期刊
CURRENT MEDICINAL CHEMISTRY
卷 20, 期 37, 页码 4758-4776出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/09298673113209990159
关键词
Cancer; inflammation; olive oil; oxidative stress; phenols
资金
- Spanish Ministerio de Ciencia e Innovacion [AGL 2008-02475, AGL 2011-26949]
- Junta de Andalucia
- Postgraduate National Program of FPU fellowship
- Spanish Ministerio de Educacion
Olive oil (OO), the main fatty component of the Mediterranean diet, exhibits numerous biological functions which are beneficial for the state of health. In addition to monounsaturated fatty acid (MUFA) evidences have accumulated on the favorable properties of its minor though highly bioactive components, particularly the phenolic compounds, which have shown a broad spectrum of bioactive properties, including antioxidant and anti-inflammatory effects both associated with the origin of the main chronic diseases. Additional studies have demonstrated that the health effects of olive oil polyphenols have been also associated with their, neuroprotective, antiaging and antiatherogenic effects. On the other hand, because of their ability to modulate cell death, olive polyphenols have been proposed as chemopreventive and therapeutic agents. Thus, the purpose of this article is to review the chemistry, bioavailability and pharmacokinetic characteristics of OO polyphenols, in addition to provide the reader an up-date of their putative antioxidant, anti-inflammatory and anti-cancer activities as well as the plausible action mechanisms involved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据