Article
Chemistry, Analytical
Ning Xia, Gang Liu, Xinyao Yi
Summary: This study presented a heterogeneous surface plasmon resonance (SPR) method for protease detection by integrating homogeneous reaction, with enhanced sensitivity through signal amplification of streptavidin (SA)-conjugated immunoglobulin G (SA-IgG).
Article
Chemistry, Analytical
Yong Chang, Xiaohua Ma, Ting Sun, Lin Liu, Yuanqiang Hao
Summary: A novel heterogeneous electrochemical method for kinase detection was proposed in this work, which does not require immobilization of the probe during phosphorylation. The method captures the biotinylated phosphopeptide on a neutravidin-modified electrode and recognizes phosphate groups using conjugates of biotinylated Phos-tag and ferrocene-capped gold nanoparticles. This strategy is simple, sensitive, and specific, integrating the advantages of homogeneous reaction and heterogeneous detection.
Article
Chemistry, Physical
Yahui Guo, Mofan Wang, Wenya Zhang, Hang Yu, Yuliang Cheng, Yunfei Xie, Hongliu Ding, Weirong Yao, He Qian
Summary: A fluorescence biosensor for Norovirus RNA was developed using catalytic hairpin assembly (CHA) and magnetic separation techniques, with the aim of highly sensitive detection at room temperature. The sensor showed a good linear response towards target RNA concentrations in the range of 1.0-100 nM with a detection limit of 0.82 nM. A quenching phenomenon observed in the sensor system was attributed to the interaction between the biotin-avidin complex and magnetic nanoparticles.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Maria Laura Alfieri, Marina Massaro, Marco D'Ischia, Gerardino D'Errico, Noemi Gallucci, Michelangelo Gruttadauria, Mariano Licciardi, Leonarda F. Liotta, Giuseppe Nicotra, Gianfranco Sfuncia, Serena Riela
Summary: This study achieved the site-selective functionalization of HNTs with polydopamine by exploiting the basicity of ZnO nanoparticles anchored on the HNTs external surface. The introduction of PDA coating affected the aqueous stability of the nanotubes and induced a local thermal rise under near-infrared irradiation.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Marco Raabe, Astrid Johanna Heck, Siska Fuehrer, Dominik Schauenburg, Michaela Pieszka, Tao Wang, Maksymilian Marek Zegota, Lutz Nuhn, David Y. W. Ng, Seah Ling Kuan, Tanja Weil
Summary: By combining a supramolecular protein-based assembly platform and a pH-responsive linker, the authors have devised a convenient assembly of a trivalent protein-drug conjugate that possesses distinct features of ADCs. These ADC-like conjugates target cancer cells that overexpress somatostatin receptors, enable controlled release in the cancer cell microenvironment through a new pH-responsive biotin linker, and exhibit stability in biological media.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Engineering, Environmental
Yu Wang, Xudong Zhao, Man Zhang, Xuan Sun, Jialei Bai, Yuan Peng, Shuang Li, Dianpeng Han, Shuyue Ren, Jiang Wang, Tie Han, Yifei Gao, Baoan Ning, Zhixian Gao
Summary: An avidin biotin complex immunosorbent assay based on upconversion nanoparticles was developed for accurate detection of antibiotics in a shorter period of time. The method utilizes double signal amplification for improved sensitivity and uses a 96-well enzyme-linked plate for high-throughput detection.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Lin Liu, Yong Chang, Xingyue Ji, Jiayu Chen, Mengyu Zhang, Suling Yang
Summary: A sensitive electrochemical biosensor for telomerase detection was developed by integrating homogeneous extension and hybridization reactions and surface-tethered detection. The biosensor exhibited strong electrochemical signals from the oxidation of Fc tags when the bio-DNA/DNA/Fc-AuNP hybrids were tethered to streptavidin-modified electrodes through specific avidin-biotin interactions. This method has great potential in clinical diagnosis and anti-cancer drug development.
Article
Materials Science, Multidisciplinary
Dongsik Nam, Jiyeon Kim, Eunhye Hwang, Joohan Nam, Hyein Jeong, Tae-Hyuk Kwon, Wonyoung Choe
Summary: The chemical environment of pores is crucial for various applications of porous solids, and metal-organic polyhedra (MOPs) based on Zr have been shown to be a versatile platform with controllable intrinsic pores. By utilizing mixed-cage and mixed-linker synthesis approaches, different levels of complexity in functionality assembly can be achieved. This study demonstrates the potential of MOPs as a unique multivariate platform for studying the emerging properties of multivariate porous solids.
Article
Physics, Applied
Kai Hashino, Daiya Mombayashi, Yuto Nakatani, Azusa Oshima, Masumi Yamaguchi, Akira Heya, Koji Sumitomo
Summary: Lipid bilayers suspended over microwells on Si substrates are promising platforms for nanobiodevices that mimic cell membranes. By using the biotin-avidin interaction, vesicles can be selectively arranged on the freestanding region of the lipid bilayer, facilitating the introduction of biomolecules into the nanobiodevices.
JAPANESE JOURNAL OF APPLIED PHYSICS
(2022)
Review
Biochemistry & Molecular Biology
Jessica A. Buchanan, Nikhil R. Varghese, Caitlin L. Johnston, Margaret Sunde
Summary: Functional amyloids are fibrillar protein structures that generate novel and advantageous biological functions through their assembly, and their structures can accommodate various amino acid sequences and impose selectivity on the assembly process. In functional amyloids, the polymeric β-sheet rich structure provides unique control mechanisms and finely tuned structures for assembly or disassembly in response to physiological or environmental cues. Understanding the molecular basis for controlling the structure and functionality of natural amyloids can guide the development of therapies for amyloid-associated diseases and the design of innovative biomaterials.
JOURNAL OF MOLECULAR BIOLOGY
(2023)
Article
Crystallography
Dong Chen, Zhongren Nan
Summary: Three-dimensional manganese oxide particles were prepared via layer-by-layer assembly and showed efficient adsorption of Zn2+, Pb2+, and Cu2+ from slightly alkaline water.
Article
Chemistry, Applied
Gongshuai Song, Jiayuan Liu, Qi Wang, Danli Wang, Bingquan Chu, Ling Li, Gongnian Xiao, Jinyan Gong, Fuping Zheng
Summary: The study demonstrated that hollow dextran sulfate/chitosan-coated zein nanoparticles loaded with crocin can serve as a promising delivery system for effective treatment of Alzheimer's disease, showing better controlled release behavior and antioxidant activity.
FOOD HYDROCOLLOIDS
(2022)
Article
Cardiac & Cardiovascular Systems
Feng Gao, Haoyu Sun, Xiang Li, Pingnian He
Summary: This study developed a new approach that enables the measurement of permeability coefficient in microvessels developed in nonpermeable microfluidic platforms using avidin-biotin technology. The model possesses in vivo-like endothelial junctions, glycocalyx, and permeability properties, advancing microfluidics in microvascular research, suitable for a wide range of biomedical and clinical applications.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2022)
Article
Engineering, Biomedical
Pavol Stefik, Adriana Annusova, Boris Lakatos, Katarina Elefantova, Lucia Cepcova, Monika Hofbauerova, Anna Kalosi, Matej Jergel, Eva Majkova, Peter Siffalovic
Summary: AML is an aggressive cancer type with systemic chemotherapy as the primary treatment, but targeted drug therapies are becoming more popular due to their ability to bypass normal tissues. MoS2 nanomaterials functionalized with tumor-recognizing elements show promise in improving treatment specificity and reducing side effects. The study demonstrated efficient targeting of AML cells using MoS2 nanoflakes functionalized with anti-CD33 antibody, suggesting the potential utilization of MoS2-based nanomaterials in AML diagnosis and therapy.
BIOMEDICAL MATERIALS
(2021)
Article
Polymer Science
Saman Abrishamkar, Abbas Mohammadi, Jimena De La Vega, De-Yi Wang, Ehsan Naderi Kalali
Summary: This study investigated the effect of LbL coatings based on LDH-GO and LDH-GOSC4A on the fire properties and dye adsorption behavior of flexible polyurethane foam. The results showed that LDH-GOSC4A coatings exhibited better flame retardancy compared to LDH-GO coatings. The PUF/LDH-GOSC4A 9BL foam showed the best fire properties and had a significantly reduced adsorption capacity for MB.
POLYMER DEGRADATION AND STABILITY
(2023)
Article
Chemistry, Physical
Hyeonggeun Choi, Min-Cheol Kim, Yeonsu Park, Suok Lee, Wook Ahn, John Hong, Jung Inn Sohn, A-Rang Jang, Young-Woo Lee
Summary: This study presents a novel wearable fiber-based flexible energy storage system using hydroquinone as a catalytically active redox mediator, demonstrating its superior performance in improving energy storage capacity and long-term stability.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Polymer Science
Yong-il Ko, Min-Jae Kim, Dong-Yun Lee, Jungtae Nam, A-Rang Jang, Jeong-O Lee, Keun-Soo Kim
Summary: In this study, highly sensitive carbon nanomaterials were synthesized using a local laser scribing method, providing a simple and cost-effective approach to create these materials.
Article
Chemistry, Multidisciplinary
Sangyeon Pak, Seunghun Jang, Taehun Kim, Jungmoon Lim, Jae Seok Hwang, Yuljae Cho, Hyunju Chang, A-Rang Jang, Kyung-Ho Park, John Hong, SeungNam Cha
Summary: The study presents an innovative device configuration with metallic CuS electrodes to induce self-healing of sulfur vacancy defects in the MoS2 channel, leading to significantly improved device performance. The self-healed MoS2 transistors with CuS electrodes exhibit outstanding room temperature mobility and photoresponsivity, demonstrating a promising strategy for high performance TMDCs-based devices.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Physical
Yong-il Ko, Geonhee Lee, Min Jae Kim, Dong Yun Lee, Jungtae Nam, A-Rang Jang, Jeong-O Lee, Keun Soo Kim
Summary: This study synthesized carbon nanomaterials using local laser-scribing on a substrate coated with a Cu-embedded polyimide (PI) thin film to reduce processing time and cost. The laser absorption of the Cu-embedded PI thin film was improved, leading to a three-dimensional structure of the carbon nanomaterial that facilitates gas molecule absorption. When exposed to NO2 and NH3, the electrical resistance of the synthesized carbon nanomaterial changed by -0.79% and +0.33%, respectively.
Article
Chemistry, Physical
A-Rang Jang, Ji Eun Lim, Seunghun Jang, Myung Hyun Kang, Geonhee Lee, Hyunju Chang, EunKyoung Kim, Joung Kyu Park, Jeong-O Lee
Summary: Decorating graphene with synthesized Ag2S nanoparticles significantly enhances gas selectivity and response levels of a chemical sensor. The presence of Ag2S nanoparticles on graphene leads to a dramatic increase in response to acetone vapor, while no noticeable gas response changes were observed for other volatile organic compounds. Density functional theory calculations suggest that the enhanced acetone response is due to higher binding energies and electron transfer between Ag2S and acetone compared to other VOCs.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Physical
Puran Pandey, Kihoon Shin, A-Rang Jang, Min-Kyu Seo, Woong-Ki Hong, Jung Inn Sohn
Summary: This study demonstrates highly sensitive multiplex-detection of organic dyes using SERS substrates with self-assembly arrays of porous AuAg alloy (p-AuAg) NPs, showing excellent enhancement, reproducibility, and detection limits. The high-density built-in and inter nanogaps in the self-assembly arrays of p-AuAg NPs contribute to the significant enhancement of electromagnetic field, supporting potential pathways for practical SERS applications.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Physics, Applied
Min Kyun Sohn, Hardeep Singh, Eun-Mi Kim, Gi Seok Heo, Seoung Woo Choi, Do Gi Phyun, Dae Joon Kang
Summary: This study reports the stability and reversibility of insulator-to-metal transition (IMT) in a vanadium dioxide (VO2) thin film grown on flexible glass substrates under the external strain, and discusses the effects of externally applied tensile strain on the electrical resistance.
APPLIED PHYSICS LETTERS
(2022)
Article
Chemistry, Physical
Suok Lee, Min-Cheol Kim, A-Rang Jang, Jung Inn Sohn, Jong Bea Park, Young-Woo Lee
Summary: This study synthesized novel spindle-shaped ferric oxyhydroxide nanoparticles with a unique hierarchical nanostructure and successfully applied them in electrode preparation, demonstrating high specific capacitance, outstanding cycling stability, and significant electrocatalytic activity for the oxygen evolution reaction.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Ki Hoon Shin, Min-Kyu Seo, Sangyeon Pak, A-Rang Jang, Jung Inn Sohn
Summary: This study presents a detailed analysis of low-frequency Raman modes in bilayers of MoS2, WS2, and WS2/MoS2 heterostructures, grown directly using chemical vapor deposition. The results show the influence of interlayer coupling on vdW heterostructures and the presence of LF Raman modes dependent on twisting angles and interface quality.
Article
Chemistry, Multidisciplinary
Du Won Jeong, Kyuhyoung Kim, Geonhee Lee, Minsoung Kang, Hyunju Chang, A-Rang Jang, Jeong-O Lee
Summary: In this study, we demonstrated that the direct intercalation of alkali-metal cations is not necessary for the redox reaction of Prussian blue. Passivation of Prussian blue thin films with monolayer graphene preserved its electrochemical activity and enhanced its stability. We also showed the potential of a transparent graphene electrode as an efficient hydrogen peroxide transducer.
Article
Physics, Multidisciplinary
Yong-il Ko, Min Jae Kim, Dong Yun Lee, Jungtae Nam, Keun Soo Kim, A-Rang Jang
Summary: This study utilized a laser-assisted chemical vapor deposition system to fabricate laser-scribed carbon nanomaterials for flexible gas sensor applications, reducing cost and process time while maintaining material flexibility.
JOURNAL OF THE KOREAN PHYSICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
A-Rang Jang
Summary: This study investigates the effect of electrodes on the electrical properties of single-layer MoS2 field-effect transistors (FETs). The contact barrier at the MoS2-graphene interface can be modulated, resulting in enhanced performance compared to FETs with Au/Ti electrodes.
Article
Chemistry, Multidisciplinary
Gyu Hyun Jeong, Hye Soung Jang, Jong Chan Yoon, Zonghoon Lee, Jieun Yang, A-Rang Jang, Gyeong Hee Ryu
Summary: A surfactant-assisted method was used to synthesize Zn(OH)2 nanosheets, and the thickness and shape of the synthesized nanosheets were controlled by varying the surfactant concentration. The characteristics of oxygen evolution reaction using ZnO/Zn(OH)2 nanosheets as catalysts were also studied.
Article
Nanoscience & Nanotechnology
Zhiyi Lyu, Yongteng Qian, Dae Joon Kang
Summary: This study presents a transfer method that allows for the efficient transfer of two-dimensional transition metal dichalcogenides (TMDs) with high yield. The method utilizes a water-soluble sodium salt as a sacrificial layer for easy transfer and a catalytic layer for growing high-quality TMDs using chemical vapor deposition. The transferred TMDs maintain their pristine structural and electrical properties, as demonstrated by the fabrication of functional field-effect transistors with excellent performance. This transfer method has wide applicability and enables the easy fabrication of TMD-based electronics and optoelectronics.
Article
Chemistry, Multidisciplinary
Hyunje Park, Jaeseok Hwang, Jaejong Lee, Dae Joon Kang
Summary: This study introduces an EHIP process using an ultrahigh electric field to accelerate pattern growth evolution, overcoming challenges in process parameter controllability and replicate densely packed nanostructures.
Article
Materials Science, Multidisciplinary
Honggyun Kim, Jamal Aziz, Vijay D. Chavan, Deok-kee Kim
Summary: Silicon nitride films were prepared using plasma enhanced chemical vapor deposition with different trap densities induced by adjusting the RF power ratio. It was found that the film's trap density was lowest under compressive stress and increased under tensile stress. This study has significant implications for the formation of durable nitride films in various electronic and optoelectronic applications.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Qiang Yu, Huwei Zhao, Yue Zhao
Summary: Zinc oxide thin films and Al-doped zinc oxide films were prepared and characterized in this study. The addition of Al ions was found to change the growth orientation, increase the grain size, and enhance the absorption intensity in the visible light region. Furthermore, the addition of Al ions also increased the forward current in the heterojunction.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Sang Woo Lee, Min Sun Park, Sangwon Wi, So Yeon Lim, Yeseul Lee, Jin-Seok Chung, Sang Mo Yang
Summary: In this study, we investigated the dynamics of domain switching in pristine and fatigued BiFeO3 capacitors through experimental observations and measurements. The results showed that the switching in the pristine capacitors was dominantly driven by domain growth, while the fatigued capacitors exhibited two different switching dynamics, in which nucleation played a critical role.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Boshi Wang, Tianyi Wang, Yufang Liu, Kun Yu
Summary: In this paper, a tunable and anisotropic perfect absorber composed of anisotropic black phosphorus (BP) and isotropic graphene is proposed. The structure exhibits high absorption and strong anisotropic plasma response. The resonance characteristics can be effectively controlled by adjusting geometric parameters and doping levels, offering potential applications.
CURRENT APPLIED PHYSICS
(2024)
Article
Materials Science, Multidisciplinary
Xiaolan Liu, Chunyang Li, Tonghui Yang, Naiqiang Yin, Gangling Zhao
Summary: Water drop triboelectric nanogenerators (WD-TENGs) can harvest energy from raindrops and improve the output performance of TENGs.
CURRENT APPLIED PHYSICS
(2024)
