期刊
CURRENT NANOSCIENCE
卷 7, 期 2, 页码 178-182出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/157341311794653578
关键词
Biosensor; functionalization; nanostructured porous silicon; electrical detection
类别
资金
- Comunidad de Madrid (Spain)
- Ministerio de Ciencia e Innovacion (MICINN) [FUNCOAT-CSD2008-00023]
Nanostructured porous silicon (nanoPS) basically consists in a network of silicon nanocrystals with high specific surface. Its intrinsic high surface reactivity makes nanoPS a very suitable material for the development of biosensors. In this work, the surface of nanoPS was functionalized by the use of (3-aminopropyl)triethoxysilane solutions in toluene. Escherichia coli (E. coli) antibodies were subsequently immobilized on the functionalized surfaces. Finally, fragments of this bacterium, which are specifically recognized by the antibodies, were immobilized. Moreover, devices with a metal/nanoPS/semiconductor/ metal structure were fabricated aiming at the electrical biosensing of E. Coli bacterium. The experimental results showed a strong variation of the current as a function of the presence/absence of bacterium E. Coli and surface concentration.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据