Review of the effect of opioid-related side effects on the undertreatment of moderate to severe chronic non-cancer pain: tapentadol, a step toward a solution?

Efficacy and tolerability of tapentadol immediate release and oxycodone HCl immediate release in patients awaiting primary joint replacement surgery for end-stage joint disease: A 10-day, phase III, randomized, double-blind, active- and placebo-controlled study

(2009) Craig Hartrick et al.   CLINICAL THERAPEUTICS

A randomized, double-blind, placebo-controlled phase 3 study of the relative efficacy and tolerability of tapentadol IR and oxycodone IR for acute pain

(2009) Stephen Daniels et al.   CURRENT MEDICAL RESEARCH AND OPINION

A randomized, double-blind, phase III study comparing multiple doses of tapentadol IR, oxycodone IR, and placebo for postoperative (bunionectomy) pain

(2009) Stephen E. Daniels et al.   CURRENT MEDICAL RESEARCH AND OPINION

Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study

(2009) Martin Hale et al.   CURRENT MEDICAL RESEARCH AND OPINION

Efficacy, safety, and gastrointestinal tolerability of tapentadol ER in a randomized, double-blind, placebo- and active-controlled phase III study of patients with chronic low back pain

(2009) R. Buynak et al.   JOURNAL OF PAIN

Management of opioid medications in patients with chronic pain and risk of substance misuse

(2009) Seddon R. Savage   Current Psychiatry Reports

What is the Case for Prescribing Long-Acting Opioids Over Short-Acting Opioids for Patients with Chronic Pain? A Critical Review

(2009) Richard L. Rauck   Pain Practice

Single Dose Analgesic Efficacy of Tapentadol in Postsurgical Dental Pain: The Results of a Randomized, Double-Blind, Placebo-Controlled Study

(2008) Regina Kleinert et al.   ANESTHESIA AND ANALGESIA

The efficacy and tolerability of multiple-dose tapentadol immediate release for the relief of acute pain following orthopedic (bunionectomy) surgery

(2008) Jens-Ulrich Stegmann et al.   CURRENT MEDICAL RESEARCH AND OPINION

A randomised controlled trial with prolonged-release oral oxycodone and naloxone to prevent and reverse opioid-induced constipation

(2008) Winfried Meissner et al.   EUROPEAN JOURNAL OF PAIN

Patient assessment of a novel therapeutic approach for the treatment of severe, chronic pain

(2008) J. Nadstawek et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

TRPV1 Receptor in Expression of Opioid-Induced Hyperalgesia

(2008) Anna Vardanyan et al.   JOURNAL OF PAIN

Patient Barriers to Pain Management May Contribute to Poor Pain Control in Rheumatoid Arthritis

(2008) Mary-Ann Fitzcharles et al.   JOURNAL OF PAIN

Methylnaltrexone for Opioid-Induced Constipation in Advanced Illness

(2008) Jay Thomas et al.   NEW ENGLAND JOURNAL OF MEDICINE

Alvimopan, a peripherally acting mu-opioid receptor (PAM-OR) antagonist for the treatment of opioid-induced bowel dysfunction: Results from a randomized, double-blind, placebo-controlled, dose-finding study in subjects taking opioids for chronic non-cancer pain

(2008) Lynn Webster et al.   PAIN

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE

What Percentage of Chronic Nonmalignant Pain Patients Exposed to Chronic Opioid Analgesic Therapy Develop Abuse/Addiction and/or Aberrant Drug-Related Behaviors? A Structured Evidence-Based Review

(2007) David A. Fishbain et al.   PAIN MEDICINE