期刊
CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY
卷 13, 期 5, 页码 569-576出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/ACI.0b013e328364ec92
关键词
conjunctiva; cornea; dry eye disease; in-vivo confocal microscopy; ocular allergy
Purpose of reviewTo summarize recent studies on in-vivo confocal microscopy (IVCM) findings in ocular allergy and dry eye disease (DED), highlighting the role of IVCM in the advancement of knowledge of these diseases.Recent findingsIVCM provided new data on ocular surface changes in both ocular allergy and DED. Corneal and conjunctival epithelial and inflammatory cells, corneal nerves, and Meibomian glands showed peculiar patterns of abnormalities, not easily discernable with current clinical exams in these two diseases and their subtypes. At present, small sample size of researches, and poor standardization and evidence of image analysis and interpretation are the most challenging issues.SummaryOcular allergy and DED are common and increasing healthcare problems, and need better understanding of pathogenesis and natural history, more reliable endpoints, and more tailored diagnostic and therapeutic approaches. IVCM allows quick, noninvasive, steady-state respectful examination of the ocular surface at cellular level to be performed and has potential to be used in the future as a biomarker and to contribute to optimize the tailored management of these diseases.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据