Dextran sulfate sodium inhibits amyloid-β oligomer binding to cellular prion protein

Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5)

(2014) Laura T. Haas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An N-terminal Fragment of the Prion Protein Binds to Amyloid-β Oligomers and Inhibits Their Neurotoxicityin Vivo

(2013) Brian R. Fluharty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

(2013) Jo V. Rushworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-  Oligomer Toxicity

(2013) V. G. Ostapchenko et al.   JOURNAL OF NEUROSCIENCE

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Postsynaptic Receptors for Amyloid-β Oligomers as Mediators of Neuronal Damage in Alzheimer’s Disease

(2012) Margarita C. Dinamarca et al.   Frontiers in Physiology

Alzheimer's Disease: The Challenge of the Second Century

(2011) D. M. Holtzman et al.   Science Translational Medicine

Prion protein at the crossroads of physiology and disease

(2011) Emiliano Biasini et al.   TRENDS IN NEUROSCIENCES

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an alzheimer's disease model mouse

(2010) Erika Chung et al.   BMC NEUROSCIENCE

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's disease: clinical trials and drug development

(2010) Francesca Mangialasche et al.   LANCET NEUROLOGY

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

Amyloid-β–induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

(2010) Jorge J Palop et al.   NATURE NEUROSCIENCE

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE