期刊
JOURNAL OF NATURAL MEDICINES
卷 69, 期 3, 页码 416-420出版社
SPRINGER JAPAN KK
DOI: 10.1007/s11418-015-0891-y
关键词
Marine natural product; Indole alkaloid; Marine sponge; Ircinia sp.
资金
- Foundation for Japanese Chemical Research
- Grants-in-Aid for Scientific Research [25870660] Funding Source: KAKEN
Two new indole derivatives, 5-hydroxy-1H-indole-3-carboxylic acid ethyl ester (1) and 5-hydroxy-1H-indole-3-glyoxylate ethyl ester (2), and seven known indole alkaloids, dragmacidonamine B (3), gesashidine A (4), hyrtiosulawesine (5), hyrtiomanzamine (6), hyrtimomine D (7), hyrtiosine A (8), and 5-hydroxy-1H-indole-3-carbaldehyde (9), were isolated from a marine sponge Ircinia sp., Irciniidae, collected at Iriomote Island. The structures of 1 and 2 were elucidated on the basis of their spectroscopic data. Compound 1 has previously been reported as a synthetic intermediate and this is the first time that it has been obtained from a natural source.
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