Genetic Testing for Early Detection of Individuals at Risk of Coronary Heart Disease and Monitoring Response to Therapy: Challenges and Promises

Aspirin for the Prevention of Cardiovascular Disease: U.S. Preventive Services Task Force Recommendation Statement

(2013)   ANNALS OF INTERNAL MEDICINE

Kinesin-Like Protein 6 (KIF6) Polymorphism and the Efficacy of Rosuvastatin in Primary Prevention

(2011) Paul M Ridker et al.   Circulation-Cardiovascular Genetics

No Impact of KIF6 Genotype on Vascular Risk and Statin Response Among 18,348 Randomized Patients in the Heart Protection Study

(2011) Jemma C. Hopewell et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

(2011) Muredach P Reilly et al.   LANCET

9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response

(2011) Olivier Harismendy et al.   NATURE

Charting a course for genomic medicine from base pairs to bedside

(2011) Eric D. Green et al.   NATURE

Deflating the Genomic Bubble

(2011) J. P. Evans et al.   SCIENCE

From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics

(2011) Bob Wilffert et al.   International Journal of Clinical Pharmacy

Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project

(2011) Guillaume Lettre et al.   PLoS Genetics

KIF6 Polymorphism as a Predictor of Risk of Coronary Events and of Clinical Event Reduction by Statin Therapy

(2010) Yonghong Li et al.   AMERICAN JOURNAL OF CARDIOLOGY

Statins and All-Cause Mortality in High-Risk Primary Prevention

(2010) Kausik K. Ray   ARCHIVES OF INTERNAL MEDICINE

Improved Prediction of Cardiovascular Disease Based on a Panel of Single Nucleotide Polymorphisms Identified Through Genome-Wide Association Studies

(2010) Robert W. Davies et al.   Circulation-Cardiovascular Genetics

Gene Dosage of the Common Variant 9p21 Predicts Severity of Coronary Artery Disease

(2010) Sonny Dandona et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Identification of Genetic Variants Associated With Response to Statin Therapy

(2009) Jessica L. Mega et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Impact of Adding a Single Allele in the 9p21 Locus to Traditional Risk Factors on Reclassification of Coronary Heart Disease Risk and Implications for Lipid-Modifying Therapy in the Atherosclerosis Risk in Communities Study

(2009) Ariel Brautbar et al.   Circulation-Cardiovascular Genetics

Are predictive risk scores useful?

(2009) Valentin Fuster   Nature Reviews Cardiology

APOE gene polymorphisms and response to statin therapy

(2009) E Zintzaras et al.   PHARMACOGENOMICS JOURNAL

Coronary Artery Calcification Compared With Carotid Intima-Media Thickness in the Prediction of Cardiovascular Disease IncidenceThe Multi-Ethnic Study of Atherosclerosis (MESA)

(2008) Aaron R. Folsom   ARCHIVES OF INTERNAL MEDICINE

Polymorphism in the apolipoprotein(a) gene, plasma lipoprotein(a), cardiovascular disease, and low-dose aspirin therapy

(2008) Daniel I. Chasman et al.   ATHEROSCLEROSIS

Lipid Management to Reduce Cardiovascular Risk: A New Strategy Is Required

(2008) H. Robert Superko et al.   CIRCULATION

Genetic Loci Associated With Plasma Concentration of Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein Cholesterol, Triglycerides, Apolipoprotein A1, and Apolipoprotein B Among 6382 White Women in Genome-Wide Analysis With Replication

(2008) Daniel I. Chasman et al.   Circulation-Cardiovascular Genetics

Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study

(2008) Themistocles L. Assimes et al.   HUMAN MOLECULAR GENETICS

Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations

(2008) Kunihiko Hinohara et al.   JOURNAL OF HUMAN GENETICS

An association between angiotensin II type 2 receptor gene A/C3123 polymorphism and glycemic control marker in a general Japanese population

(2008) Kazuhiko Kotani et al.   MOLECULAR BIOLOGY REPORTS

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

(2008) Anna Helgadottir et al.   NATURE GENETICS

Personalized Medicine: A Reality Within this Decade

(2008) Robert Roberts   Journal of Cardiovascular Translational Research