Article
Geriatrics & Gerontology
Darren Hight, David P. Obert, Stephan Kratzer, Gerhard Schneider, Pablo Sepulveda, Jamie Sleigh, Paul S. Garcia, Matthias Kreuzer
Summary: This article investigates the influence of age on the processed EEG information, specifically the permutation entropy (PeEn). The study shows that age affects the PeEn results, indicating the importance of considering age when using PeEn for monitoring patient EEG.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Computer Science, Artificial Intelligence
Xiqiang Huang, Jin Liu, Yinqi Yang, Binglin Yuan, Gazmir Gjoni, Wang Jianxing
Summary: Anesthesia is a crucial measure in healthcare but carries risks. Common clinical indicators are not reliable in estimating anesthesia depth due to variations in patient conditions and medications. This paper proposes an intelligent detection method based on EEG signals and the Transformer framework to predict anesthesia depth. The algorithm achieved a high prediction probability of 85.32% in validation on a sevoflurane anesthesia dataset.
NEURAL COMPUTING & APPLICATIONS
(2023)
Article
Anesthesiology
Stephanie S. Schueler, Christian L. Petersen, Nicholas C. West, J. Mark Ansermino, Richard N. Merchant, Matthias Gorges
Summary: Ketamine was found to increase depth-of-hypnosis index values consistently across three EEG monitoring algorithms, likely due to an increase in power in the beta and gamma bands. However, there were no lasting differences reported in depth-of-hypnosis between the three compared indices.
JOURNAL OF CLINICAL MONITORING AND COMPUTING
(2021)
Article
Anesthesiology
Melody H. Y. Long, Evangeline H. L. Lim, Gustavo A. Balanza, John C. Jr Jr Allen, Patrick L. Purdon, Choon Looi Bong
Summary: The study aimed to determine if EEG-guided anesthesia would result in lower sevoflurane requirements and improved emergence characteristics in children undergoing general anesthesia. The results showed that EEG-guided anesthesia could reduce sevoflurane requirements, decrease the incidence of burst suppression, and maintain similar emergence characteristics. EEG monitoring allows real-time visualization of brain responses and provides a clearer understanding of varying sevoflurane requirements in children of different ages.
JOURNAL OF CLINICAL ANESTHESIA
(2022)
Article
Engineering, Biomedical
Yi-Feng Chen, Shou-Zen Fan, Maysam F. Abbod, Jiann-Shing Shieh, Mingming Zhang
Summary: The proposed EEGV-derived parameters show significant differences in discriminating between awake and anesthesia stages, with improved AUC and correlation coefficient on average compared to conventional EEG features, enhancing detection accuracy of unconscious state and tracking the level of consciousness. EEGV analysis provides a new perspective in quantifying EEG and its parameters show promise for monitoring DOA in clinical settings.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Geriatrics & Gerontology
Susanne Koch, Benjamin Blankertz, Victoria Windmann, Claudia Spies, Finn M. Radtke, Vera Roehr
Summary: This study aimed to determine whether the choice of anesthetic agent affects the risk of postoperative delirium (POD) and if this risk is correlated with the duration of intraoperative burst suppression activity. Through analysis of 1277 patients over 60 years old undergoing general anesthesia, it was found that the risk of POD was higher in patients receiving propofol anesthesia, despite shorter burst suppression duration compared to desflurane anesthesia.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Anesthesiology
Sarah L. Eagleman, Caitlin M. Drover, Xi Li, M. Bruce MacIver, David R. Drover
Summary: The study compares the performance of three processed EEG monitors using pre-recorded EEG signals from older surgical patients. The monitors showed significantly different indices and high effect sizes between comparisons pre-med to after loss of responsiveness (LOR) and before/after LOR. Both PSI and BIS monitors were best at detecting suppressed periods.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Article
Engineering, Biomedical
Manuel A. Francisco-Vicencio, Fernando Gongora-Rivera, Xochitl Ortiz-Jimenez, Dulce Martinez-Peon
Summary: Different cognitive models have been created to understand and rehabilitate attention. This study focuses on sustained attention and uses effective connectivity analysis to uncover the dynamics between brain regions. The findings show dominant connections at specific frequencies and present a low-cost tool for assessing cognitive processes and monitoring attention in real-time rehabilitation and educational settings.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2022)
Article
Anesthesiology
Odmara L. Barreto Chang, Matthias Kreuzer, Danielle F. Morgen, Katherine L. Possin, Paul S. Garcia
Summary: This study found that ketamine administration was associated with increased power in the moderate frequency range of the EEG, but this effect was only observed in cognitively normal patients. Patients with cognitive impairment at baseline did not show significant changes in EEG characteristics after receiving ketamine. However, impaired patients who received ketamine had a significantly higher incidence of postoperative delirium. In cognitively normal patients, the incidence of postoperative delirium was not significantly associated with ketamine administration.
ANESTHESIA AND ANALGESIA
(2022)
Article
Computer Science, Interdisciplinary Applications
Michele Schiavo, Fabrizio Padula, Nicola Latronico, Massimiliano Paltenghi, Antonio Visioli
Summary: This study aims to design a PID-based control system for regulating the depth of hypnosis in total intravenous anesthesia and takes into account the clinical practice. The experimental results demonstrate that the control system can achieve adequate anesthesia without manual intervention from the anesthesiologist.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Anesthesiology
Beatrijs I. Valk, Douglas J. Eleveld, Peter Meyer, Sascha Meier, Izaak den Daas, Kai van Amsterdam, Jason A. Campagna, Steven P. Sweeney, Anthony R. Absalom, Michel M. R. F. Struys
Summary: The study explored the effect of involuntary muscle movements on the pharmacokinetic-pharmacodynamic model of the GABA(A) receptor agonist ABP-700, finding that the BIS model includes an effect-site for BIS suppression and a secondary effect-site related to involuntary muscle movements. The MOAA/S model did not demonstrate excitatory effects in relation to involuntary muscle movements.
Article
Anesthesiology
Sager Nawafleh, Ahmad Alrawashdeh, Omar Ababneh, Morad Bani-Hani, Zaid Al Modanat, Diab Bani Hani, Adel Bataineh, Faisal Al-Salameh, Sajeda Abuzaid, Omer Yasser, Khaled Khairallah
Summary: This study evaluated the practice and attitudes of Jordanian anesthesiologists towards depth of anesthesia (DoA) monitoring and estimated the occurrence of intraoperative awareness among them. The results showed that while most anesthesiologists believe in the effectiveness of DoA monitors in preventing intraoperative awareness, their knowledge and usage of the technology is inadequate.
BMC ANESTHESIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Tamara Timic Stamenic, Slobodan M. Todorovic
Summary: General anesthetics act by modulating synaptic inhibition or excitation, and can affect various proteins, receptors, and channels. The role of T-type calcium channels in the thalamus is of particular interest in sleep and anesthesia. Studies suggest that the Ca(V)3.1 channels contribute to anesthetic-induced thalamocortical oscillations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Geriatrics & Gerontology
Daniela Biggs, Gonzalo Boncompte, Juan C. C. Pedemonte, Carlos Fuentes, Luis I. I. Cortinez
Summary: There are age-related biases in EEG measures of anesthesia hypnosis in elderly patients, and these biases should be taken into consideration when interpreting and designing EEG monitors for clinical settings. Permutation entropy (PE) shows promise as an age-independent measure of hypnotic depth for future monitor development.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Medicine, General & Internal
Chiara Grasso, Vanessa Marchesini, Nicola Disma
Summary: Research on safe anaesthesia management in children has shifted from focusing on the neurotoxic effects to prevention of critical events and maintaining peri-anaesthetic haemodynamic stability to ensure favorable neurological outcomes. Neuro-monitoring can guide anaesthesia providers in delivering optimal drugs dosages and correcting underlying conditions that can negatively affect neurological outcomes.
JOURNAL OF CLINICAL MEDICINE
(2021)