Article
Cell Biology
Mahmuda Akter, Jun Sup Lim, Eun Ha Choi, Ihn Han
Summary: Glioblastoma multiforme (GBM) is a highly malignant and rapidly advancing astrocytic brain tumor in adults, with current treatment options including chemotherapy, surgical resection, and radiation. However, challenges such as drug release, tumor resistance, and limitations of conventional methods call for new therapies. Non-thermal biocompatible plasma has shown promise in selectively targeting cancer cells while sparing normal cells, making it a potential efficient and safe clinical device for brain cancer therapy.
Article
Chemistry, Multidisciplinary
Andrea Jurov, Spela Kos, Natasa Hojnik, Ivana Sremacki, Anton Nikiforov, Christophe Leys, Gregor Sersa, Uros Cvelbar
Summary: The study focused on the behavior of skin cells under a non-thermal plasma jet, revealing that direct plasma treatment could lead to low cell viability and induce apoptosis even with short treatment times. The research also highlighted the importance of upgrading and standardizing existing plasma treatment protocols, monitoring gas and liquid chemistries, and standardizing plasma discharge parameters for future research in the field.
APPLIED SCIENCES-BASEL
(2021)
Article
Nanoscience & Nanotechnology
Nazli Turan, Mortaza Saeidi-Javash, Jiahao Chen, Minxiang Zeng, Yanliang Zhang, David B. Go
Summary: The passage discusses the application of atmospheric pressure nonthermal plasmas in sintering printed films, demonstrating the surface modifications achieved through nonthermal plasmas under ambient conditions. These results offer a new direction for future electronic device manufacturing, showcasing the potential of utilizing nonthermal plasmas for additive manufacturing on flexible and low-melting-point materials.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Physics, Applied
Huifeng Miao, Zhibo Zhang, Yun Wu, Wei Cui, Yinghong Li
Summary: A novel semiconductor enhanced plasma synthetic jet actuator (SEPSJA) with reduced driving voltage and improved jet performance is proposed in this study, showing better efficiency and higher jet velocity compared to traditional PSJA. The SEPSJA is worth further exploration in the field of flow control.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Geosciences, Multidisciplinary
Savvas Raptis, Tomas Karlsson, Andris Vaivads, Martin Lindberg, Andreas Johlander, Henriette Trollvik
Summary: In this study, the properties of a high-speed plasma jet downstream of the Quasi-parallel bow shock were investigated using high-resolution data. It was found that the jet is a kinetic structure with highly variable velocity distributions. The jet consists of a cold/fast component and a hotter/slower background population, and it shows similarities to upstream solar wind beams.
GEOPHYSICAL RESEARCH LETTERS
(2022)
Article
Physics, Multidisciplinary
Shaohui Jin, Lanlan Nie, Rusen Zhou, Jingyi Luo, Xinpei Lu
Summary: This study reports an air plasma jet driven by ionization in the afterglow region, using ambient air as the inducer. The results show that the nozzle diameter plays an essential role in forming the air plasma jet.
FRONTIERS IN PHYSICS
(2022)
Article
Mechanics
Xiuxiu Chen, Zhengzhong Sun
Summary: This article investigates the energy transformation characteristics of the plasma synthetic jet actuator (PSJA) through theoretical, experimental, and numerical research. The results show that the size and formation time of the plasma kernel can be predicted and the peak pressure and temperature rise in the cavity can be calculated. The proportion of kinetic energy increases linearly with non-dimensional deposition energy, while potential energy has a reverse tendency with non-dimensional cavity volume and deposition energy.
Article
Immunology
Akshay J. Patel, Naeem Khan, Alex Richter, Babu Naidu, Mark T. Drayson, Gary W. Middleton
Summary: B cells play a key role in lung cancer pathogenesis and response to immunotherapy. The B cell repertoire differs between tumor and circulation, with a diverse range of plasma cell and memory cell phenotypes in lung cancer. The influence of smoking and tumor type on the B cell repertoire is limited.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Engineering, Multidisciplinary
Keita Shimada, Ryuki Morita, Masayoshi Mizutani, Tsunemoto Kuriyagawa
Summary: Powder jet deposition (PJD) is a spray coating method that can be done under atmospheric pressure and room temperature. By applying an atmospheric-pressure plasma jet (APPJ) assistance, the deposition rate of PJD can be increased.
PRECISION ENGINEERING-JOURNAL OF THE INTERNATIONAL SOCIETIES FOR PRECISION ENGINEERING AND NANOTECHNOLOGY
(2023)
Article
Oncology
Shuxin Zhang, Jun Zhang, Xinlei Hu, Senlin Yin, Yunbo Yuan, Lin Xia, Feng Cao, Xiaoqin Yan, Ziyue Yan, Qing Mao, Dan Xie, Yanhui Liu
Summary: A liquid biopsy method based on sequencing of plasma cfDNA fragments carrying 5hmC has been developed, which can detect brain gliomas and predict the aggressiveness of the tumors.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Engineering, Electrical & Electronic
Huifeng Miao, Zhibo Zhang, Yun Wu, Yangyang He, Yinghong Li
Summary: This study introduces a novel self trigger three-electrode plasma synthetic jet actuator that can extend the electrode distance with low breakdown voltage, leading to higher precursor shock velocity and discharge efficiency compared to traditional PSJA.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Article
Engineering, Chemical
Zhitong Chen, Richard Obenchain, Richard E. Wirz
Summary: Researchers developed a single-electrode tiny plasma jet for clinical biomedical applications, studying the effect of voltage input and flow rate on the jet length and physical parameters. Interactions between the tiny plasma jet and different subjects showed an increase in ROS/RNS intensity as the distance decreased. These findings suggest the potential use of the tiny plasma jet device in clinical biomedical applications.
Article
Physics, Applied
Eric Freund, Lea Miebach, Ramona Clemen, Michael Schmidt, Amanda Heidecke, Thomas von Woedtke, Klaus-Dieter Weltmann, Stephan Kersting, Sander Bekeschus
Summary: Cold physical plasma is a new anticancer agent being developed, with promising applications in chemotherapeutic regimens. However, generating large volumes of plasma-oxidized liquid for practical use remains a challenge. In this study, the use of spark discharge-oxidized saline was found to have a lower tumor burden reduction compared to medical plasma jet kINPen, but showed significant immunomodulatory effects on various peritoneal cytokines.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Materials Science, Coatings & Films
Hongcheng Zhu, Linxiu Jiang, Shouru Xie, Yongrong Jiang, Hua Li
Summary: This study demonstrates that a needle-ring discharge device combined with an ion-wind generator can create a plasma-jet system with self-inlet gas, improving stability and brightness of the plasma jet. Additionally, the inclusion of ion wind enhances sterilization effects and increases the sterilization range.
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A
(2021)
Article
Engineering, Aerospace
Rubing Liu, Shenghui Xue, Wentao Wei, Qi Lin, Kun Tang
Summary: This study proposes an air-supplied actuator with a check valve externally connected to the cavity to improve its gas-supplying ability and jet performance. High-speed schlieren is employed to photograph the internal flow field of the discharge chamber, revealing that the inhalation airflow velocity of the jet orifice is doubled when the actuator is continuously working in the effective frequency band under the combined action of additional air supply from the check valve in the inhalation recovery stage. The results have important implications for the performance optimization of the air-supplied actuator.
Review
Multidisciplinary Sciences
Neha Kaushik, Sarmistha Mitra, Eun Jung Baek, Linh Nhat Nguyen, Pradeep Bhartiya, June Hyun Kim, Eun Ha Choi, Nagendra Kumar Kaushik
Summary: This review critically examines methods for generating reactive oxygen species (ROS) and explores their potential as a solution for virus deactivation. The study highlights the ability of ROS to directly eradicate pathogens through oxidative stress and indirectly through non-oxidative mechanisms. Additionally, the novel and environmentally friendly cold plasma delivery system for virus destruction is discussed in detail.
JOURNAL OF ADVANCED RESEARCH
(2023)
Article
Engineering, Environmental
Choe Earn Choong, So Yeon Yoon, Minhee Kim, Gooyong Lee, Sang-Hyoun Kim, Byong-Hun Jeon, Jaeyoung Choi, Yeomin Yoon, Eun Ha Choi, Min Jang
Summary: Hydrophobic sulfur (S) core-shell-layered nano-zero-valent iron (Fe) (S-nZVI) was prepared for NO3- reduction using a post-sulfidation method with varying Fe/S mass ratios. S(0.125)ZVI (Fe/S = 0.125) showed good N-O cleavage properties due to high electron transfer efficiency and low surface passivation. It exhibited higher selectivity of NO3- reduction toward N-2 than sole nZVI in synthetic and actual NO3- groundwater.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Kien Tiek Wong, So Yeon Yoon, Seok Byum Jang, Nurhaslina Abd Rahman, Choe Earn Choong, Young June Hong, Sang-Eun Oh, Eun Ha Choi, Min Jang
Summary: Atmospheric non-thermal dielectric barrier discharge (DBD) plasma has been widely studied due to its cost-efficiency and environmental friendliness. However, its limitations have hindered its extensive application. In this study, the DBD plasma was used to degrade three pharmaceutically active compounds (PhACs), and the combination of plasma and electrolysis was found to be an effective approach for their removal. The production of NH3 as a by-product also adds value to the system.
Review
Biochemistry & Molecular Biology
Tabrez Faruqui, Mohd Sajid Khan, Yusuf Akhter, Salman Khan, Zeeshan Rafi, Mohd Saeed, Ihn Han, Eun-Ha Choi, Dharmendra Kumar Yadav
Summary: The receptor for advanced glycation end products (RAGE) is a member of the immunoglobulin family that is overexpressed in several cancers. RAGE serves as an important node for the initiation and stimulation of cell stress and growth signaling mechanisms that promote carcinogenesis, tumor propagation, and metastatic potential. Inhibiting the interaction of RAGE with its ligands could provide an effective strategy for cancer treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Shweta B. Borkar, Manorma Negi, Neha Kaushik, Shaik Abdul Munnaf, Linh Nhat Nguyen, Eun Ha Choi, Nagendra Kumar Kaushik
Summary: The proportion of resistant bacteria will increase over time, which is a major concern. Effective and biocompatible therapeutic strategies are urgently needed to combat these bacteria. Non-thermal plasma has been extensively studied for its antibacterial activity. This study investigates the inactivation efficiency and mechanisms of plasma-generated nitric oxide water (PG-NOW) on pathogenic Gram-negative and Gram-positive bacteria in water, air, soil, and food. Results showed that PG-NOW treatment effectively inhibits bacterial growth and accumulates nitric oxide within the cells. Gene expressions related to nitrosative stress and oxidative stress were also analyzed, supporting the nitrosative effect of PG-NOW. Additionally, changes in cell morphology were observed. These findings provide evidence for the further development of PG-NOW-based antibacterial treatments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Afza Ahmad, Rohit Kumar Tiwari, Mohd Saeed, Hadba Al-Amrah, Ihn Han, Eun-Ha Choi, Dharmendra K. K. Yadav, Irfan Ahmad Ansari
Summary: In recent times, there has been a significant increase in focusing on the hedgehog (HH)/GLI signaling pathway as a therapeutic target for cervical cancer. The HH pathway is known to play a critical role in the development of cervical cancer and is also associated with recurrence and chemoresistance. Carvacrol (CAR) has previously been shown to inhibit proliferation in prostate cancer cells by targeting the Notch signaling pathway, making it a rational choice to study its antiproliferative effects in cervical cancer cells. This study aimed to investigate the anticancer and apoptotic potential of CAR in C33A cervical cancer cells and explore the underlying mechanisms.
FRONTIERS IN CHEMISTRY
(2023)
Article
Engineering, Environmental
Shaik Abdul Munnaf, Jun Sup Lim, Janardhan Reddy Koduru, Eun Ha Choi
Summary: In this study, non-thermal plasma discharge was used to potentially remove As(III) in contaminated water, achieving enhanced redox adsorption. Reactive species generated by plasma-water interaction were utilized to transform As(III) to As(V) and modify the surface of the adsorbent, MnOFe2O3. The catalytic adsorption ability of the adsorbent was improved by 30% via the redox adsorptive mechanism. Batch kinetics and isotherm studies demonstrated the effectiveness of the adsorption process, and the adsorption yield was estimated through surface analysis techniques.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Review
Environmental Sciences
Paritosh Patel, Aditya Nandi, Suresh K. Verma, Neha Kaushik, Mrutyunjay Suar, Eun Ha Choi, Nagendra Kumar Kaushik
Summary: Emerging bio-contaminants, such as viruses, have had a significant impact on the health and environment of countries worldwide. Understanding the behavior of viruses is crucial in developing targeted therapeutic and vaccination treatments. Animal models, including non-human primates, rodents, and rabbits, offer advantages in assessing the risks of viral infections and chemical toxins, but their maintenance and experimental redundancy are issues. Therefore, exploring alternative animal models, such as zebrafish, is important. This review focuses on zebrafish traits and their potential in monitoring emerging bio-contaminants, particularly viruses like coronaviridae and poxviridae.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Engineering, Electrical & Electronic
Tirtha Raj Acharya, Dinesh Kumar Chaudhary, Sandhya Gautam, Amrendra Kumar Singh, Rajesh Shrestha, Bishwa Chandra Adhikari, Prajwal Lamichhane, Bhupal Paudyal, Nagendra Kumar Kaushik, Eun Ha Choi
Summary: Thin films of zinc oxide (ZnO) were deposited on glass substrates using chemical bath deposition (CBD) with varied deposition time. The properties and formaldehyde gas responsiveness of the ZnO films were studied in relation to nanoparticle grain sizes. The results showed that longer deposition duration with larger grains led to higher gas response at room temperature. The ZnO films deposited for 1, 2, and 3 h exhibited maximum responses of 5.5, 11.0, and 17.8, respectively, at 400 ppm formaldehyde gas. Additionally, the films could detect as low as 100, 25, and 12 ppm of formaldehyde, respectively.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Review
Biochemistry & Molecular Biology
Apurva Jaiswal, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik
Summary: Despite recent advances in cancer therapy, triple-negative breast cancers (TNBCs) continue to be the most relapsing cancer subtype due to their propensity to develop resistance against available therapies. Non-coding RNAs (ncRNAs) have emerged as critical regulators of cancer hallmarks, and aberrant expression of ncRNAs can modulate oncogenic or tumor suppressive signaling, thereby reducing responsiveness to anti-tumor interventions. This review provides a systematic overview of ncRNA biogenesis and downstream molecular mechanisms, as well as ncRNA-based strategies and challenges for targeting chemo-, radio-, and immunoresistance in TNBCs from a clinical perspective.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
(2023)
Article
Physics, Applied
Prajwal Lamichhane, Tirtha R. Acharya, Jaewoo Park, Kirubel A. Amsalu, Byoungchoo Park, Eun Ha Choi
Summary: This study investigates the effects of nonthermal plasma characteristics on surface treatments of polyvinyl alcohol. Various diagnostics, such as Raman spectroscopy, work of adhesion, optical emission spectroscopy, and current-voltage measurements, were used. The findings highlight the importance of controlling the plasma's electron temperature and density to achieve desired surface treatment outcomes. Plasma jets with varying electron temperatures are found to be more suitable for different surface treatments, with high electron temperatures (>1.1 eV) suitable for functional group insertion and low electron temperatures for plasma etching, which increases surface roughness significantly.
PLASMA PROCESSES AND POLYMERS
(2023)
Article
Chemistry, Physical
Muhammad Ali, Amir Muhammad Afzal, Muhammad Waqas Iqbal, Asad Ur Rehman, Saikh Mohammad Wabaidur, Essam A. Al-Ammar, Sohail Mumtaz, Eun Ha Choi
Summary: In this study, rGO and CoMnS nanostructures were synthesized and their structural and electrochemical properties were measured. The rGO@CoMnS composite electrode material showed a superior specific capacity of 1355.8 C/g compared to the reference electrode (747.6 C/g) in a 3-electrode measurement system. The estimated specific capacitance was 2238 F/g. This study provides new opportunities for designing high-performance energy devices.
Review
Biotechnology & Applied Microbiology
Himani Singh, Niharika, Pradeep Lamichhane, Ravi Gupta, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik
Summary: Pesticides have been widely used in modern agriculture to ensure good harvests, but their excessive use has caused significant environmental degradation and toxicity to non-target organisms. Plants have developed mechanisms, such as the production of secondary metabolites, to reduce the toxicity of pesticides. Recent studies have highlighted the potential role of plasma technology in mitigating environmental stresses.
PLANT BIOTECHNOLOGY REPORTS
(2023)
Article
Engineering, Biomedical
Nagendra Kumar Kaushik, Pradeep Bhartiya, Neha Kaushik, Yungoh Shin, Linh Nhat Nguyen, Jang Sick Park, Doyoung Kim, Eun Ha Choi
Summary: This study demonstrates that nitric oxide enriched plasma-activated water (NO-PAW), generated by a microwave plasma system, effectively inhibits coronavirus infection in host lung cells and improves host antiviral responses.
BIOACTIVE MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Honggyun Kim, Jamal Aziz, Vijay D. Chavan, Deok-kee Kim
Summary: Silicon nitride films were prepared using plasma enhanced chemical vapor deposition with different trap densities induced by adjusting the RF power ratio. It was found that the film's trap density was lowest under compressive stress and increased under tensile stress. This study has significant implications for the formation of durable nitride films in various electronic and optoelectronic applications.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Qiang Yu, Huwei Zhao, Yue Zhao
Summary: Zinc oxide thin films and Al-doped zinc oxide films were prepared and characterized in this study. The addition of Al ions was found to change the growth orientation, increase the grain size, and enhance the absorption intensity in the visible light region. Furthermore, the addition of Al ions also increased the forward current in the heterojunction.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Sang Woo Lee, Min Sun Park, Sangwon Wi, So Yeon Lim, Yeseul Lee, Jin-Seok Chung, Sang Mo Yang
Summary: In this study, we investigated the dynamics of domain switching in pristine and fatigued BiFeO3 capacitors through experimental observations and measurements. The results showed that the switching in the pristine capacitors was dominantly driven by domain growth, while the fatigued capacitors exhibited two different switching dynamics, in which nucleation played a critical role.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Boshi Wang, Tianyi Wang, Yufang Liu, Kun Yu
Summary: In this paper, a tunable and anisotropic perfect absorber composed of anisotropic black phosphorus (BP) and isotropic graphene is proposed. The structure exhibits high absorption and strong anisotropic plasma response. The resonance characteristics can be effectively controlled by adjusting geometric parameters and doping levels, offering potential applications.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Xiaolan Liu, Chunyang Li, Tonghui Yang, Naiqiang Yin, Gangling Zhao
Summary: Water drop triboelectric nanogenerators (WD-TENGs) can harvest energy from raindrops and improve the output performance of TENGs.
CURRENT APPLIED PHYSICS
(2024)
