N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis

Neuroprotective agents target molecular mechanisms of disease in ALS

(2015) Yongjin Zhu et al.   DRUG DISCOVERY TODAY

N-acetyl- l -tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model

(2015) Wei Li et al.   NEUROBIOLOGY OF DISEASE

The NK1 receptor antagonist N-acetyl-l-tryptophan reduces dyskinesia in a hemi-parkinsonian rodent model

(2014) Emma Thornton et al.   PARKINSONISM & RELATED DISORDERS

Substance P as a Mediator of Neurogenic Inflammation after Balloon Compression Induced Spinal Cord Injury

(2013) Anna V. Leonard et al.   JOURNAL OF NEUROTRAUMA

Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis

(2013) Yi Zhang et al.   NEUROBIOLOGY OF DISEASE

Motoneurons Secrete Angiogenin to Induce RNA Cleavage in Astroglia

(2012) A. Skorupa et al.   JOURNAL OF NEUROSCIENCE

Treatment with a Substance P Receptor Antagonist Is Neuroprotective in the Intrastriatal 6-Hydroxydopamine Model of Early Parkinson's Disease

(2012) Emma Thornton et al.   PLoS One

Valproic acid improves locomotion in vivo after SCI and axonal growth of neurons in vitro

(2011) Lei Lv et al.   EXPERIMENTAL NEUROLOGY

The Melatonin MT1 Receptor Axis Modulates Mutant Huntingtin-Mediated Toxicity

(2011) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Substance P receptor activation induces downregulation of the AMPA receptor functionality in cortical neurons from a genetic model of Amyotrophic Lateral Sclerosis

(2011) Silvia Caioli et al.   NEUROBIOLOGY OF DISEASE

Dipyrone Inhibits Neuronal Cell Death and Diminishes Hypoxic/Ischemic Brain Injury

(2011) Yi Zhang et al.   NEUROSURGERY

HCl-induced inflammatory mediators in esophageal mucosa increase migration and production of H2O2 by peripheral blood leukocytes

(2010) Jie Ma et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Substance P Antagonist Reduces Axonal Injury and Improves Neurologic Outcome When Administered Up to 12 Hours after Traumatic Brain Injury

(2010) James J. Donkin et al.   JOURNAL OF NEUROTRAUMA

A substance P mediated pathway contributes to 6-hydroxydopamine induced cell death

(2010) Emma Thornton et al.   NEUROSCIENCE LETTERS

Substance P antagonists as a therapeutic approach to improving outcome following traumatic brain injury

(2010) Robert Vink et al.   Neurotherapeutics

The Antiapoptotic Activity of Melatonin in Neurodegenerative Diseases

(2009) Xin Wang   CNS Neuroscience & Therapeutics

Substance P is Associated with the Development of Brain Edema and Functional Deficits after Traumatic Brain Injury

(2009) James J Donkin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

SP protects cerebellar granule cells against β-amyloid-induced apoptosis by down-regulation and reduced activity of Kv4 potassium channels

(2009) M. Pieri et al.   NEUROPHARMACOLOGY

Methazolamide and Melatonin Inhibit Mitochondrial Cytochrome C Release and Are Neuroprotective in Experimental Models of Ischemic Injury

(2009) Xin Wang et al.   STROKE

Neuroprotection Against Hypoxic-Ischemic Brain Injury by Inhibiting the Apoptotic Protease Activating Factor-1 Pathway

(2009) Yanqin Gao et al.   STROKE

Substance P accelerates intestinal tissue regeneration after γ-irradiation-induced damage

(2009) Mi-Hyun Kang et al.   WOUND REPAIR AND REGENERATION

Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice

(2008) Steven J. Del Signore et al.   Amyotrophic Lateral Sclerosis

Proteasomes remain intact, but show early focal alteration in their composition in a mouse model of amyotrophic lateral sclerosis

(2008) Edor Kabashi et al.   JOURNAL OF NEUROCHEMISTRY

Inhibitors of Cytochrome c Release with Therapeutic Potential for Huntington's Disease

(2008) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Neurokinin B/NK3 receptors exert feedback inhibition on l-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease

(2008) Xiaoqun Zhang et al.   NEUROPHARMACOLOGY