Article
Public, Environmental & Occupational Health
Gabriella Yazbeck, Diana Malaeb, Hamid Shaaban, Abir Sarray El Dine, Souheil Hallit, Rabih Hallit
Summary: This study aimed to assess the rate of unidentified IBS among Lebanese adults and investigate the role of socio-demographic factors, anxiety, depression, insomnia, and eating attitudes on IBS diagnosis. A cross-sectional study was conducted using a self-reporting questionnaire distributed via social media. The study found that higher psychological distress and insomnia severity were significantly associated with higher odds of having possible unidentified IBS.
Review
Medicine, General & Internal
Mihaela Fadgyas Stanculete, Abdulrahman Ismaiel, Stefan-Lucian Popa, Octavia Oana Capatina
Summary: Irritable bowel syndrome (IBS) is a disorder characterized by altered gut-brain interaction and dysfunction of the brain-gut-microbiota axis. Prior studies have shown significant impairments in the health-related quality of life of patients with IBS. Resilience, as a psychosocial ability, plays a crucial role in promoting health and enhancing stress response.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Vivek C. Goodoory, Cho E. Ng, Christopher J. Black, Alexander C. Ford
Summary: This study compared the characteristics of individuals with irritable bowel syndrome (IBS) reporting faecal incontinence (FI) with those who do not report FI. The results showed that individuals with FI were older, more likely to have IBS-D, had lower education levels and incomes, reported more urgency and more severe IBS and psychological symptoms, had lower quality of life scores, and higher healthcare costs.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Review
Psychiatry
Shefaly Shorey, Alla Demutska, Valerie Chan, Kewin Tien Ho Siah
Summary: This study synthesized 17 qualitative studies on the experiences of adults living with IBS, highlighting the negative impacts on physical, psychological, and social aspects, and the need for future research on diverse geographical locations. Furthermore, interventions such as technology-based support, trained peer volunteers, mindfulness, and cognitive behavioural therapy are essential for supporting IBS patients. Collaboration among stakeholders is crucial for developing standardized tools and materials for accurate testing, diagnosis, assessment, treatment, and management of IBS.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Article
Gastroenterology & Hepatology
Sarah Zaza, John Alverdy
Summary: This article highlights the challenges faced by surgeons when dealing with patients suffering from IBS who present with a defined anatomic abnormality. It emphasizes the importance of a multidisciplinary approach to avoid unnecessary surgery in these patients.
JOURNAL OF GASTROINTESTINAL SURGERY
(2023)
Review
Chemistry, Medicinal
Ewa Dudzinska, Andreas M. Grabrucker, Pawel Kwiatkowski, Robert Sitarz, Monika Sienkiewicz
Summary: Visceral stimuli from the digestive tract are transmitted to the brain via nerves, causing overreaction in the brain of irritable bowel syndrome (IBS) patients. Stress and dysbiosis can lead to inflammation and gastrointestinal hypersensitivity. Treating IBS involves reducing visceral hypersensitivity and regulating the intestinal microbiota.
Review
Nutrition & Dietetics
Claudia Di Rosa, Annamaria Altomare, Vittoria Terrigno, Florencia Carbone, Jan Tack, Michele Cicala, Michele Pier Luca Guarino
Summary: Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habits. The exact cause of IBS is not fully understood, but it is believed to involve a combination of factors such as abnormal gut motility, inflammation, increased intestinal permeability, and sensitivity. Diet and gut microbiota have also been identified as important contributors to IBS. This review examines the effects of dietary components, functional foods, prebiotics, probiotics, and symbiotics on symptoms and gut microbiota in individuals with IBS-C.
Review
Nutrition & Dietetics
Dominika Glabska, Aleksandra Kolota, Katarzyna Lachowicz, Dominika Skolmowska, Malgorzata Stachon, Dominika Guzek
Summary: Inflammatory bowel diseases (IBDs) and irritable bowel syndrome (IBS) are associated with decreased quality of life and mental health problems. Vitamin D supplementation is considered to be effective in improving mental health in affected individuals. Studies have shown a positive effect of vitamin D supplementation on the mental health of IBD and IBS patients, but further research is needed for confirmation.
Review
Health Care Sciences & Services
Hyunjung Kim, Younjae Oh, Sun Ju Chang
Summary: This study systematically reviewed the use of internet-delivered cognitive behavioral therapy in patients with irritable bowel syndrome and evaluated its effects on symptom severity, quality of life, psychological status, and cost-effectiveness.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Medicine, General & Internal
Samira Ait Abdellah, Julien Scanzi, Caroline Gal, Marc Martin, Marc Beck, Veronica Ojetti
Summary: This multicenter study investigated the effects of L. gasseri LA806 supplementation on IBS symptoms and quality of life. The study found that the majority of patients experienced a significant decrease in abdominal pain and improvement in overall IBS symptoms and quality of life after 4 weeks of supplementation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Florian Mourey, Amelie Decherf, Jean-Francois Jeanne, Mathieu Clement-Ziza, Marie-Lise Grisoni, Francois Machuron, Sophie Legrain-Raspaud, Arnaud Bourreille, Pierre Desreumaux
Summary: This study confirmed the efficacy of S. cerevisiae I-3856 in managing gastrointestinal symptoms in IBS-C, particularly in alleviating abdominal pain. The relief of abdominal pain was associated with improved quality of life.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Health Care Sciences & Services
Rosel Sturkenboom, Daniel Keszthelyi, Lloyd Brandts, Zsa Zsa R. M. Weerts, Johanna T. W. Snijkers, Ad A. M. Masclee, Brigitte A. B. Essers
Summary: This study developed an algorithm for calculating utility values using the condition-specific IBS-QoL questionnaire for economic evaluations. The model chosen included the total IBS-QoL score and squared IBS-SSS, demonstrating improved performance.
QUALITY OF LIFE RESEARCH
(2022)
Article
Nutrition & Dietetics
Narges Ghorbani Bavani, Zahra Hajhashemy, Parvane Saneei, Ammar Hassanzadeh Keshteli, Ahmad Esmaillzadeh, Peyman Adibi
Summary: This study found a relationship between meal regularity and the prevalence of irritable bowel syndrome (IBS). Participants with regular meal patterns had a lower risk of developing IBS, particularly women and individuals with normal weight.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Isabella Gigante, Valeria Tutino, Francesco Russo, Valentina De Nunzio, Sergio Coletta, Raffaele Armentano, Alberto Crovace, Maria Gabriella Caruso, Antonella Orlando, Maria Notarnicola
Summary: The study found that a high-fat diet can improve gastrointestinal symptoms and functions in an animal model of IBS by restoring intestinal tissue damage, upregulating CB1 and CB2 receptors, and affecting glucose metabolism and intestinal membrane permeability.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Cell Biology
Karem Awad, Christian Barmeyer, Christian Bojarski, Oliver Nagel, In-Fah M. Lee, Michal R. Schweiger, Joerg-Dieter Schulzke, Roland Buecker
Summary: This study investigated the pathophysiological mechanisms of diarrhea, constipation, and antigen uptake in mixed-type irritable bowel syndrome (IBS-M). The findings showed that in IBS-M, chloride secretion was reduced and antigen permeability was increased, which contributed to a low-grade inflammation in the colon mucosa.