The potential use of tyrosine kinase inhibitors in severe asthma

In VivoRole of Platelet-Derived Growth Factor–BB in Airway Smooth Muscle Proliferation in Mouse Lung

(2011) Jeremy A. Hirota et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterization of syk expression in human lung mast cells: relationship with function

(2011) S. Havard et al.   CLINICAL AND EXPERIMENTAL ALLERGY

CCL20/CCR6 Feedback Exaggerates Epidermal Growth Factor Receptor-Dependent MUC5AC Mucin Production in Human Airway Epithelial (NCI-H292) Cells

(2011) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Modulation of Innate and Adaptive Immune Responses by Tofacitinib (CP-690,550)

(2011) Kamran Ghoreschi et al.   JOURNAL OF IMMUNOLOGY

Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma

(2010) Timothy D. Le Cras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NGF/TrkA-mediated Kidins220/ARMS signaling activated in the allergic airway challenge in mice

(2010) Xiuqin Ni et al.   ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY

TH17 Cells in Asthma and COPD

(2010) John F. Alcorn et al.   Annual Review of Physiology

Effects of a Janus kinase inhibitor, pyridone 6, on airway responses in a murine model of asthma

(2010) Yuko Matsunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Induction of insulin-like growth factor-I by interleukin-17F in bronchial epithelial cells

(2010) M. Kawaguchi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

A new look at the pathogenesis of asthma

(2010) Stephen T. Holgate et al.   CLINICAL SCIENCE

Allergen-Induced Coexpression of bFGF and TGF-β1 by Macrophages in a Mouse Model of Airway Remodeling: bFGF Induces Macrophage TGF-β1 Expression in vitro

(2010) Hye Young Yum et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Analyses of asthma severity phenotypes and inflammatory proteins in subjects stratified by sputum granulocytes

(2010) Annette T. Hastie et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma

(2010) Jean Bousquet et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Distinct Roles of Vascular Endothelial Growth Factor Receptor-1- and Receptor-2-Mediated Signaling in T Cell Priming and Th17 Polarization to Lipopolysaccharide-Containing Allergens in the Lung

(2010) Y.-S. Kim et al.   JOURNAL OF IMMUNOLOGY

The indication and effectiveness of low-dose erythromycin therapy in pediatric patients with bronchial asthma*

(2010) Seigo Korematsu et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Involvement of Src family kinase activation in angiotensin II-induced hyperresponsiveness of rat bronchial smooth muscle

(2010) Hiroyasu Sakai et al.   PEPTIDES

Targeting abnormal airway vascularity as a therapeutical strategy in asthma

(2010) Hee Sun PARK et al.   RESPIROLOGY

Advances in the understanding of pathogenesis, and diagnostics and therapeutics for feline allergic asthma

(2010) Carol R. Reinero   VETERINARY JOURNAL

Role of IL-23 and Th17 Cells in Airway Inflammation in Asthma

(2010) Hiroshi Nakajima et al.   Immune Network

Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics

(2009) M. Humbert et al.   ALLERGY

Role of Stem Cell Factor and Bone Marrow-Derived Fibroblasts in Airway Remodeling

(2009) Vladislav A. Dolgachev et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of Insulin-like Growth Factor Binding Protein-3 in Allergic Airway Remodeling

(2009) Kristen L. Veraldi et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Human airway smooth muscle promotes eosinophil differentiation

(2009) A. I. Fanat et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Airway smooth muscle thickness in asthma is related to severity but not duration of asthma

(2009) A. L. James et al.   EUROPEAN RESPIRATORY JOURNAL

Association of VEGF polymorphisms with childhood asthma, lung function and airway responsiveness

(2009) S. Sharma et al.   EUROPEAN RESPIRATORY JOURNAL

Vascular Endothelial Growth Factor Is a Key Mediator in the Development of T Cell Priming and Its Polarization to Type 1 and Type 17 T Helper Cells in the Airways

(2009) Y.-S. Kim et al.   JOURNAL OF IMMUNOLOGY

Stem cell factor and its soluble receptor (c-kit) in serum of asthmatic patients- correlation with disease severity

(2009) Joanna S Makowska et al.   BMC Pulmonary Medicine

Budesonide/formoterol decreases expression of vascular endothelial growth factor (VEGF) and VEGF receptor 1 within airway remodelling in asthma

(2008) Ke Wang et al.   ADVANCES IN THERAPY

Cluster Analysis and Clinical Asthma Phenotypes

(2008) Pranab Haldar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Ca2+ mobilization in desensitization of β-adrenoceptors by platelet-derived growth factor in airway smooth muscle

(2008) Tadasuke Ikenouchi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia

(2008) Elizabeth Kudlacz et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma

(2008) Nandini Krishnamoorthy et al.   NATURE MEDICINE