Article
Chemistry, Multidisciplinary
Xinyu Wang, Shengnan Li, Ping Chen, Fengxiang Li, Xiaomin Hu, Tao Hua
Summary: Photocatalysis is studied for its potential to reduce chemical reagent use and energy consumption, while membrane technology combined with microbial, electrochemical, and catalytic processes can help address micro-pollutants and membrane fouling. However, high operating costs limit the practical applications of these technologies.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Physical
Daniel Tuikhang Koren, Rajan Shrivastava, Shumaila Iqbal Siddiqui, Subhendu Ghosh
Summary: Calmodulin (CaM) is a key signaling protein that regulates mitochondrial Ca2+ homeostasis and signaling by modulating the properties of voltage-dependent anion channel 1 (VDAC1), an abundant protein in the outer mitochondrial membrane (OMM). Experimental findings demonstrate that CaM reduces VDAC1's conductivity, modulates its gating and permeability properties, and may bind to VDAC1. Theoretical analysis suggests that the interaction between CaM and VDAC1 is nonlinear. It is proposed that CaM interacts with VDAC1's outer-loop region and regulates its gating properties. These findings highlight the importance of VDAC1-CaM interaction in ion and metabolite transport through the OMM and regulation of mitochondrial Ca2+ signaling.
JOURNAL OF PHYSICAL CHEMISTRY B
(2022)
Article
Chemistry, Physical
T. Daniel Tuikhang Koren, Rajan Shrivastava, Shumaila Iqbal Siddiqui, Subhendu Ghosh
Summary: Calmodulin (CaM) is a signaling protein that plays a crucial role in mitochondrial Ca2+ homeostasis and signaling as well as modulating the properties of the mitochondrial membrane. The study suggests that voltage-dependent anion channel 1 (VDAC1) could be a target for CaM's action. By reducing VDAC1's conductivity and modulating its gating and permeability properties, CaM may have a significant impact on mitochondrial Ca2+ signaling mechanism. Spectrofluorimetric analysis also indicates the possibility of binding between CaM and VDAC1. The findings suggest that the interaction between VDAC1 and CaM could regulate the transport of ions and metabolites through the outer mitochondrial membrane (OMM) and the mitochondrial Ca2+ signaling mechanism.
JOURNAL OF PHYSICAL CHEMISTRY B
(2022)
Article
Chemistry, Medicinal
Qiufeng Wei, Jing Chen, Fei Xiao, Youbing Tu, Yu Zhong, Yubo Xie
Summary: High concentrations of dexmedetomidine have potential toxic effects on fetal rat hippocampal neurons, leading to neuronal apoptosis.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Review
Physiology
Jannis Koerner, Angelika Lampert
Summary: This article systematically reviews the electrophysiological data of human and rodent dorsal root ganglia neurons (DRGs), revealing differences between species and emphasizing the need for more studies on human sensory neurons.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
(2022)
Review
Chemistry, Physical
Sahng Hyuck Woo, So Young Lee, Young-Gi Yoon, Arnaud Rigacci, Jung-Je Woo, Christian Beauger, Hyoung-Juhn Kim
Summary: The incorporation of nanoclays into polymer matrixes improves the performance of proton exchange membranes (PEMs) in proton exchange membrane fuel cells (PEMFCs), especially at high temperatures and low relative humidity (RH). Nanoclays also enhance the mechanical properties and reduce the cost of composite membranes.
JOURNAL OF POWER SOURCES
(2022)
Article
Neurosciences
Patricia Perez-Garcia, Ricardo Pardillo-Diaz, Noelia Geribaldi-Doldan, Ricardo Gomez-Oliva, Samuel Dominguez-Garcia, Carmen Castro, Pedro Nunez-Abades, Livia Carrascal
Summary: Understanding the development of specialized neural circuits in adult mammals requires studying the changes in neuronal membrane properties and circuits during postnatal maturation. Research on layer V pyramidal neurons in the rat primary motor cortex showed that certain parameters are established at birth, while other properties continue to develop until adulthood. These modifications lead to a decrease in neuronal excitability and an increase in working range, providing more sensitive and accurate responses in young adult neurons.
FRONTIERS IN MOLECULAR NEUROSCIENCE
(2021)
Article
Engineering, Environmental
Shubham Rahul Sawant, Sarita Kalla, Z. V. P. Murthy
Summary: The use of nanomaterials to modify membrane distillation membranes enhances their performance by avoiding wetting and fouling. This study critically analyzes the advancement made in the use of multi-walled carbon nanotubes and sodium alginate for PVDF membrane modification and further analyzes the developed membrane for water desalination through the direct contact membrane distillation process.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Engineering, Chemical
Jun Pan, Fangli Zhang, Zhaohui Wang, Shi-Peng Sun, Zhaoliang Cui, Wanqin Jin, Omar Bamaga, Hani. Abulkhair, Mohammed Albeirutty, Enrico Drioli
Summary: The composite hydrophobic PFPE/PVDF membranes show promising anti-fouling and anti-wetting performance, making them highly suitable for membrane distillation and membrane crystallization applications.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Engineering, Environmental
Sharjeel Waqas, Muhammad Roil Bilad, Aqsha Aqsha, Noorfidza Yub Harun, Muhammad Ayoub, Mohd Dzul Hakim Wirzal, Juhana Jaafar, Sri Mulyati, Muthia Elma
Summary: This study compares the biological and hydraulic performances of PVDF and PSF membranes in a rotating biological contactor system. Results show that the steady-state permeabilities of the membranes in MRBC are significantly higher than external filtration, with MRBC consuming only one-fourth of the energy of a traditional membrane bioreactor.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Environmental Sciences
Lanhe Zhang, Lu Wang, Yuning Zhang, Da Wang, Jingbo Guo, Mingshuang Zhang, Yiran Li
Summary: The electrode ultrafiltration membrane bioreactor (EMBR) showed better performance and membrane fouling characteristics in treating cosmetics wastewater, with increased COD removal efficiency and reduced transmembrane pressure compared to the conventional ultrafiltration membrane bioreactor (UMBR). The electrode ultrafiltration membrane had a higher energy barrier with pollutants, contributing to its strong anti-fouling property.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biotechnology & Applied Microbiology
Ying Wang, Juan Shen, Fanqiang Meng, Zhaoxin Lu, Fengxia Lv, Libang Zhou, Haizhen Zhao
Summary: The study aimed to investigate the antibacterial mechanism of MLGG by studying its effects on cell membranes. The changes in cell membrane properties of B. cereus exposed to different concentrations of MLGG were evaluated. It was found that low concentrations of MLGG prolonged the lag phase of B. cereus cells, while high concentrations resulted in a reduction in bacterial populations. MLGG treatment caused membrane depolarization and an increase in membrane fluidity, with changes observed in fatty acid compositions. Resistance tests indicated the effectiveness of MLGG as a bacteriostatic agent.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Environmental Sciences
Kai Li, Weihua Xu, Gang Wen, Zhipeng Zhou, Min Han, Shujia Zhang, Tinglin Huang
Summary: This study systematically investigated the effects of long-term ozone exposure on the properties and performance of a polyvinylidene fluoride (PVDF) ultrafiltration (UF) membrane reinforced by a polyethylene terephthalate (PET) layer. The study found that ozone exposure resulted in an increase in pore size and a decrease in surface hydrophilicity of the membrane, as well as a decrease in membrane tensile strength. Furthermore, long-term ozone exposure led to an increase in membrane permeability, a decrease in retention ability, and an increase in organic fouling propensity.
Article
Materials Science, Multidisciplinary
Daehun Kim, Ahrumi Park, Yunyoung Choi, Hyejeong Seong, Sung Ju Shin, Young Hoon Cho, Youngmin Yoo
Summary: An antifouling Janus membrane for membrane distillation was fabricated using a photoinitiated chemical vapor deposition process. The membrane exhibited a maintained porous structure and different properties on each side due to the asymmetric deposition of a hydrophilic polymer. The Janus membrane showed superior oil antifouling properties and confirmed stability after MD testing.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Engineering, Chemical
Jun Ma, Hang Xu, Anqi Wang, Ao Wang, Li Gao, Mingmei Ding
Summary: Membrane distillation is a promising membrane technology for producing freshwater from high concentration brines. A comprehensive machine learning workflow was developed to predict its performance and extract insights on important factors. The results showed the significant contributions of temperature difference, water contact angle, and membrane size to the system performance.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Dermatology
Katarzyna Rosicka, Barbara Mierzejewska-Krzyzowska, Wlodzimierz Mrowczynski
Summary: In a pioneering study, skin stiffness was measured using MyotonPRO in 30 healthy young women at various locations. Results showed no significant difference in stiffness values between L-shaped probes, but significant differences with regular and disc attachment probes. MyotonPRO proved to be a reliable device for skin stiffness assessment.
SKIN RESEARCH AND TECHNOLOGY
(2021)
Article
Physiology
Ian C. Smith, Franziska Onasch, Katarzyna Krysciak, Jan Celichowski, Walter Herzog
Summary: Boost and sag in human muscle are diminished in repeated contractions with short rest periods, but re-established or enhanced with long rest periods. This sensitivity to contractile history may have applications in strength and power sports.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Biochemical Research Methods
Rositsa Raikova, Vessela Krasteva, Piotr Krutki, Hanna Drzymala-Celichowska, Katarzyna Krysciak, Jan Celichowski
Summary: The synchronization of motor units (MUs) increases fluctuations in muscle force, with higher synchronization resulting in increased force variability while mean force levels remain nearly unchanged and frequency of force oscillations decreases. Fast MUs show higher absolute force variability compared to slow MUs, but synchronized slow MUs exhibit the highest relative increase in force variability, indicating their significant contribution to muscle tremor during weak contractions.
PLOS COMPUTATIONAL BIOLOGY
(2021)
Article
Physiology
Dawid Lochynski, Dominik Kaczmarek, Marcin Grzeskowiak, Joanna Majerczak, Tomasz Podgorski, Jan Celichowski
Summary: The study found that after short-term resistance training, the twitch contraction time and twitch:tetanus force ratio of FR MUs decreased, while PTP capacity remained unchanged; in contrast, FF MUs showed enhanced PTP ability and lower fatigability.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Cell Biology
Kamil Ziarniak, Monika Dudek, Julia Matuszewska, Lukasz Bijoch, Marek Skrzypski, Jan Celichowski, Joanna H. Sliwowska
Summary: ADR plays a role in metabolism regulation, with its alterations in obesity and diabetes. Exercise can increase ADR concentrations, but its distribution in the brain remains unclear. This study found that 2 weeks of forced moderate intensity locomotor training induced a stress response with increased corticosterone levels, but did not affect the number of ADR-ir cells in the brain.
Article
Physiology
Piotr Krutki, Wlodzimierz Mrowczynski, Jan Celichowski, Marcin Baczyk
Summary: This study provides new insights into neuronal plasticity following repeated mechanical loading. Through electrophysiological experiments on rat lumbar motoneurons, we demonstrate that low-volume whole body vibration applied systematically for 5 weeks enhances synaptic excitation from primary muscle afferents. The adaptive changes are characterized by higher amplitudes and shorter rise times of monosynaptic EPSPs in the vibrated group compared to the control.
JOURNAL OF APPLIED PHYSIOLOGY
(2022)
Article
Dermatology
Katarzyna Rosicka, Barbara Mierzejewska-Krzyzowska, Wlodzimierz Mrowczynski
Summary: This study evaluated the suitability of MyotonPRO for assessing skin biomechanical and viscoelastic parameters, aiming to establish reference values at various skin locations. While differences were found among parameters measured in different areas, there were no significant differences when using different probes in the same area. Strong correlations between some studied parameters were observed across all investigated skin areas.
SKIN RESEARCH AND TECHNOLOGY
(2022)
Article
Nutrition & Dietetics
Dawid Lochynski, Maciej Pawlak, Inge Everaert, Tomasz Podgorski, Magdalena Gartych, Anna-Maria Borucka, Jan Celichowski, Wim Derave, Dominik Kaczmarek
Summary: The study found that long-term carnosine supplementation can maintain the force of FF muscle units at a higher level during rapid decline and result in less rapid force decline in both FF and FR muscle units. Carnosine supplementation did not change muscle antioxidant potential, mortality rate, or muscle mass with aging.
Article
Neurosciences
Hanna Drzymala-Celichowska, Jan Celichowski, Marcin Baczyk, Piotr Krutki
Summary: This study found that the differences in motor performance between male and female rats are mainly due to differences in muscle mass, the proportion of muscle fiber types, and motor unit contractile properties, while the electrophysiological activity of motoneurons is similar between the sexes.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Piotr Krutki, Hanna Drzymala-Celichowska, Marcin Baczyk, Magdalena Piotr, Jan Celichowski
Summary: Male and female rats have differences in muscle fibre composition, motor unit contractile properties, and muscle spindle density, but their motoneurons' intrinsic properties are similar. This study aimed to investigate whether sex differences in body mass and muscle force influence the proprioceptive input from muscle spindles to motoneurons. The results showed that there were no differences in latency, but males had a higher amplitude of EPSP compared to females. The observed sex differences may be related to mechanical loading or hormonal differences.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Norbert Grzelak, Piotr Krutki, Marcin Baczyk, Dominik Kaczmarek, Wlodzimierz Mrowczynski
Summary: The purpose of this study was to investigate the effect of altered BDNF concentrations on the electrophysiological properties of spinal MNs. The study found that changes in muscle concentrations of BDNF and GDNF may be critical factors that modify the excitability of spinal MNs after intense physical activity.
SCIENTIFIC REPORTS
(2023)
Review
Physiology
Marcin Baczyk, Piotr Krutki, Daniel Zytnicki
Summary: ALS is a fatal neurodegenerative disease characterized by progressive loss of motoneurons. Research suggests that interventions targeting intrinsic excitability or synaptic excitation in presymptomatic ALS mice can reduce disease markers in motoneurons and delay neuro-muscular junction denervation. Anodal trans-spinal direct current stimulation (tsDCS) has been shown to enhance motoneuron excitability and synaptic inputs in ALS mice, indicating its potential as a complementary method in managing ALS patients.
PHYSIOLOGICAL REPORTS
(2021)
