarba, Armagan Dagal
NEUROSURGICAL FOCUS
(2019)
Article
Clinical Neurology
Sara Khor, Danielle C. Lavallee, Amy M. Cizik, Carlo Bellabarba, Armagan Dagal, Robert A. Hart, Christopher R. Howe, R. Dean Martz, Neal Shonnard, David R. Flum
Review
Anesthesiology
Ireana C. Ng, Christopher Barnes, Subarna Biswas, David Wright, Arman Dagal
Summary: The timing to resume or initiate anticoagulation therapy following traumatic brain injury is controversial, and individual evaluation is needed to determine when to start anticoagulation. The use of anticoagulants in elderly patients increases the risk of rebleeding, making the decision on when to restart anticoagulation more complex.
CURRENT OPINION IN ANESTHESIOLOGY
(2022)
Article
Critical Care Medicine
Paul Bhalla, Stuart Solomon, Ray Zhang, Cordelie E. Witt, Arman Dagal, Aaron M. Joffe
Summary: A retrospective study comparing serratus anterior plane block (SAPB) and neuraxial block in critically injured adults with multiple rib fractures showed no significant difference in efficacy between the two approaches for pain relief and improved breathing, although the sample size was too small to draw definitive conclusions. Further research with prospective comparative trials is needed to confirm these findings.
TRAUMA SURGERY & ACUTE CARE OPEN
(2021)
Meeting Abstract
Medicine, General & Internal
K. T. Patterson, M. M. Cook, J. Barber, V. N. O'Reilly-Shah, A. H. Dagal, C. Fong, H. Weaver, R. Saigal
JOURNAL OF INVESTIGATIVE MEDICINE
(2021)
Meeting Abstract
Medicine, General & Internal
M. M. Cook, K. T. Patterson, J. Barber, V. N. O'Reilly-Shah, A. H. Dagal, C. Fong, H. Weaver, R. Saigal
JOURNAL OF INVESTIGATIVE MEDICINE
(2021)
Review
Emergency Medicine
Burak Katipoglu, Arman Dagal, Semih Korkut, Abdullah Osman Kocak
EURASIAN JOURNAL OF EMERGENCY MEDICINE
(2020)
Meeting Abstract
Clinical Neurology
Daniel A. Carr, Rajiv Saigal, Armagan Dagal
Article
Anesthesiology
Jacob E. Sunshine, Armagan Dagal, Stephen P. Burns, Richard J. Bransford, Fangyi Zhang, Shu-Fang Newman, Bala G. Nair, Sam R. Sharar
ANESTHESIA AND ANALGESIA
(2017)
