Nuclear Factor (Erythroid-Derived 2)-Like-2 Factor (Nrf2), a Key Regulator of the Antioxidant Response to Protect Against Atherosclerosis and Nonalcoholic Steatohepatitis
出版年份 2013 全文链接
标题
Nuclear Factor (Erythroid-Derived 2)-Like-2 Factor (Nrf2), a Key Regulator of the Antioxidant Response to Protect Against Atherosclerosis and Nonalcoholic Steatohepatitis
作者
关键词
Nrf2, Oxidative stress, Atherosclerosis, Nonalcoholic steatohepatitis, NASH
出版物
Current Diabetes Reports
Volume 13, Issue 3, Pages 362-371
出版商
Springer Nature
发表日期
2013-03-08
DOI
10.1007/s11892-013-0372-1
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Myeloid Deletion of Nuclear Factor Erythroid 2−Related Factor 2 Increases Atherosclerosis and Liver Injury
- (2012) Alan R. Collins et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage
- (2012) Soo Han Bae et al. Cell Metabolism
- Nonalcoholic Fatty Liver Disease/Steatohepatitis: Epidemiology, Pathogenesis, Clinical Presentation and Treatment
- (2012) Sandra Milic et al. DIGESTIVE DISEASES
- Nuclear factor erythroid 2-like 2 (Nrf2) expression in end-stage liver disease
- (2012) Mateusz Kurzawski et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Functional dissection of Nrf2-dependent phase II genes in vascular inflammation and endotoxic injury using Keap1 siRNA
- (2012) Ji-Hee Kim et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance
- (2012) Akshaya K. Meher et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2 protects against diquat-induced liver and lung injury
- (2012) Kai Connie Wu et al. FREE RADICAL RESEARCH
- Escalating Obesity Rates Pose Health, Budget Threats
- (2012) Rebecca Voelker JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways
- (2012) Shurong Huang et al. JOURNAL OF LIPID RESEARCH
- Disruption of Nrf2 Signaling Impairs Angiogenic Capacity of Endothelial Cells: Implications for Microvascular Aging
- (2012) M. N. Valcarcel-Ares et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha
- (2012) B. N. Chorley et al. NUCLEIC ACIDS RESEARCH
- Effect of Graded Nrf2 Activation on Phase-I and -II Drug Metabolizing Enzymes and Transporters in Mouse Liver
- (2012) Kai Connie Wu et al. PLoS One
- Current strategies to minimize hepatic ischemia–reperfusion injury by targeting reactive oxygen species
- (2012) Hartmut Jaeschke et al. Transplantation Reviews
- Oxidative Stress in Atherosclerosis Development: The Central Role of LDL and Oxidative Burst
- (2012) Ilaria Peluso et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia
- (2011) Zoltan Ungvari et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Age-related changes of Nrf2 and phosphorylated GSK-3β in a mouse model of accelerated aging (SAMP8)
- (2011) Koji Tomobe et al. ARCHIVES OF GERONTOLOGY AND GERIATRICS
- Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis
- (2011) Christopher M. Scull et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Nrf2 Represses FGF21 During Long-Term High-Fat Diet-Induced Obesity in Mice
- (2011) D. V. Chartoumpekis et al. DIABETES
- Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis
- (2011) Stefan Freigang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Sulforaphane attenuates hepatic fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling
- (2011) Chang Joo Oh et al. FREE RADICAL BIOLOGY AND MEDICINE
- Age-Associated Vascular Oxidative Stress, Nrf2 Dysfunction, and NF- B Activation in the Nonhuman Primate Macaca mulatta
- (2011) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The renin-angiotensin system: a link between obesity, inflammation and insulin resistance
- (2011) N. S. Kalupahana et al. Obesity Reviews
- NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection
- (2010) Berenice Barajas et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Protective effects of magnesium lithospermate B against diabetic atherosclerosis via Nrf2-ARE-NQO1 transcriptional pathway
- (2010) Kyu Yeon Hur et al. ATHEROSCLEROSIS
- Signaling Functions of Reactive Oxygen Species
- (2010) Henry Jay Forman et al. BIOCHEMISTRY
- Activation of Protein Kinase C Isoforms and Its Impact on Diabetic Complications
- (2010) Pedro Geraldes et al. CIRCULATION RESEARCH
- Oxidative Stress and Diabetic Complications
- (2010) Ferdinando Giacco et al. CIRCULATION RESEARCH
- Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice
- (2010) Anisha A. Gupte et al. HEPATOLOGY
- Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity
- (2010) Jingbo Pi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
- (2010) Arun J. Sanyal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nitric oxide and oxidative stress in vascular disease
- (2010) Ulrich Förstermann PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice
- (2009) Hirokazu Sugimoto et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Decision Analysis Supports the Paradigm That Indiscriminate Supplementation of Vitamin E Does More Harm than Good
- (2009) Yedidya Dotan et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State
- (2009) Mustafa Zakkar et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Age-Accelerated Atherosclerosis Correlates With Failure to Upregulate Antioxidant Genes
- (2009) Alan R. Collins et al. CIRCULATION RESEARCH
- The Inflamed Liver and Atherosclerosis: A Link Between Histologic Severity of Nonalcoholic Fatty Liver Disease and Increased Cardiovascular Risk
- (2009) Naim Alkhouri et al. DIGESTIVE DISEASES AND SCIENCES
- Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide
- (2009) Soona Shin et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
- (2009) Ethan J. Anderson et al. JOURNAL OF CLINICAL INVESTIGATION
- Molecular mechanisms involved in NAFLD progression
- (2009) Mariano Malaguarnera et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Antioxidants prevent health-promoting effects of physical exercise in humans
- (2009) M. Ristow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-β1 expression
- (2009) Hoo-Kyun Choi et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Why Have Antioxidants Failed in Clinical Trials?
- (2008) Steven R. Steinhubl AMERICAN JOURNAL OF CARDIOLOGY
- Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
- (2008) Timothy R. Koves et al. Cell Metabolism
- Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity
- (2008) T. Yamamoto et al. MOLECULAR AND CELLULAR BIOLOGY
- Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice
- (2008) Thomas E. Sussan et al. PLoS One
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