Review
Toxicology
Maciej Noga, Kamil Jurowski
Summary: Novichok is a group of nerve agents created secretly by the Soviet Union in the later phases of the Cold War. They are highly toxic and designed to be incurable and undetectable. This article provides a general overview of Novichoks, including their physical and chemical properties, synthesis, mechanism of action, and toxicity. It highlights the threat posed by these compounds and encourages further interdisciplinary studies.
ARCHIVES OF TOXICOLOGY
(2022)
Review
Immunology
Linda Abou Chacra, Florence Fenollar, Khoudia Diop
Summary: The vaginal microbiome is an important part of the human microbiome, characterized by unique conditions. Increased diversity in the microbiota can lead to dysbiosis such as bacterial vaginosis, with significant health consequences. Diagnosis and treatment methods are evolving, and research on this topic is becoming increasingly important.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Orthopedics
Giovanni Bonaspetti, Giovanni Dib, Flavio Azzola, Alessia Piovani
Summary: This study reviews the current understanding of patellofemoral osteochondritis dissecans (PF-OCD) and presents a rare case of an adult female patient with progressive multifocal PF-OCD. The available evidence on treatment for PF-OCD is of low quality, based on single case reports or small retrospective case series.
Review
Physics, Applied
Xiangdong Ji, Feng Yuan, Yong Zhao
Summary: There has been significant progress in understanding the origins of proton spin, focusing on first-principles calculations and experimental measurements of total gluon helicity, quark, and gluon orbital angular momenta.
NATURE REVIEWS PHYSICS
(2021)
Review
Public, Environmental & Occupational Health
Sam T. Donta
Summary: The cause of Lyme disease is known, but the etiology of persisting symptoms remains undefined, posing challenges in diagnosis and treatment. Currently, there are no tests available to determine the presence or absence of the infection, complicating the management of Lyme disease.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Biochemistry & Molecular Biology
Adriana Volna, Martin Bartas, Petr Pecinka, Vladimir Spunda, Jiri Cerven
Summary: This paper reviews the current understanding of miRNAs in spring barley, discussing their roles in plant development, homeostasis, and immune processes, and proposing future research directions and unresolved questions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Jose L. Domingo
Summary: The origin of COVID-19 has been a topic of much debate, with some supporting a natural origin while others suggesting a possible unnatural origin. Clear evidence confirming the intermediate host of SARS-CoV-2 is still lacking, and investigations into the origin are crucial in preventing similar future pandemics.
ENVIRONMENTAL RESEARCH
(2021)
Review
Oncology
Nancy Delgado, Anahi Torres
Summary: This review examines the relationship between chronic myeloid leukemia (CML) and COVID-19, including the risk factors, prognosis, and the role of tyrosine kinase inhibitors (TKIs). The findings suggest that CML patients in the chronic phase are not at a higher risk of infection by SARS-CoV-2 than the general population. TKIs may have a therapeutic effect against COVID-19, but further large-scale studies are needed to confirm this.
CURRENT ONCOLOGY REPORTS
(2022)
Review
Multidisciplinary Sciences
Carlos Pilotto Heming, Wanjiru Muriithi, Lucy Wanjiku Macharia, Paulo Niemeyer Filho, Vivaldo Moura-Neto, Veronica Aran
Summary: Acquired resistance during cancer treatment is often caused by ABC transporters, such as P-gp, which export chemotherapeutic molecules and contribute to multidrug resistance. In addition to its role in drug resistance, P-gp may also have other functions and serve as a biomarker in cancer.
Article
Cardiac & Cardiovascular Systems
Yike Zhu, Vinh Dang Do, A. Mark Richards, Roger Foo
Summary: The article discusses the importance of cardiomyocyte dedifferentiation in cardiac regeneration and the challenges in studying it. Despite some genes being proven to promote endogenous CM proliferation and the belief that CM dedifferentiation precedes cell division, there are still knowledge gaps and controversies surrounding the definition of CM dedifferentiation.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
(2021)
Review
Pediatrics
Christopher A. O'Dea, Michael L. Beaven, Andrew C. Wilson, Elizabeth F. Smith, Andrew Maiorana, Shannon J. Simpson
Summary: The long-term cardiopulmonary outcomes of preterm birth during the surfactant era are still unclear. Preterm children often experience respiratory symptoms, especially during exertion. Cardiopulmonary exercise testing can provide insights into the underlying causes of these exertional respiratory symptoms in preterm born children. This review aims to summarize the current knowledge on the use of cardiopulmonary exercise testing to assess children born preterm in the surfactant era.
FRONTIERS IN PEDIATRICS
(2023)
Review
Biochemistry & Molecular Biology
Natalia Harumi Correa Kobayashi, Sarah Viana Farias, Diandra Araujo Luz, Kissila Marvia Machado-Ferraro, Brenda Costa da Conceicao, Cinthia Cristina Menezes da Silveira, Luanna Melo Pereira Fernandes, Sabrina de Carvalho Cartagenes, Vania Maria Moraes Ferreira, Eneas Andrade Fontes-Junior, Cristiane do Socorro Ferraz Maia
Summary: This review examines the toxicological mechanisms and physiological effects on different body systems of co-abusing ketamine and ethanol. It also discusses the potential shared molecular mechanisms that may lead to additional hazardous effects. The review points out the gaps in knowledge in this area and emphasizes the need for further research.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Clinical Neurology
Borros Arneth
Summary: Multiple sclerosis (MS) is a complex autoimmune disorder characterized by neurologic dysfunction that worsens as the disease progresses. This study aimed to examine the role of T cells in MS pathogenesis, revealing significant link between MS and T cell activity. Targeting T cells is a potential strategy for the development of new therapies to manage MS, indicating the influence of effector T cells and regulatory T cells on MS development and progression.
JOURNAL OF NEUROLOGY
(2021)
Article
Engineering, Environmental
Jonn Axsen, Scott Hardman, Alan Jenn
Summary: This article highlights the importance of zero-emissions vehicles (ZEVs) in decarbonizing the transport sector and focuses on the effectiveness and impact of a ZEV sales mandate policy in the long term. It presents an interdisciplinary framework to address the complexity of the policy and summarizes limited evidence on policy effectiveness, efficiency, public acceptability, and transformative potential.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Construction & Building Technology
Patrick Sharpe, Benjamin Jones, Robin Wilson, Christopher Iddon
Summary: This study focuses on natural ventilation as a low energy strategy and the behavior of openings. It introduces an analytical framework to define different types of flow through openings and a Statistical Effective Area Model (SEAM) to evaluate and compare different design approaches. The study also explores the impact of opening structures on ventilation effectiveness and the reduction in discharge coefficient due to temperature differences.
ENERGY AND BUILDINGS
(2021)
Article
Behavioral Sciences
Karen L. Bunday, Roger N. Lemon, James M. Kilner, Marco Davare, Guy A. Orban
Article
Clinical Neurology
Charles R. Marshall, Chris J. D. Hardy, Lucy L. Russell, Camilla N. Clark, Katrina M. Dick, Emilie V. Brotherhood, Rebecca L. Bond, Catherine J. Mummery, Jonathan M. Schott, Jonathan D. Rohrer, James M. Kilner, Jason D. Warren
FRONTIERS IN NEUROLOGY
(2017)
Article
Psychology, Biological
E. R. Palser, A. Fotopoulou, E. Pellicano, J. M. Kilner
BIOLOGICAL PSYCHOLOGY
(2018)
Article
Neurosciences
Antonella Macerollo, Clare Palmer, Thomas Foltynie, Prasad Korlipara, Patricia Limousin, Mark Edwards, James M. Kilner
EUROPEAN JOURNAL OF NEUROSCIENCE
(2018)
Review
Neurosciences
Antonella Macerollo, Matt J. N. Brown, James M. Kilner, Robert Chen
TRENDS IN NEUROSCIENCES
(2018)
Article
Multidisciplinary Sciences
Charles R. Marshall, Chris J. D. Hardy, Lucy L. Russell, Camilla N. Clark, Rebecca L. Bond, Katrina M. Dick, Emilie V. Brotherhood, Cath J. Mummery, Jonathan M. Schott, Jonathan D. Rohrer, James M. Kilner, Jason D. Warren
SCIENTIFIC REPORTS
(2018)
Article
Clinical Neurology
Charles R. Marshall, Christopher J. D. Hardy, Micah Allen, Lucy L. Russell, Camilla N. Clark, Rebecca L. Bond, Katrina M. Dick, Emilie V. Brotherhood, Jonathan D. Rohrer, James M. Kilner, Jason D. Warren
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY
(2018)
Article
Multidisciplinary Sciences
Lucia Ricciardi, Federica Visco-Comandini, Roberto Erro, Francesca Morgante, Matteo Bologna, Alfonso Fasano, Diego Ricciardi, Mark J. Edwards, James Kilner
Article
Multidisciplinary Sciences
Eleanor R. Palser, Clare E. Palmer, Alejandro Galvez-Pol, Ricci Hannah, Aikaterini Fotopoulou, James M. Kilner
Article
Clinical Neurology
Lucia Ricciardi, Federica Visco-Comandini, Roberto Erro, Francesca Morgante, Daniele Volpe, James Kilner, Mark J. Edwards, Matteo Bologna
JOURNAL OF NEURAL TRANSMISSION
(2018)
Article
Multidisciplinary Sciences
Alejandro Galvez-Pol, Marcos Nadal, James Kilner
Summary: The study examined people's emotional representations of space and found that happy memories were consistent with specific spatial locations, but varied depending on individuals' affective state and interoceptive sensibility. The results suggest that emotional representations of the environment are influenced by the naturalness of places, as well as by individuals' affective state and interoceptive sensibility.
SCIENTIFIC REPORTS
(2021)
Article
Biology
Alejandro Galvez-Pol, Pavandeep Virdee, Javier Villacampa, James Kilner
Summary: Perception and cognition are modulated by the phase of the cardiac signal. The duration of touch varies with the cardiac phase, with touches initiated in the systole phase lasting longer than those initiated in the diastole phase. Active sensing is adjusted to the internal bodily cycles.
Article
Psychology, Experimental
E. R. Palser, A. Fotopoulou, J. M. Kilner
CONSCIOUSNESS AND COGNITION
(2018)
Article
Psychology, Developmental
Catherine Manning, James Kilner, Louise Neil, Themelis Karaminis, Elizabeth Pellicano
DEVELOPMENTAL SCIENCE
(2017)
Article
Neurosciences
Sasha Ondobaka, James Kilner, Karl Friston
BRAIN AND COGNITION
(2017)
