Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone

Parkinson's Disease Iron Deposition Caused by Nitric Oxide-Induced Loss of  -Amyloid Precursor Protein

(2015) S. Ayton et al.   JOURNAL OF NEUROSCIENCE

Deferiprone in Friedreich ataxia: A 6-Month randomized controlled trial

(2014) Massimo Pandolfo et al.   ANNALS OF NEUROLOGY

Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease

(2014) Scott Ayton et al.   Molecular Neurodegeneration

Efficacy and safety of deferiprone for the treatment of pantothenate kinase-associated neurodegeneration (PKAN) and neurodegeneration with brain iron accumulation (NBIA): Results from a four years follow-up

(2014) Giovanni Cossu et al.   PARKINSONISM & RELATED DISORDERS

The Multicopper Ferroxidase Hephaestin Enhances Intestinal Iron Absorption in Mice

(2014) Brie K. Fuqua et al.   PLoS One

Targeting Chelatable Iron as a Therapeutic Modality in Parkinson's Disease

(2013) David Devos et al.   ANTIOXIDANTS & REDOX SIGNALING

Effectiveness of Oral Iron Chelator Treatment with Deferasirox in an Aceruloplasminemia Patient with a Novel Ceruloplasmin Gene Mutation

(2013) Yasuhiro Suzuki et al.   INTERNAL MEDICINE

Role and Mechanism of Microglial Activation in Iron-Induced Selective and Progressive Dopaminergic Neurodegeneration

(2013) Wei Zhang et al.   MOLECULAR NEUROBIOLOGY

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Ferroxidase Hephaestin's Cell-Autonomous Role in the Retinal Pigment Epithelium

(2012) Natalie Wolkow et al.   AMERICAN JOURNAL OF PATHOLOGY

Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease

(2012) Scott Ayton et al.   ANNALS OF NEUROLOGY

Aceruloplasminemia

(2011) Natalie Wolkow   ARCHIVES OF OPHTHALMOLOGY

Iron Efflux from Oligodendrocytes Is Differentially Regulated in Gray and White Matter

(2011) K. Schulz et al.   JOURNAL OF NEUROSCIENCE

Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin

(2010) Satoshi Kono et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Rescuing iron-overloaded macrophages by conservative relocation of the accumulated metal

(2010) Yang-Sung Sohn et al.   BRITISH JOURNAL OF PHARMACOLOGY

Identification of Zyklopen, a New Member of the Vertebrate Multicopper Ferroxidase Family, and Characterization in Rodents and Human Cells

(2010) Huijun Chen et al.   JOURNAL OF NUTRITION

Metals, oxidative stress and neurodegenerative disorders

(2010) Klaudia Jomova et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Alpha-synuclein, lipids and Parkinson’s disease

(2010) Violeta Ruipérez et al.   PROGRESS IN LIPID RESEARCH

Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice

(2009) Tohru Kitada et al.   JOURNAL OF NEUROCHEMISTRY

Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapy

(2008) Lakshmi D. Devanur et al.   BIOCHEMICAL JOURNAL

Iron-enhanced paraquat-mediated dopaminergic cell death due to increased oxidative stress as a consequence of microglial activation

(2008) Jun Peng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease

(2008) J. Salazar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA